According to one embodiment of the present invention, a multiplex PCR device is disclosed. The multiplex PCR device comprises a multiplex PCR chip simultaneously carrying a plurality of mutually different nucleic acid molecules, and the invention may be characterised in that, attached spaced apart from each other on the multiplex PCR chip, there are a plurality of probes used for hybridization reactions whereby hybridization takes place specifically with mutually different amplified sequences of the nucleic acid molecules.

A system, apparatus, and method using carbon monoxide for treatment of platelets, and optionally other blood components and/or whole blood, allowing extended storage and increased viability of the stored blood platelets in vivo. The system allows an efficient use of the stored platelets by dividing the platelets into a population with a short residual lifetime for immediate use and a population that can remain in storage for longer. The storage apparatus enables safe platelet preservation and is equipped with an alarm to detect CO leakage.

An observation system includes an illumination unit including a light source from which emits an illumination light including light of a plurality of colors, and light receiving unit including an optical sensor which acquires a light intensity. The illumination unit emits the illumination light for a culture vessel so that the illumination light travels from a first side to a second side of the culture vessel, the first side and the second side being defined by interposing a culture medium. The light receiving unit receives, on the first side, light emitted from the illumination unit, entering the culture vessel from the first side, reflected at the second side, and transmitted through the culture medium, and acquires a light intensity for each color in the received light for calculation of a pH value of the culture medium.

A cell culture container may include an inlet through which a fluid is supplied, an outlet through which a fluid is discharged, and a flow path configured to connect the inlet to the outlet and accommodate a cell culture substrate containing gold nanoparticles and capable of being denatured by heating.

Methods and systems for preparing clonal cell populations are described. In some instances the disclosed methods comprise: a) identifying and selecting a cell based on its position on a surface or in a container, where the selection is not based on whether the cell comprises an exogenous label or an expressed reporter; b) photoablating all non-selected cells on the surface or in the container; and c) growing a clonal population of the selected cell.

A method of cultivating algal cells of an algae belonging to a class selected from Chlorophyceae, Euglenophyceae, Bacillariophyceae and Haptophyceae includes: irradiating the algal cells with an artificial light having a ratio of (i) photon flux density in a wavelength range of 520-630 nm to (ii) photosynthetic photon flux density, that is 65% or more; and measuring a condition of the algal cells and/or a condition of an algal cell culture provided by cultivating the algal cells. Irradiation and non-irradiation of the algal cells with the artificial light are switched, or the photon flux density in the wavelength range of 520-630 nm is changed, according to the measured condition of the algal cells and/or the measured condition of the algal cell culture.

Photobioreactor devices and units for the production of biomass and remediation of environmental contamination are provided. The bioreactor devices comprise (i) a photobioreactor unit comprising a first membrane layer and a second membrane layer, the two membrane layers arranged such that at least a portion of the first membrane layer is directly bonded to at least a portion of the second membrane layer in order to form a defined boundary around non-bonded portions of the first and second membrane layers, thereby defining the photobioreactor unit capable of containing a fluid, wherein at least one of the first and second layers is translucent, and wherein at least a part of the first and second membrane layers is permeable to gases. The permeability coefficient of oxygen through the first and/or second membrane layer is suitably not less than about 100 Barrer, typically not less than about 300 Barrer, and suitably not less than about 500 Barrer. The photobioreactor unit also comprises an inlet and an outlet port to enable the fluid to circulate through said unit. Systems comprising the devices are provided as well as methods of using the devices for the production of biomass, remediation of wastewater and removal of atmospheric pollutants.

An algae cultivation system may include: a plurality of panels within a cultivation container, positioned along a first axis perpendicular to the gravitational force, wherein a cultivation volume is created between each pair of panels, and wherein the cultivation volumes are fluidly coupled so as to allow horizontal flow therebetween along the first axis; at least one first sparger, to distribute a first fluid into the container at a first operating flow rate; at least one second sparger, to distribute a second fluid into the container at a second operating flow rate; and at least one controller, to control the first operating flow rate and the second operating flow rate. The first operating flow rate may be adapted to allow turbulent mixing the algae in the cultivation container, and the second operating flow rate may be adapted to allow assimilation of materials in a liquid in the cultivation container.

The instant disclosure relates to the field of algal cultivation and production of high value biochemical products thereof. Particularly, the present disclosure relates to a cultivation method comprising the application of red light/far-red light in life cycle management of green microalgae, particularly Haematococcus, including induction of intense vegetative growth, and enhancement of productivity. The present method is simple, commercially scalable and cost-effective, achieves enhanced productivity, and requires shorter time duration, amongst other advantages.

Provided is a culture device, including: a culture tank (110) configured to store an object liquid that is a culture solution having suspended therein an object; a screen (210) made of a metal, the screen including a main body (212) and a plurality of through holes (slits (214)) passing through the main body (212) from a front surface (212a) thereof to a back surface (212b) thereof; a spray portion (220) configured to spray the object liquid stored in the culture tank onto the front surface of the main body (212); an accommodation portion (240) surrounding the back surface (212b) of the main body (212) and configured to accommodate the culture solution having passed through the through holes; a UV light irradiation portion (250) arranged in the accommodation portion (240) and configured to radiate UV light; and a return portion (290) configured to return the culture solution in the accommodation portion (240) to the culture tank.