Patent classifications
C08L1/00
INJECTION FORMULATION COMPOSITION CONTAINING MESENCHYMAL STEM CELL-HYDROGEL AND METHOD FOR PREPARING, FREEZING AND DEFROSTING SAME
The present invention relates to a composition containing injectable mesenchymal stem cell-hydrogel and a method of preparing the same. Specifically, in a mesenchymal stem cell-hydrogel composition for injection prepared by a method of the present invention, since stem cells are attached to scaffolds in hydrogel beads, the stem cells are not easily lost or killed after the injection, and thus there is an advantage that an engraftment rate increases since the paracrine effect of the stem cells is continuously exhibited, and the stem cells are gradually released as hydrogel is degraded. In addition, the present invention has an advantage that healthy cells can be used without damages in cell membranes since injection formulation can be prepared without a treatment with proteolytic enzymes, and also a cryopreservation solution is easily removed from the mesenchymal stem cell-hydrogel beads even after freezing and thawing.
ABSORBENT ARTICLE
[Problem] To provide an absorbent article further suppressing occurrence of malodor after absorbing body fluid,
[Solution] An absorbent article comprising a liquid permeable top sheet disposed on a skin surface side, a liquid impermeable back sheet disposed on an external surface side, and at least one water absorbent layer disposed between the top sheet and the back sheet, wherein the water absorbent layer includes a water absorbent resin powder, a deodorizing sheet supporting a polyphenol compound is disposed closer to the skin surface side than the back sheet, and a metal ion is substituted for a part of hydrogen atoms of phenolic hydroxy groups of the polyphenol compound.
ABSORBENT ARTICLE
[Problem] To provide an absorbent article further suppressing occurrence of malodor after absorbing body fluid,
[Solution] An absorbent article comprising a liquid permeable top sheet disposed on a skin surface side, a liquid impermeable back sheet disposed on an external surface side, and at least one water absorbent layer disposed between the top sheet and the back sheet, wherein the water absorbent layer includes a water absorbent resin powder, a deodorizing sheet supporting a polyphenol compound is disposed closer to the skin surface side than the back sheet, and a metal ion is substituted for a part of hydrogen atoms of phenolic hydroxy groups of the polyphenol compound.
COMPOSITE HAVING IMPROVED IN-PLANE PERMEABILITY AND ABSORBENT ARTICLE HAVING IMPROVED FLUID MANAGEMENT
The present disclosure features a composite fabric, including a nonwoven layer including polymeric fibers and/or filaments; a crosslinked cellulose layer including crosslinked cellulose fibers; wherein the crosslinked cellulose layer is positioned opposed to the nonwoven layer (e.g., without an intervening layer different from the crosslinked cellulose layer and the nonwoven layer; in some embodiments, the crosslinked cellulose layer is immediately adjacent to the nonwoven layer); and an interfacial region between the nonwoven layer and the crosslinked cellulose layer, the interfacial region including physically entangled polymeric fibers and/or filaments from the nonwoven layer and crosslinked cellulose fibers from the crosslinked cellulose layer. The nonwoven layer and the crosslinked cellulose layer of the composite fabric are mechanically inseparable in a dry state.
COMPOSITE HAVING IMPROVED IN-PLANE PERMEABILITY AND ABSORBENT ARTICLE HAVING IMPROVED FLUID MANAGEMENT
The present disclosure features a composite fabric, including a nonwoven layer including polymeric fibers and/or filaments; a crosslinked cellulose layer including crosslinked cellulose fibers; wherein the crosslinked cellulose layer is positioned opposed to the nonwoven layer (e.g., without an intervening layer different from the crosslinked cellulose layer and the nonwoven layer; in some embodiments, the crosslinked cellulose layer is immediately adjacent to the nonwoven layer); and an interfacial region between the nonwoven layer and the crosslinked cellulose layer, the interfacial region including physically entangled polymeric fibers and/or filaments from the nonwoven layer and crosslinked cellulose fibers from the crosslinked cellulose layer. The nonwoven layer and the crosslinked cellulose layer of the composite fabric are mechanically inseparable in a dry state.
Sheet
It is an object of the present invention is to provide a sheet containing ultrafine cellulose fibers, which is excellent in transparency and water resistance. The present invention relates to a sheet including cellulose fibers having a fiber width of 1000 nm or less, and polyamine polyamide epihalohydrin, wherein the haze of the sheet is 6% or less.
Sheet
It is an object of the present invention is to provide a sheet containing ultrafine cellulose fibers, which is excellent in transparency and water resistance. The present invention relates to a sheet including cellulose fibers having a fiber width of 1000 nm or less, and polyamine polyamide epihalohydrin, wherein the haze of the sheet is 6% or less.
BIOMATERIAL COMPRISING BACTERIAL CELLULOSE AND PROBIOTICS AND USES THEREOF
The invention relates to biomaterials, which comprise a bacterial cellulose matrix and probiotics entrapped in said bacterial cellulose. The invention also relates to methods for obtaining the biomaterial, as well as uses of the biomaterial in medicine. It also relates to coated food products wherein the coat is composed of said biomaterial wherein the coat acts to prevent the proliferation of undesired bacteria. It also relates to packaged medical devices, wherein the package comprises said biomaterial also preventing growth of pathogenic bacteria.
BIOMATERIAL COMPRISING BACTERIAL CELLULOSE AND PROBIOTICS AND USES THEREOF
The invention relates to biomaterials, which comprise a bacterial cellulose matrix and probiotics entrapped in said bacterial cellulose. The invention also relates to methods for obtaining the biomaterial, as well as uses of the biomaterial in medicine. It also relates to coated food products wherein the coat is composed of said biomaterial wherein the coat acts to prevent the proliferation of undesired bacteria. It also relates to packaged medical devices, wherein the package comprises said biomaterial also preventing growth of pathogenic bacteria.
PROCESS AND APPARATUS FOR MAKING CHANNELED ABSORBENT ARTICLES
A method for making an absorbent article comprising an absorbent core comprising one or more channels, the method comprising the steps of: i. providing a first endless moving surface comprising a plurality of molds, each mold comprising a non-porous insert therein, typically said insert having the inverse shape of said channel(s), wherein the molds are in fluid communication with an under-pressure source except for said insert; ii. feeding a first nonwoven web to said first endless moving surface and over one or more said molds; iii. depositing an absorbent material, comprising cellulose fibers and/or superabsorbent polymer particles, over at least a portion of said nonwoven web; iv. removing said absorbent material from areas of the nonwoven web corresponding to said insert; v. applying a second nonwoven web directly or indirectly over the absorbent material, or folding said first nonwoven web, such to sandwich said absorbent material between upper and lower layers of said nonwoven web(s); vi. joining said upper and lower layers together at least in the areas of the nonwoven web(s) corresponding to the insert to form an absorbent core having one or more channels substantially free of absorbent material; vii. optionally joining an acquisition distribution layer to said absorbent core, typically a skin facing surface of said upper layer; viii. optionally laminating said absorbent core and acquisition distribution layer between a liquid pervious topsheet and a liquid impervious backsheet; wherein step vi. comprises the step of selectively applying a first pressure onto the absorbent core, preferably only, in a central portion thereof and a second pressure, preferably only, along peripheral longitudinal side edges thereof miming opposite and parallel to each other and being outboard of said central portion, said central portion corresponding at least to a region of the core comprising said channel(s), and wherein said first and second pressures are successively applied along a machine direction (MD).