A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).

A method for tanning an animal substrate comprising the steps: i) agitating the animal substrate with a chromium-free tanning agent; and ii) agitating the animal substrate with a tanning agent having an oxazolidine group; wherein at least some of the agitation is performed in the presence of a solid particulate material having an average particle size of from 1 to 500 mm.

A method for tanning an animal substrate comprising the steps: i) agitating the animal substrate with a chromium-free tanning agent; and ii) agitating the animal substrate with a tanning agent having an oxazolidine group; wherein at least some of the agitation is performed in the presence of a solid particulate material having an average particle size of from 1 to 500 mm.

The invention relates to an improved method and apparatus for the treatment of animal skin substrates which employs a multiplicity of solid particles. There is disclosed an apparatus for treating one or more animal skin substrates with a multiplicity of solid particles and treatment liquor comprising: a rotatably mounted drum comprising an internal volume having a first portion defining a treatment volume for retaining said animal substrates and a second portion defining a collecting volume; one or more inlets for introducing solid particles and treatment liquor into said treatment volume; a partition separating said treatment volume from said collecting volume wherein said partition allows free passage of solid particles from the treatment volume to the collecting volume and prevents the passage of the substrates therethrough; a circulation path for conveying said solid particles from the collecting volume to the treatment volume; and a pumping device arranged to pump solid particles and said treatment liquor along a portion of said circulation path.

The invention relates to an improved method and apparatus for the treatment of animal skin substrates which employs a multiplicity of solid particles. There is disclosed an apparatus for treating one or more animal skin substrates with a multiplicity of solid particles and treatment liquor comprising: a rotatably mounted drum comprising an internal volume having a first portion defining a treatment volume for retaining said animal substrates and a second portion defining a collecting volume; one or more inlets for introducing solid particles and treatment liquor into said treatment volume; a partition separating said treatment volume from said collecting volume wherein said partition allows free passage of solid particles from the treatment volume to the collecting volume and prevents the passage of the substrates therethrough; a circulation path for conveying said solid particles from the collecting volume to the treatment volume; and a pumping device arranged to pump solid particles and said treatment liquor along a portion of said circulation path.

A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).

A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).

A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).

A tissue modification apparatus includes at least a first plurality of grippers aligned in a plane adapted to secure a first edge of a patch of tissue. The plurality of grippers are each secured to a first force actuator. The first plurality of grippers are each adapted to pivot relative to the first force actuator about an axis perpendicular to the plane. In some cases, a plurality of grippers are attached to a force actuator by a passive force transfer mechanism. In some cases, individual force actuators are attached by pivoted connections to individual grippers. Methods of treating tissue can secure tensioned tissue to a frame to retain the tension during a treatment (e.g., cross-linking the tissue with a chemical cross-linker).

The invention relates to a method and the production of natural leathers from pieces of natural leather torn into different-sized fibers which are sorted and placed, once they have been mixed with a binder, in successive layers (6, 7 and 8) on a support sheet (9) provided with filaments crossing the different layers. The support sheet (9) and filaments (10) are extracted once the binder substance has cured.