C12M31/00

CELL SAMPLE EVALUATION METHOD, CELL SAMPLE EVALUATION APPARATUS, AND CULTURE STATE ANALYSIS APPARATUS

A cell sample evaluation apparatus includes an evaluation light irradiation unit for irradiating an irradiation region set in a culture region of a plurality of cells in an object cell sample with evaluation light having a wavelength in a mid-infrared region under a predetermined irradiation condition, a dead cell number measurement unit for measuring a dead cell number generated according to an irradiation amount of the evaluation light in the irradiation region of the object cell sample, and a culture state analysis unit for evaluating a culture state of the object cell sample by obtaining an object correlation between the irradiation amount of the evaluation light and the dead cell number for the object cell sample and comparing a reference correlation between the irradiation amount of the evaluation light and the dead cell number for a reference cell sample and the object correlation.

PRODUCTION EQUIPMENT AND FACILITIES FOR UNICELLULAR MICROORGANISMS, MICROORGANISM COMMUNITIES, MULTICELLULAR PLANT AND ANIMAL CELLS AND AQUATIC ORGANISMS
20240400956 · 2024-12-05 ·

Production equipment for production of biological material, comprising a bioreactor 12, 3 for the cultivation and production of unicellular microorganisms and communities of microorganisms as well as multicellular aquatic plant and animal organisms. The bioreactor has at least one space for the proliferation 21 of unicellular microorganisms, communities of microorganisms, multicellular aquatic plants and animals, which space is in communication with a device 23 for cultivating, transporting and harvesting said microorganisms or aquatic organisms, comprising a pipe chain conveyor.

SELECTIVE MEMBRANE-DRIVEN GAS TRANSFER DEVICE AND METHODS
20250027016 · 2025-01-23 · ·

Described herein are methods and devices for selective membrane-driven gas transfer.

THERMOCHROMIC SENSING DEVICES, SYSTEMS, AND METHODS
20170191020 · 2017-07-06 ·

A test vessel includes one or more test locations configured to contain a medium suitable for culturing a live substance. A thermochromic material is thermally coupled to the one or more test locations. The thermochromic material is configured to exhibit a spectral shift in light emanating from the thermochromic material in response to an increase or decrease in energy conversion by the live substance that causes a change in temperature of the thermochromic material.

SYSTEM FOR IDENTIFYING AND PICKING SPECTRALLY DISTINCT COLONIES

System, including methods and apparatus, for identifying and picking spectrally distinct colonies. In an exemplary method, a filter may be received in an optical path extending from a light source to a grayscale image detector. The filter may be configured to increase an intensity difference between a first type of colony and a spectrally distinct second type of colony. Colonies including both types may be received in the optical path. An image of the colonies may be obtained with the grayscale image detector. At least one of the types of colony may be identified in the image. One or more colonies of the at least one type may be picked robotically.

Optically sensitive cell network

A neural network is disclosed. The neural network comprises a plurality of optogenetically modified neural cells being three-dimensionally distributed in a hydrogel medium and being disconnected from any solid support having a shear modulus above 1 GPa.

CELL CULTURE OBSERVATION DEVICE AND METHOD
20170158998 · 2017-06-08 · ·

A cell culture observation device and a cell culture observation method which observe a plurality of culture containers and perform operations for each culture container capture an image without blurring caused by the operations for the culture container and improve the throughput of processing for the plurality of culture containers. The cell culture observation device includes a cell observation unit 30 that observes cells in each of a plurality of culture containers in which the cells are cultured, an operating unit 20 that performs a plurality of operations for each of the culture containers, and an operation content determination unit 41 that determines the content of an operation which can be performed for culture containers other than a culture container to be observed while the culture container to be observed is being observed among the plurality of operations.

MULTIPLEX PCR CHIP AND MULTIPLEX PCR DEVICE COMPRISING SAME
20170151571 · 2017-06-01 ·

According to one embodiment of the present invention, a multiplex PCR device is disclosed. The multiplex PCR device comprises a multiplex PCR chip simultaneously carrying a plurality of mutually different nucleic acid molecules, and the invention may be characterised in that, attached spaced apart from each other on the multiplex PCR chip, there are a plurality of probes used for hybridization reactions whereby hybridization takes place specifically with mutually different amplified sequences of the nucleic acid molecules.

CELL CULTURE CONTAINER, CELL IMAGING METHOD, AND CELL CULTURE SYSTEM
20170145370 · 2017-05-25 ·

A cell culture container includes a container that houses therein a liquid mixture including one or more cells and a culture solution, an irradiator that irradiates the liquid mixture with light, and an image sensor that receives transmitted light that is the light that has been emitted from the irradiator and has passed through the liquid mixture. The light emitted from the irradiator includes a plurality of rays, and the plurality of rays do not cross each other between the irradiator and the image sensor.

METHOD FOR DETECTING THE PRESENCE OR ABSENCE OF BIOLOGICAL PARTICLES
20170137772 · 2017-05-18 · ·

A method detects the presence or absence of at least one first inhibition zone having a culture of biological particles on a culture medium in the presence of a chemical agent. The method of detection has a first step of seeding the culture medium with the biological particles, a second step in which the culture medium receives the chemical agent, a third step of incubation of the culture medium, and a fourth step of measurement of the first inhibition zone of the culture medium, which includes a first phase of taking an image of the first inhibition zone by ombroscopy.