Patent classifications
C12M37/00
Sterile packaging unit and method for producing same
A sterile packaging unit includes a disposable bioprocessing component (20) and a packaging (30). The disposable bioprocessing component (20) has a component wall that encloses a processing space and on which is secured a sensor system (40) with at least one sensor head (T, P, I, L, D) and with attached sensor electronics (42) that include a memory unit (44). The packaging (30) hermetically encloses the disposable bioprocessing component (20) and has a flexible packaging wall. The disposable bioprocessing component (20) and the packaging (30) are sterilized by being jointly irradiated with ionizing radiation. The sensor electronics (42) are connected electrically to a contact unit (34) extending through the packaging wall.
BIOLOGICAL PROCESSING ASSEMBLY
The present invention relates to a biological (eg cell) processing assembly comprising an aseptic chamber with apertures adapted for gloves to fit and an incubation chamber connectable to aseptic chamber with transfer hatches, doors secured by multi-walls and inflatable seals, stepped collars for tight closure of doors and closed interaction between the chambers. From the aseptic chamber it can be reached through into incubation chamber. There is a docking spigot on outlet wall to interact with stepped collar to define transfer port between the chambers and a disinfectant delivery device to disinfect transfer port.
CELL CULTURE OR INDUCTION METHOD
Provided is a cell culture or induction method including subjecting the cells to culture or induction in a sealed system.
All-in-One Distributed and Portable Fermentation Systems with Platform for Holding Same
Systems and methods for producing microbe-based compositions that can be used in the oil and gas industry, environmental cleanup, as well as for other applications are provided. More specifically, a moveable all-in-one system for producing microorganisms and/or metabolites is provided. The system can be delivered to a fermentation site in a ready-to-use state, such that on-site fermentation can be initiated in a short period of time.
DRYING SUPPRESSION DEVICE AND CELL CULTURE KIT
A drying suppression device including: a main body housing a well plate; and an openable/closable lid provided on the main body, the main body including: a holder section that holds the well plate; a liquid storage tank that stores liquid; and a support section that supports the holder while keeping the holder section away from an inner bottom surface of the liquid storage tank, wherein, with the lid being closed, an inner space surrounded by the liquid storage tank and the lid communicate with an outside space.
CULTURE DEVICE
This culture device comprises: a duct having an inner wall surface which faces a culture space, and a mounting surface which faces the portion to be mounted to of the inner surface, the mounting surface being mounted to the portion to be mounted to, and an air passage being formed with the inner wall surface; and a microbial light source provided within the passage. A protrusion which comes into close contact with the mounting surface, and which protrudes towards the mounting surface, is formed on the portion to be mounted to, or a protrusion which comes into close contact with the portion to be mounted to and which protrudes towards the portion to be mounted to is formed on the mounting surface.
SYSTEMS AND METHODS FOR CELL PROCESSING
Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.
FLUID CONNECTOR
Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.
ASEPTIC CELL PROCESSING AND PRODUCTION WITH NO CHEMICAL BIOCIDES
A method and apparatus of aseptic processing and production of cells in a non-sterile enclosure apparatus without chemical biocides is disclosed, by controlling the level of humidity throughout the enclosure to 25% relative humidity (RH) or less, and preferably 20% or 15% or less RH. In addition, the temperature is controlled to 37° C., and consistent gas flow is maintained the enclosure. Colony forming units from microbial contamination detected by environmental monitoring within the enclosure are significantly reduced in this method.
AUTOMATED DEVICE FOR PRODUCTION OF BIOENGINEERED TISSUES AND ORGANS BASED ON DECELLULARIZATION AND RECELLULARIZATION
The present invention discloses an automated device for tissue and organ engineering. The device comprises a main chamber for performing decellularization, tissue sterilization, and recellularization and a set of solution and medium chambers, which provide solutions and medium for the decellularization and recellularization processes, respectively, in a continuous closed circuit. The device further comprises a sterilizing system for self-sterilization of the automated device. The device further comprises a user interface to input steps of protocols for tissue or organ engineering. The device further comprises a controller configured to control valves and pumps, which control and direct the flow of solutions and medium based on the steps of protocols, thereby automating the processes of decellularization, tissue sterilization, recellularization and self-sterilization. All parts of the device are installed in one single body in a fully integrated manner, in one example, which makes the device ready to use. The device minimizes the user intervention and enhances sterility, reproducibility, and efficiency.