A targeted drug delivery device comprises a brush for use in delivery of one or more therapeutic agents during surgical procedures, including but not limited to, heart, chest, abdominal, brain, limb, vascular, eye, organ transplantation surgery or cancer surgical treatment. The therapeutic agent is selected from the group consisting of genetically engineered vectors or cells, proteins, stem cells, small molecule pharmaceuticals, drugs or biologics. Methods of treating diseases comprising delivering at least one therapeutic agent to a patient's organs or tissues using any one of the targeted drug delivery devices are disclosed.

An apparatus including but not limited to a plunger driven dispenser comprising a handle having an inner section and an outer section and a top; a storage chamber formed inside of the inner section the contains a highly viscous product, wherein the storage chamber has a tapered opening at the bottom and an aperture in the top of the storage chamber, wherein the aperture further comprises a coned tip surrounding the aperture; a syringe and plunger formed inside of the outer section that fits into the storage chamber and extrudes the cosmetic product through the coned tip aperture under pressure applied to the plunger; and an aperture in the top that receives cosmetic product from the storage chamber through the coned tip aperture and a spike to seal the storage chamber.

An automatic suction cleaning structure is disclosed. The automatic suction cleaning structure is disposed on a cleaner body. The automatic suction cleaning structure comprises a fixing base (1) connected to the cleaner body and a number of brush heads (2) arranged on the fixing base (1). The brush heads (2) are made of silica gel, and are of a hexagon shape and a hollow structure. The number of brush heads (2) are arranged on the fixing base (1) in an array and distributed in a cellular arrangement. By arranging the cellular brush heads (2) of a hollow structure and utilizing a suction force produced by the tightly-attached brush heads (2) during use, dirt on the skin surface is sucked automatically by means of a sucking disc principle in a process of contact with the skin, to allow more thorough cleaning. A cleaner is also provided.

The present disclosure generally relates to oral care systems and devices. An oral care system includes a container defining an interior portion. The container includes a repository provided within the interior portion and configured to hold a fluid, and a barrier configured to maintain the fluid separate from the interior portion. The barrier is configured to be breached to expose the interior portion to the fluid. The system further includes a tube configured to slide in the interior portion of the container. The tube includes a distal end configured to breach the barrier when the tube is moved in a direction of the fluid in the repository.

An oral fluid delivery device includes a housing forming at least one cavity. The cavity includes at least two reservoirs, a first reservoir and a second reservoir. The device also includes an elongated neck with a distal end having at least one distal opening for passage of a fluid, a proximal end, and a channel fluidly connected to the distal opening. The device also includes a cap at the proximal end of the elongated neck. The cap includes at least one aperture aligned with the channel of the elongated neck and is rotatably coupled to the housing such that rotating the cap relative to the housing selectively aligns the aperture with a first reservoir opening to provide fluid communication between the first reservoir and the channel, or aligns the aperture with a second reservoir opening to provide fluid communication between the second reservoir and the channel.

Disclosed is a makeup applicator with interchangeable brush and sponge heads. An embodiment may include two heads (e.g., brush, sponge, etc.) that are replaceable and/or interchangeable using a reversible connector. The applicator preferably includes a silicone stalk with a connector projecting from each end. Each connector is preferably composed of silicone and includes a rim adapted to securely engage the brush and/or sponge heads. Preferably, the heads are composed of the same material as the stalk. The heads preferably define a hollow base adapted to securely receive the connectors to facilitate the application of makeup. The heads may preferably be removed by a user when desired and replaced with an alternate brush and/or sponge head. The applicator may optimize space in a user's makeup case, save costs, and/or be travel friendly. The present applicator is preferably for use with cosmetic application, where different brush heads may be required to apply different forms of makeup (e.g., liquid, cream, powder, etc.)

A hair cleaning implement in the form of a laminate with surface properties specifically tailored to improve sebum removal from hair. The implement includes a nonwoven material joined to a film to form a laminate and a plurality of discrete protrusions extending from the surface of the nonwoven material. The protrusions are configured to provide the desired surface properties to the implement.

A cleaning tool for a laundry drying machine includes: a pad member having a first surface and a second surface; a cleaning member attached to the first surface of the pad member; one pair of bolt members vertically coupled to the second surface of the pad member; and one pair of nut members coupled to one pair of bolt members.

A flexible cleaning device which may include a handle assembly and a cleaning head connected thereto. The handle assembly may include a reservoir which may be in fluidic communication with the cleaning head that consists of a non-porous material. Within the cleaning head a emulsion cavity may be disposed that is in fluidic communication with both the reservoir and an area exterior to the cleaning head. And a method for using such a flexible cleaning device to remove dirt and debris from unclean surfaces.

A scrub brush having a main body with a top surface, a bottom surface, end walls, and side walls. A sponge is removably attached to a top surface of the main body. A plurality of bristles are attached to and extend away from the bottom surface of the main body. Either channels extend from the top surface of the main body to the bottom surface, or the main body has a hollow chamber.