A mixing apparatus for reconstituting a powdered cell culture media. The apparatus includes at least one fluid chamber, an influent port at a lower portion of the fluid chamber. The apparatus further includes a geometric fluid flow aid positioned in the fluid chamber and an effluent port at the top of the fluid chamber. A powdered cell culture media is provided in the fluid to be mixed with a fluid provided by the influent port. The effluent port is configured to allow reconstituted media to exit the fluid chamber.

A target particle transferring device is disclosed, which comprises: (a) a substrate with a thickness of T and a width of W, having top and bottom portions, the top portion having a top surface and the bottom portion having a bottom surface; (b) a notch structure formed in the bottom portion of the substrate, comprising: a groove with a width of W1, located at a distance oft below the top surface of the substrate, wherein the groove is formed in the bottom portion from the bottom surface extending toward the top portion; and (c) a target substrate portion with a width of W2 and a thickness of T, located in the top and bottom portions of the substrate and being surrounded by the groove. Methods of transferring a target particle from one device to another is also disclosed.

This invention concerns methods of packaging and shipping stem cells. Also disclosed are related package products.

Provided is a method for decomposing peracetic acid and a method for culturing microorganisms using the decomposition method. The cultivation of microorganisms using the method of the present invention allows an effective removal of the peracetic acid used in a culture medium for sterilization.

A pressurized appliance comprising, a tank, suitable for receiving liquid contents, a cover, suitable for sealing the tank in a closed position, said cover comprising a sampling tip, said tip comprising a cannula capable of being in contact with the contents when the cover is in the closed position, the sampling tip comprising at least one sealable orifice making it possible, when the cover is in its closed position and said orifice is a through-orifice, to ensure a pressure equilibrium between the inside of the cannula and the inside of the tank, and when the cover is in its closed position and said orifice is sealed, to sample the contents via the cannula.

The invention relates to an actuator apparatus (1) for generating the motion of a tool, in particular for the work on biological cell material, which provides at least one electrically controlled actuator element (3), a motion section (3a), at which a tool can be arranged and which is linked to the at least one actuator element, an electrical control device (11) for controlling the at least one actuator element, an electrical measurement device (12), which is configured to perform a measuring method for measuring at least one electrical capacitance quantity of the at least one actuator element, wherein the capacitance quantity is usable to provide information on the status of the actuator apparatus. Further, a corresponding method for obtaining and utilizing said information on the actuator apparatus is provided.

A microfluidic dual-well device is disclosed. The device comprises: (a) a first substrate having a first end, a second end, and a culture microwell forming portion; (b) a plurality of culture microwells; (c) a second substrate having a first end, a second end, and a capture microwell forming portion, the two ends of the second substrate being respectively bounded to the two ends of the first substrate; (d) a plurality of capture microwells; (e) a microfluidic channel; (f) a microfluidic inlet port; and (g) a microfluidic outlet port; wherein the microfluidic channel is in fluidic connections with the culture microwells, the capture microwells, and the inlet and outlet ports. Methods of capturing and transferring a single cell or a single cell colony for culture, and method of transferring a target cell from a polydimethylsiloxane (PDMS) structure of culture microwells to a culture plate for culture are also disclosed.

A test plate processing system for processing multiple test plates, comprising one or more software controlled processing devices, a liquid handler configured to place a predetermined amount of a test substance on the plate when the cover is in the first position, a software controlled test plate storage device having one or more test plate storage modules configured to house a plurality of test plates, and a software controlled test plate transport device configured to move one or more test plates to and from the test plate storage device. Each of the processing devices can have a working surface and a lifting mechanism configured to move a cover of the test plate between a first position and a second position relative to a plating surface of the test plate, wherein the cover is further away from the plating surface in the first position than in the second position.

A test plate processing system for processing multiple test plates, comprising one or more software controlled processing devices, a liquid handler configured to place a predetermined amount of a test substance on the plate when the cover is in the first position, a software controlled test plate storage device having one or more test plate storage modules configured to house a plurality of test plates, and a software controlled test plate transport device configured to move one or more test plates to and from the test plate storage device. Each of the processing devices can have a working surface and a lifting mechanism configured to move a cover of the test plate between a first position and a second position relative to a plating surface of the test plate, wherein the cover is further away from the plating surface in the first position than in the second position.