Patent classifications
C09D189/00
PRIMARY CONTAINERS WITH IMPROVED PROTEIN DRUG STABILITY AND LOWER IMMUNE RESPONSE
A primary drug container is described having an injection-molded thermoplastic wall having an internal surface defining a lumen, a PECVD (plasma-enhanced chemical vapor deposition) drug-contact coating, and a polypeptide composition contained in the lumen. The drug-contact coating is on or adjacent to the internal surface, positioned to contact a fluid in the lumen, and consists essentially of SiOxCyHz. The primary drug container contains between a lower limit of 1,000 and an upper limit of 100,000 particles having effective spherical diameters greater than 2 and no more than 10 micrometers (μm) per mL of solution.
PRIMARY CONTAINERS WITH IMPROVED PROTEIN DRUG STABILITY AND LOWER IMMUNE RESPONSE
A primary drug container is described having an injection-molded thermoplastic wall having an internal surface defining a lumen, a PECVD (plasma-enhanced chemical vapor deposition) drug-contact coating, and a polypeptide composition contained in the lumen. The drug-contact coating is on or adjacent to the internal surface, positioned to contact a fluid in the lumen, and consists essentially of SiOxCyHz. The primary drug container contains between a lower limit of 1,000 and an upper limit of 100,000 particles having effective spherical diameters greater than 2 and no more than 10 micrometers (μm) per mL of solution.
SCALABLE THREE-DIMENSIONAL ELASTIC CONSTRUCT MANUFACTURING
Tissue repair and restoration can be performed using an elastic material formed from tropoelastin. The elastic material can be formed by providing a solution of tropoelastin monomers, applying the solution to a surface, and heating the solution on the surface in absence of a cross-linking agent to enable the tropoelastin monomers to bind to each other to form an elastic material that does not dissociate into tropoelastin monomers when the elastic material is contacted with an aqueous solution.
SCALABLE THREE-DIMENSIONAL ELASTIC CONSTRUCT MANUFACTURING
Tissue repair and restoration can be performed using an elastic material formed from tropoelastin. The elastic material can be formed by providing a solution of tropoelastin monomers, applying the solution to a surface, and heating the solution on the surface in absence of a cross-linking agent to enable the tropoelastin monomers to bind to each other to form an elastic material that does not dissociate into tropoelastin monomers when the elastic material is contacted with an aqueous solution.
PROTEIN POLYURETHANE ALLOYS AND LAYERED MATERIALS INCLUDING THE SAME
Protein polyurethane alloys including one or more proteins dissolved within one or more polyurethanes. The protein polyurethane alloy may have one or more mechanical properties that are superior to the polyurethane in the absence of protein. The protein polyurethane alloys may be incorporated into a layered material including one or more protein polyurethane alloy layers.
PROTEIN POLYURETHANE ALLOYS AND LAYERED MATERIALS INCLUDING THE SAME
Protein polyurethane alloys including one or more proteins dissolved within one or more polyurethanes. The protein polyurethane alloy may have one or more mechanical properties that are superior to the polyurethane in the absence of protein. The protein polyurethane alloys may be incorporated into a layered material including one or more protein polyurethane alloy layers.
PROTEIN DISPERSIONS
The present invention relates to a method for preparing a plant-based protein hydrogel slurry, and to a method for preparing a plant-based structured material (e.g. a film, a casting, a moulding etc.) from the plant-based protein hydrogel slurry.
PROTEIN DISPERSIONS
The present invention relates to a method for preparing a plant-based protein hydrogel slurry, and to a method for preparing a plant-based structured material (e.g. a film, a casting, a moulding etc.) from the plant-based protein hydrogel slurry.
METHOD FOR PREPARING SILK FIBROIN FILM BY WET FILM COATING
Provided is a method for preparing silk fibroin film by wet film coating, including: (1) scrape coating a regenerative silk fibroin wet films on selected substrates, drying, to obtain regenerated silk fibroin films after drying; (2) Putting the dried silk fibroin film in water, so that the silk fibroin film can be detached peeled from the substrate after subsequent drying; and (3) drying Exfoliate the further dried silk fibroin film and peeling from the substrate. It is the first time to realize the preparation of free-standing fibroin film by wet film coating. The silk fibroin film has properties of ultra-thin, flexible, transparent, permeable, excellent biocompatibility, etc., thus being suitable for applications in flexible electronics, such as epidermal electronics. In addition, the method is not only suitable for industrial batch production of the fibroin film, but also matched with the existing film processing technologies such as roll-to-roll and nano-imprint.
Coatings containing polymer modified enzyme for stable self-cleaning of organic stains
Bioactive coatings that are stabilized against inactivation by weathering are provided including a base associated with a chemically modified enzyme, and, optionally a first polyoxyethylene present in the base and independent of the enzyme. The coatings are optionally overlayered onto a substrate to form an active coating facilitating the removal of organic stains or organic material from food, insects, or the environment.