Patent classifications
C08G2210/00
Method for preventing spontaneous oxidation of antioxidant using aptamer, aptamer-based control of the release rate of active ingredient in the hydrogel, material and use thereof
The present disclosure relates to a method for preventing spontaneous oxidation of an antioxidant, material thereof and uses thereof. More particularly, the present disclosure relates to a method for preventing oxidation of an antioxidant using aptamer specifically binding to its target antioxidant and aptamer-based control of the release rate of active ingredient in the hydrogel. Aptamer having such activity can have versatile applications such as cosmeceuticals and health beverages. As an example, we provide in the present disclosure the establishing method of aptamer targeting for Vitamin C and verification of its prevention of spontaneous oxidation of Vitamin C. We also provide the detailed method for trapping such aptamer-active ingredient complex in the hydrogel. It is expected that an aptamer-trapped hydrogel of the present disclosure has functions of controlling a release rate of the active ingredient through the aptamer-based sensing of specific substance released from the skin according to the skin conditions.
3D Printable Hydrogel Materials
Hydrogel compositions including a polymer uniformly embedded with a loading agent are provided. Also provided are methods for extrusion printing hydrogel compositions to provide extruded hydrogel compositions, which can be crosslinked to provide crosslinked hydrogel structures. Also provided are methods for using crosslinked hydrogel structures in chemical processes.
Method for preparing biomass-based conductive hydrogel by 3D printing
A method for preparing a biomass-based conductive hydrogel by 3D printing is provided. Firstly, a cellulose-based macromonomer, a rosin-based monomer, an acrylic acid monomer and an initiator are mixed in a certain proportion, stirred, and dissolved at 25-70° C. Then, diisocyanate in an amount of 5-10 wt % of a total mass of the monomers is added to the mixed solution and mixed uniformly to prepare a 3D printing photosensitive resin solution. An SLA light-curing 3D printer is used to print a hydrogel precursor 1 with a complex shape. Next, the hydrogel precursor 1 is heated to obtain a hydrogel precursor 2 with a dual-curing network. Finally, the obtained hydrogel precursor 2 is swelled in a 1-15 wt % alkaline solution at 5-60° C. for 0.1-10 hours to obtain the biomass-based conductive hydrogel.
IN SITU-FORMING OF DENDRIMER HYDROGELS USING MICHAEL-ADDITION REACTION
A method of forming a dendrimer hydrogel, the method comprising providing one or more amine end-functioned polyamidoamine (PAMAM) as a first reactant; providing one or more small molecule, polymer, hyperbranched molecule, or dendrimer as a second reactant, wherein the second reactant comprises one or more acrylate groups; and reacting the first reactant with the second reactant by way of conjugate addition. Compositions obtained thereby and uses thereof are also provided.
CROSSLINKING AGENT, PREPARATION PROCESS AND USES THEREOF, HYDROGEL AND BIODEGRADABLE CRYOGEL COMPRISING CROSSLINKING AGENT
The present disclosure provides a crosslinking agent, the preparation process and uses thereof, a hydrogel and a biodegradable cryogel including the crosslinking agent.
HOST-GUEST INTERACTIONS FOR PA SUPERSTRUCTURE FORMATION
The disclosure relates to compositions and superstructures comprising peptide amphiphiles. In some aspects, the disclosure relates to compositions and superstructures comprising host and guest peptide amphiphiles, wherein the host and guest moieties of the peptide amphiphiles interact via non-covalent interactions to form a supramolecular assembly, such a superstructure. In some aspects, the superstructure further comprises a bioactive moiety. Suitable bioactive moieties may be selected to promote cell growth, migration, and/or differentiation.
Ionically modified silicones, compositions, and medical devices formed therefrom
A hydrophilic silicone, compositions comprising the same, and articles comprising the same are shown and described herein. The hydrophilic silicone is an ionically modified silicone compound wherein the compound has a net neutral charge. The hydrophilic silicone compounds may be provided as part of a composition, e.g., a composition suitable for forming a hydrogel, which may be employed to form a film material and even an article (e.g., in a contact lens).
CONDUCTIVE SELF-HEALING NETWORK
Disclosed herein are self-healing conductive network compositions. The networks can contain one or more conductive polymers and one or more supramolecular complexes. The supramolecular complex can be introduced into conductive polymer matrix, resulting in a network of the two components. In this network, the nanostructured conductive polymer gel constructs a 3D network to promote the transport of electrons and mechanically reinforce the network while the supramolecular complex contributes to self-healing property and also conductivity. The networks disclosed herein are useful for various applications such as self-healing electronics, artificial skins, soft robotics and biomimetic prostheses.
ELECTRO-RESPONSIVE HYDROGEL FOR RESERVOIR AND DOWNHOLE APPLICATION
Electro-responsive hydrogel particles are flowed into a first wellbore formed in a subterranean formation. An electric circuit is established between the first wellbore and a second wellbore formed in the subterranean formation. An electric current is applied through the electric circuit, thereby exposing the electro-responsive hydrogel particles to an electric field and causing at least one of swelling or aggregation of the electro-responsive hydrogel particles to form a flow-diverting plug within the subterranean formation. Water is flowed into the first wellbore to increase hydrocarbon production from the second wellbore.
METHOD FOR PRODUCING HYDROGEL, METHOD FOR ENVELOPING ENVELOPMENT TARGET, AND METHOD FOR RELEASING ENVELOPMENT TARGET
Provided is a method for producing a hydrogel, which enables a hydrogel comprising polyethylene glycol to be produced under low peroxidase concentration conditions and physiological conditions. The method for producing a hydrogel involves crosslinking polyethylene glycol having two or more thiol groups using peroxidase in the presence of a phenol compound.