A first sidewall includes a pair of threaded bosses nesting within corresponding cavities in a second sidewall. Bolts extend through the cavities into threaded engagement with the bosses to secure the sidewalls with one another. One of the bosses supports a knurled or toothed wheel for engagement with a parachute cord. A pivotable pawl having a knurled or toothed surface is pivotably supported on a shaft anchored in the sidewalls and spring biased toward the wheel into engagement with the parachute cord to prevent translation of the parachute cord in one direction. The other boss supports a hook or cord for anchoring the tie down to an anchor.

A first sidewall includes a pair of threaded bosses nesting within corresponding cavities in a second sidewall. Bolts extend through the cavities into threaded engagement with the bosses to secure the sidewalls with one another. One of the bosses supports a knurled or toothed wheel for engagement with a parachute cord. A pivotable pawl having a knurled or toothed surface is pivotably supported on a shaft anchored in the sidewalls and spring biased toward the wheel into engagement with the parachute cord to prevent translation of the parachute cord in one direction. The other boss supports a hook or cord for anchoring the tie down to an anchor.

Buckle component (1) having a belt receiving opening (2) and a frame (3) enclosing the belt receiving opening (2), and a bar (4) about which the belt (5) is guidable, wherein the bar (4) is fastened to the frame (3), in a manner crossing, in particular completely crossing, the belt receiving opening (2), by at least one fastening device (6, 7) of the buckle component (1). The bar (4) is fastened to the frame by plastic deformation of the bar (4) and/or of at least one of the fastening devices (6, 7) and/or of the frame (3).

The present invention relates to an ornamental connector for connecting an ornamental item to and elongate flexible member such as a strap, belt or chain. The ornamental connector includes abase including an aperture a recess for receiving the elongate flexible member, as well as an engaging arrangement for removably connecting an ornamental item. The ornamental connector can further include a locking arrangement for locking the ornamental connector to the base. The ornamental connector can further include a holding arrangement for preventing sliding movement of the ornamental connector along the elongate flexible member.

A buckle structure is adapted to connect a strap. The buckle structure has a connecting port. The connecting port has a connecting member for connecting the strap. An extending portion extends from a side of the connecting port. The extending portion has an opening for the strap to pass through. The strap passes through the opening to enter the connecting port and connect the connecting member.

A wearable electronic device assembly has a strap attached to the device for attaching the device to a wearer, and a connector for securing two overlapping end regions of the strap together. The connector has first and second parts configured to be secured together with the two overlapping end regions of the strap extending between them, to secure the two end regions together. The first part has a projection arranged to extend through or adjacent to the strap. The second part has a main body having an aperture to receive the projection of the first part, and a securement part movable with respect to the main body between a released position and a securement position. The projection is retained in the aperture to secure the first part of the connector to the second part of the connector.

A positionable connector assembly comprises a base, a connector operatively connected to the base, a friction member positioned between the base and the connector, and a biasing member operatively connected to the connector and configured and arranged to bias the connector toward the friction member.

There is provided a tactile presentation device capable of realizing easier wearing/removal and contact of a tactile stimulation unit in an appropriate position. The tactile presentation device is provided with an attaching unit to a back plate of a chair, and a wearing belt portion to a body provided so as to be extendable and contractable on the attaching unit, in which one or more first tactile stimulation units are provided on the attaching unit, and one or more second tactile stimulation units are provided on the wearing belt portion.

The subject invention pertains to biomarkers for identifying a subject as having high risk of the development PE. The biomarkers presented herein include miRNAs, post-translational modification of histone proteins, amount, expression and/or activity of histone or DNA modifying enzymes and methylation of sites in the genomic DNA. In certain embodiments, increased miR-17, increased acetylation of H4 histone protein, decreased amount, expression and/or activity of HDACS mRNA or protein or increased methylation of DNA at the genomic site CYP19A1 in the blood, serum or plasma of a subject compared to that of a control subject is used to predict the development of PE in the subject. The invention also provides kits and reagents to conduct assays to quantify biomarkers described herein. The invention further provides the methods of treating and/or managing PE in a subject identified as having a high risk of the development of PE.

The subject invention pertains to biomarkers for identifying a subject as having high risk of the development PE. The biomarkers presented herein include miRNAs, post-translational modification of histone proteins, amount, expression and/or activity of histone or DNA modifying enzymes and methylation of sites in the genomic DNA. In certain embodiments, increased miR-17, increased acetylation of H4 histone protein, decreased amount, expression and/or activity of HDACS mRNA or protein or increased methylation of DNA at the genomic site CYP19A1 in the blood, serum or plasma of a subject compared to that of a control subject is used to predict the development of PE in the subject. The invention also provides kits and reagents to conduct assays to quantify biomarkers described herein. The invention further provides the methods of treating and/or managing PE in a subject identified as having a high risk of the development of PE.