The present disclosure relates to a responsive polymer film, a method of preparing the responsive polymer film, and a sensor using the polymer film.

The present disclosure relates to a responsive polymer film, a method of preparing the responsive polymer film, and a sensor using the polymer film.

In various embodiments, the present invention is directed to ABA triblock copolymers having crosslinkable poly(propylene fumarate A blocks and a more flexible poly(lactone) B block formed by sequential ring-opening polymerization and ring-opening copolymerization. These ABA triblock polymers made using ring-opening polymerization of one or more lactone monomers using a bifunctional initiator to form a poly(lactone) B block having terminal hydroxyl groups and the ring-opening copolymerization of maleic anhydride and propylene oxide followed by isomerization of the maleate double bond using an organic base to form the poly(propylene fumarate)(PPF) A blocks. When crosslinked photochemically using, for example, a continuous liquid interface production digital light processing (DLP) Carbon M2 printer, these ABA type triblock copolymers form durable elastomers with tunable degradation and elastic properties. In various embodiments, these polymers are shown to undergo slow, hydrolytic degradation in vitro with minimal loss of mechanical performance during degradation.

In various embodiments, the present invention is directed to ABA triblock copolymers having crosslinkable poly(propylene fumarate A blocks and a more flexible poly(lactone) B block formed by sequential ring-opening polymerization and ring-opening copolymerization. These ABA triblock polymers made using ring-opening polymerization of one or more lactone monomers using a bifunctional initiator to form a poly(lactone) B block having terminal hydroxyl groups and the ring-opening copolymerization of maleic anhydride and propylene oxide followed by isomerization of the maleate double bond using an organic base to form the poly(propylene fumarate)(PPF) A blocks. When crosslinked photochemically using, for example, a continuous liquid interface production digital light processing (DLP) Carbon M2 printer, these ABA type triblock copolymers form durable elastomers with tunable degradation and elastic properties. In various embodiments, these polymers are shown to undergo slow, hydrolytic degradation in vitro with minimal loss of mechanical performance during degradation.

An antistatic agent for thermoplastic resins (Z) containing a block polymer (A) having a block of a hydrophobic polymer (a) and a block of a hydrophilic polymer (b) as structure units, and a C6-C18 branched alkylbenzenesulfonate (S); an antistatic resin composition (Y) containing the antistatic agent (Z) and a thermoplastic resin (E); and a molded article of the antistatic resin composition (Y).

Provided is an antistatic agent (Z) containing: a block polymer (A) having a block of a hydrophobic polymer (a) and a block of a hydrophilic polymer (b) as structure units; and a sulfonate (S), the sulfonate (S) being a salt of an alkylbenzenesulfonic acid anion which has a C6-C18 alkyl group, the sulfonate (S) including at least two alkylbenzenesulfonates different in the number of carbon atoms of the alkyl group in the anion, the sulfonate (S) satisfying the following formula:
0.40≤W(n)/[W(n−1)+W(n)+W(n+1)]≤0.90
wherein n is the number of carbon atoms of the alkyl group in the anion of an alkylbenzenesulfonate accounting for the highest proportion by weight in the sulfonate (S); W(n) is a weight of said alkylbenzenesulfonate; and W(n−1) and W(n+1) are respectively a weight of an alkylbenzenesulfonate containing an anion having an alkyl group with (n−1) carbon atoms and a weight of an alkylbenzenesulfonate containing an anion having an alkyl group with (n+1) carbon atoms.

A polymer [polymer (P)] comprising a plurality of (per)fluoropolyether (PFPE) segments [segments (S.sup.RF)] joined together by hydrogenated (poly)ether segments [segments (S.sup.H)], said polymers (P) having two end groups [groups (E)], each group (E) comprising a hydroxy or a leaving group, with the proviso that the hydrogenated (polytether segment (S.sup.H) is not a segment of formula —CH.sub.2OCH.sub.2 2 OCH.sub.2— is herein disclosed. Disclosed is also a method for the manufacture of polymer (P) and a polymer obtainable by full or partial fluorination of polymer (P). Polymer (P) and polymers obtainable therefrom by full or partial fluorination can be conveniently used in the manufacture of lubricant compositions or of compositions for imparting hydro-/oleo-repellence to substrates. Said polymers can also be used as intermediates for the manufacture of other polymers or block copolymers.

The invention relates to a process for preparing an organic solvent-based dispersion comprising a melt-blended network of an epoxy-functional and/or amino-functional polymer having a polymer-O—Si—O-polymer linkage and a polyolefin (co)polymer having carboxylic acid and/or carboxylic acid anhydride groups, the process comprising the steps of a) forming the melt-blended network from a prepolymer, a silane-functional compound and the polyolefin (co)polymer in the absence of a solvent, b) mixing the melt-blended network with an organic solvent to make the organic solvent-based dispersion, and c) cooling the organic solvent-based dispersion. The invention further relates to a coating composition and to a coated metal substrate.

The invention relates to a process for preparing an organic solvent-based dispersion comprising a melt-blended network of an epoxy-functional and/or amino-functional polymer having a polymer-O—Si—O-polymer linkage and a polyolefin (co)polymer having carboxylic acid and/or carboxylic acid anhydride groups, the process comprising the steps of a) forming the melt-blended network from a prepolymer, a silane-functional compound and the polyolefin (co)polymer in the absence of a solvent, b) mixing the melt-blended network with an organic solvent to make the organic solvent-based dispersion, and c) cooling the organic solvent-based dispersion. The invention further relates to a coating composition and to a coated metal substrate.

Disclosed are copolymer micelles for simultaneous delivery of Cas9 mRNA and guide RNA for Cas9 CRISPR gene editing. Also disclosed are copolymer micelles for simultaneous delivery of a therapeutic or diagnostic nucleic acid and a cross-linking or alkylating anticancer agent.