A polythioether prepolymer including functional groups capable of being obtained by the reaction: of at least one compound T having a number f of thiol functional group number selected from 2, 3, 4 and 6, with at least one compound E having a number g of epoxy functional groups number selected from 2 and 3. Also, a method of preparation for this prepolymer, a composition including this prepolymer and an oligomer as well as its use as a mastic and a polythioether polymer obtained from this polythioether prepolymer with an oligomer.

A surface coating material includes a plurality of fluorine-containing silicon compounds and an additive. The fluorine-containing silicon compounds include a fluorine-containing (poly)ether moiety, a hydrolytic silane moiety, and a linking group between the fluorine-containing (poly)ether moiety and the hydrolytic silane moiety. The linking group is configured to form a non-covalence interaction between adjacent molecules.

The use of compatible, semi-miscible or miscible polymer compositions as support structures for the 3D printing of objects, including those made from polyether-block-amide copolymers such as PEBAX® block copolymers from Arkema, polyamides such as RILSAN® polyamides from Arkema, polyether ketone ketone such as KEPSTAN® PEKK from Arkema, and fluoropolymers, such a KYNAR® PVDF from Arkema, especially objects of polyvinylidene fluoride and its copolymers. One particularly useful miscible polymer is an acrylic polymer, which is miscible with the fluoropolymer in the melt. The support structure composition provides the needed adhesion to the build plate and to the printed object and support strength during the 3D printing process, yet it is removable after the fluoropolymer object has cooled. The support polymer composition is selected to be stiff and low warping, yet flexible enough to be formed into filaments.

The use of compatible, semi-miscible or miscible polymer compositions as support structures for the 3D printing of objects, including those made from polyether-block-amide copolymers such as PEBAX® block copolymers from Arkema, polyamides such as RILSAN® polyamides from Arkema, polyether ketone ketone such as KEPSTAN® PEKK from Arkema, and fluoropolymers, such a KYNAR® PVDF from Arkema, especially objects of polyvinylidene fluoride and its copolymers. One particularly useful miscible polymer is an acrylic polymer, which is miscible with the fluoropolymer in the melt. The support structure composition provides the needed adhesion to the build plate and to the printed object and support strength during the 3D printing process, yet it is removable after the fluoropolymer object has cooled. The support polymer composition is selected to be stiff and low warping, yet flexible enough to be formed into filaments.

Provided herein are poly-1-hydroxymethylethylene hydroxymethyl formal (PHF)-based drug delivery systems. Also disclosed are methods of making antibody-drug conjugates and methods of treatment using these conjugates.

Provided herein are poly-1-hydroxymethylethylene hydroxymethyl formal (PHF)-based drug delivery systems. Also disclosed are methods of making antibody-drug conjugates and methods of treatment using these conjugates.

The present invention relates to novel (per)fluoropolyether (PFPE) polymers, to a process for their manufacture and to their use as additives in coating compositions.

According to one aspect of the present invention, an organic fluorine compound is represented by a general formula
(R-π-E-CH.sub.2-A-CH.sub.2-E′).sub.n-π′-G  (1B) (where n is an integer of 2 to 5, A is a divalent perfluoropolyether group, π is an arylene group or a single bond, R is an alkenyl group or an alkynyl group, and E and E′ are each independently an ether bond or an ester bond or a group that is represented by a chemical formula
—O—CH.sub.2CH(OH)CH.sub.2O—
π′ is a group in which n+1 hydrogen atoms are separated from benzene, G is an organic group containing a fullerene skeleton, the n number of groups each of which is represented by a general formula
R-π-E-CH.sub.2-A-CH.sub.2-E′-
may be the same or different, and at least one π among the n number of π is an arylene group).

A fluorinated ether compound represented by A-O—(R.sup.f1O).sub.m—R.sup.f2—[C(O)N(R.sup.1)].sub.p-Q.sup.1-C(R.sup.2)[-Q.sup.2-SiR.sup.3.sub.nL.sub.3-n].sub.2, wherein A is a C.sub.1-20 perfluoroalkyl group, R.sup.f1 is a linear fluoroalkylene group, m is an integer of from 2 to 500, R.sup.f2 is a linear fluoroalkylene group, R.sup.1 is a hydrogen atom or an alkyl group, p is 0 or 1, Q.sup.1 is a single bond or an alkylene group, R.sup.2 is a hydrogen atom, a monovalent hydrocarbon group or the like, Q.sup.2 is an alkylene group, R.sup.3 is a hydrogen atom or a monovalent hydrocarbon group, L is a hydrolyzable group, and n is an integer of from 0 to 2 is provided. A fluorinated ether composition and a coating liquid capable of forming a surface layer excellent in initial water/oil repellency, fingerprint stain removability, abrasion resistance, light resistance and chemical resistance, an article having a surface layer, and a method for producing it are also provided.

An electropositive metal electrode coated by an ion-selective conformable polymer provides the negative electrode and the solid-state electrolyte for a rechargeable bi-electrolyte displacement battery that further includes a molten salt electrolyte having a melting temperature below 140° C. interposed between the conformable polymer coating and a positive electrode. Suitable electropositive metals include lithium, sodium, magnesium, and aluminum and the molten salt incorporates a soluble salt of the metal of the negative electrode. Positive electrodes may incorporate metals including Fe, Ni, Bi, Pb, Zn, Sn, and Cu, and thanks to the ion-selective conformable solid-state electrolyte the molten salt is able to incorporate a soluble salt of the metal of the positive electrode. The conformable polymer-coated electropositive metal electrode may be manufactured by a process involving electroplating electropositive metal through a conformable polymer-coated conductive substrate. The conformable polymer-coated conductive substrate may be prepared by coating the conductive substrate in a conformable polymer solution followed by evaporating the solvent. Alternatively, an electropositive metal electrode may be coated directly with the conformable polymer.