A suture-free stent graft is disclosed including a woven graft tube having woven extensions extending from an outer face of the woven graft tube. Each of the woven extensions is integrally woven with the woven graft tube such that warp from the woven graft tube is de-interlaced from at a first end and re-interlaced at a second end. Supplemental warp is interlaced into the woven graft tube in replacement of the deinterlaced warp so as to maintain weave density in the woven graft tube under the woven extensions. The woven extensions and portions of the woven graft tube disposed directly under the woven extension have independent weft from one another. A suture-free stent graft construct is disclosed including the suture-free stent graft and at least one stent wire disposed about the suture-free stent graft, at least partially disposed between the woven graft tube and the woven extensions at securement sites.

The method of encapsulating an active protein includes (a) establishing a primary mesenchymal cell culture; (b) maintaining the cell culture established until the culture surface is fully covered by the cultured cells; (c) obtaining a culture fluid from the cultured cells; (d) purifying the culture fluid from cell debris and suspended cells; (e) transferring the upper liquid phase to a new vessel; (f) gently mixing the purified liquid phase with an aqueous solution of polyvinyl alcohol; (g) adding ethyl alcohol to the mixture while stirring continuously; and (h) depositing on the collector surface by electro spinning or electrospraying. The invention includes an immunomodulating composition containing an active protein and a polymer, wherein the active protein is a fibrous, fully water-soluble material containing proteins released by mesenchymal cells, including CCL2.

This innovation discloses a bioactive and biocompatible implant that comprises a fibrillar membrane of an electrospun polymeric matrix, where the matrix features a structural reinforcement with gold nanoparticles that allows the propagation of bioelectrical activity of the cardiac tissue, restoring the conductivity of the bioelectrical stimuli, given the electroconductive capacity provided by its components.

The presently disclosed composition and methods are provided for an in situ forming nanofiber-hydrogel composite, which is formed using non-covalent binding schemes between the fiber surface and hydrogel-forming polymers. A method for healing a soft tissue defect can include applying the said composite material to a soft tissue defect.

A staple cartridge assembly for use with a surgical stapling instrument includes a staple cartridge including a plurality of staples and a cartridge deck. The staple cartridge assembly also includes a compressible adjunct positionable against the cartridge deck, wherein the staples are deployable into tissue captured against the compressible adjunct, and wherein the compressible adjunct comprises a first biocompatible layer comprising a first portion, a second biocompatible layer comprising a second portion, and crossed spacer fibers extending between the first portion and the second portion.

An apparatus, and method, for a garment embedded secretion analysis. The system includes a liner that includes at least a sensor from a plurality of sensors. The system also includes a computing device embedded in the liner and communicatively connected to the at least a sensor, where the computing device includes a detection module configured to extract at least a biological sample from the user, authenticate the user as a function of the biological sample and a biological data of the user, detect a condition datum as a function of the biological sample and biological data of the user and determine an event datum as a function of the condition datum. Computing device also includes a safety module configured to receive the event datum and generate an alert datum as a function of the event datum.

Nonwoven fabrics having liquid barrier properties are provided. The nonwoven fabrics may include one or more nonwoven layers, in which one or more of the nonwoven layers may include a liquid-barrier-enhancing-additive (LBEA) comprising an amide. The nonwoven fabrics may be suitable for use in a wide variety of liquid barrier applications, including facemasks, surgical gowns, surgical drapes, lab coats, and barrier components of absorbent articles (e.g., barrier leg cuffs).

An elastomeric bicomponent fiber, including at least one sheath and a core, with non-blocking properties and a garment-like feel is provided. The core includes an elastomer and a secondary amide, and the sheath includes a non-elastomeric polyethylene. Further, the sheath can be present as a small portion of the total elastomeric composition, and the secondary amide can be present as a small portion of the core, while forming a bicomponent fiber with non-blocking properties and a garment-like feel.

Implantable adjuncts for use with a surgical instrument are disclosed. The implantable adjunct includes a first mesh positioned about a first side of the longitudinal knife slot and a second mesh positioned about a second side of the longitudinal knife slot such that the first and second meshes define a gap substantially aligned with the longitudinal knife slot of the staple cartridge body.

A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. The apparatus includes a member to pull the soft tissue implant into a femoral tunnel. The member includes a suture having first and second ends which are passed through first and second openings associated with the longitudinal passage to form a pair of loops. A collapsible tube is positioned about the suture Application of tension onto the suture construction causes retraction of the soft tissue implant into the femoral tunnel and the collapse of the tube to form an anchor.