The present disclosure provides reactive quencher dyes that can be used in the detection and/or quantification of desirable target molecules, such as proteins, nucleic acids and various cellular organelles. These dyes are essentially non-fluorescent but are efficient quenchers of various fluorescent dyes. Also, provided are methods of using the dyes, bio-probes incorporating dyes and methods of using the bio-probes. The quencher dyes described herein are modified to provide beneficial properties.

The present disclosure provides reactive quencher dyes that can be used in the detection and/or quantification of desirable target molecules, such as proteins, nucleic acids and various cellular organelles. These dyes are essentially non-fluorescent but are efficient quenchers of various fluorescent dyes. Also, provided are methods of using the dyes, bio-probes incorporating dyes and methods of using the bio-probes. The quencher dyes described herein are modified to provide beneficial properties.

The present disclosure relates to dibenzoxanthene compounds that are efficient quenchers of fluorescence, for example in the far red and near infrared spectrum. Applications using the dibenzoxanthene quenching compounds and methods of making same are also described. Also disclosed is a method of detecting or quantifying a target nucleic acid molecule in a sample by polymerase chain reaction (PCR). The compounds have the following formula (I).

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The present invention relates to new pigment preparations based on metal azo pigments and aliphatic C.sub.10-22 monocarboxylic acids, to processes for their production and their use as a yellow pigment for colouring plastics, and to the use of aliphatic C.sub.10-22 monocarboxylic acids for improving the filtration properties of pigment preparations with at the same time improved colour strengths.

The present invention relates to new pigment preparations based on metal azo pigments and aliphatic C.sub.10-22 monocarboxylic acids, to processes for their production and their use as a yellow pigment for colouring plastics, and to the use of aliphatic C.sub.10-22 monocarboxylic acids for improving the filtration properties of pigment preparations with at the same time improved colour strengths.

A reactive navy to black dye composition comprises component A and component B. Component A is one or more selected from the group consisting of dye compounds of formula (I) and alkali metal salts thereof, and component B is one or more selected from the group consisting of dye compounds of formula (II) and alkali metal salts thereof, based on component A and component B, component A has a mass percentage of 5% to 50%, and component B has a mass percentage of 50% to 95%. The present invention also provides a reactive navy to black dye product comprising the reactive navy to black dye composition. The reactive navy to black dye composition and dye product thereof with properties such as good fastness to washing, high degree of fixation and good build-up, which is suitable for printing and dyeing of nitrogen-containing and/or hydroxyl-containing fiber materials and blended fabrics thereof. ##STR00001##