A peristaltic pump may include a rotor rotatably mounted between a base of the peristaltic pump head and an end cap of the peristaltic pump head. The peristaltic pump may include an arcuate case between the base and the end cap partially surrounding the rotor. The peristaltic pump may include an arcuate occlusion bed removably mounted between the base and the end cap. The arcuate case and the arcuate occlusion bed form a cylindrical body around the rotor. The peristaltic pump may include a locking handle hingedly mounted to the arcuate occlusion bed, wherein the locking handle includes a bar extending between a pair of cam members, each cam member including a cam slot that engages a respective pin extending from the base and the end cap.

Hemodialysis and similar dialysis systems including a variety of systems and methods that make hemodialysis more efficient, easier, and/or more affordable, and include new fluid circuits for fluid flow in hemodialysis systems and a reciprocating diaphragm pump for pumping fluids. The reciprocating diaphragm pump includes a flexible diaphragm, a first rigid body having a curved pumping chamber wall, a second rigid body having an opposing curved control chamber wall. The diaphragm is interposed between the pumping chamber wall and the control chamber wall to define a pumping chamber and a control chamber. The diaphragm of the pump has a peripheral bead arranged to locate the diaphragm between the first rigid body and the second rigid body and a diaphragm body having a curved, semi-spheroid or domed shape. The diaphragm is pre-formed or molded so that during a delivery stroke of the pump, the elastic force of the diaphragm resisting its deployment into the pumping chamber prevents a peripheral portion of the diaphragm body from fully contacting the pumping chamber wall.

Hemodialysis and similar dialysis systems including a variety of systems and methods that make hemodialysis more efficient, easier, and/or more affordable, and include new fluid circuits for fluid flow in hemodialysis systems and a reciprocating diaphragm pump for pumping fluids. The reciprocating diaphragm pump includes a flexible diaphragm, a first rigid body having a curved pumping chamber wall, a second rigid body having an opposing curved control chamber wall. The diaphragm is interposed between the pumping chamber wall and the control chamber wall to define a pumping chamber and a control chamber. The diaphragm of the pump has a peripheral bead arranged to locate the diaphragm between the first rigid body and the second rigid body and a diaphragm body having a curved, semi-spheroid or domed shape. The diaphragm is pre-formed or molded so that during a delivery stroke of the pump, the elastic force of the diaphragm resisting its deployment into the pumping chamber prevents a peripheral portion of the diaphragm body from fully contacting the pumping chamber wall.

Described are fluid pumping and fluid handling systems, which may be suitable for use in medical devices, such as artificial or extracorporeal blood pumping systems. The systems can include a dual housing configuration for pneumatic actuation comprising a main housing containing a pump cassette comprising a pneumatically actuated pump and pneumatically actuated valves. The pump can include a pump actuation chamber and pump pneumatic port, and the valves can each include a valve actuation chamber and valve pneumatic port. Connecting tubes can be used to fluidly connect the pump actuation ports and valve actuation ports to a tube-support housing having a first side receiving one end of each connecting tube and a second side providing a pneumatic interface arranged to connect to an array of pneumatic receptacles on a base unit of the system to facilitate easy, compact and accurate pneumatic interconnection between the pump cassette and the base unit.

Described are fluid pumping and fluid handling systems, which may be suitable for use in medical devices, such as artificial or extracorporeal blood pumping systems. The systems can include a dual housing configuration for pneumatic actuation comprising a main housing containing a pump cassette comprising a pneumatically actuated pump and pneumatically actuated valves. The pump can include a pump actuation chamber and pump pneumatic port, and the valves can each include a valve actuation chamber and valve pneumatic port. Connecting tubes can be used to fluidly connect the pump actuation ports and valve actuation ports to a tube-support housing having a first side receiving one end of each connecting tube and a second side providing a pneumatic interface arranged to connect to an array of pneumatic receptacles on a base unit of the system to facilitate easy, compact and accurate pneumatic interconnection between the pump cassette and the base unit.

A negative pressure wound therapy device includes at least one piezoelectric pump and a control circuit. The control circuit is configured to generate a first control signal to control operation of the at least one piezoelectric pump, the control signal having a first root mean square (RMS) voltage, transmit the first control signal to the at least one piezoelectric pump, identify at least one of a change of state of the at least one piezoelectric pump or an expiration of a duration of time associated with operation of the at least one piezoelectric pump, responsive to identifying the at least one of the change of state or the expiration of the duration of time, generate a second control signal having a second RMS voltage less than the first RMS voltage, and transmit the second control signal to the at least one piezoelectric pump.

An apparatus for negative-pressure treatment may include an enclosure having a variable volume, a port and an actuation surface, a first one-way valve configured to allow fluid ingress to the enclosure, a second one-way valve configured to allow fluid egress from the enclosure, and an actuator configured to apply a linear force to the actuation surface.

A diaphragm for use in a pump includes a cover configured to contact fluid to pump the fluid and a backing disposed at least partially within the cover. The backing includes a flexible plate that extends outward relative to a core of the backing, the flexible plate configured to flex during reciprocation of the diaphragm. The cover is formed from a first polymer and the flexible plate is formed from a second polymer.

A pump head of a diaphragm booster pump, a diaphragm booster pump, a water treatment device and a method of operating a pump head. The pump head includes: a piston chamber, including a booster chamber arranged on an inner wall of the piston chamber; and a diaphragm, the booster chamber formed through enclosing the diaphragm, and the booster chamber radially expanding or compressing. The movement of two eccentric wheels with a phase difference of 180° in an eccentric assembly drives balance wheels of a balance wheel assembly to move oppositely. During rotation of the eccentric assembly, eccentric forces counteract each other, and the moment keeps balanced. The balance wheel assembly includes big small balance wheels, which are a first small balance wheel, the big balance wheel and a second small balance wheel in sequence, and the eccentric assembly drives the balance wheel assembly to swing eccentrically through a bearing.

A multi-chamber wobble plate pump having a housing with an inlet port, an outlet port and a plurality of pump chambers. A wobble plate is coupled to a diaphragm and a plurality of pistons. Rotation of the wobble plate moves the pistons within the pump chambers to draw in and force fluid out of the chambers. The pump includes a plurality of inlet valves each located within one of the pump chambers to control fluid flow from the inlet port to the pump chambers. Each inlet valve has an asymmetric cross-section, a thin section and a stem along a longitudinal axis. The thin section of the valve has less mechanical strength than the remaining portion of the valve. The valve is configured to open first at the thin section from reduced pressure during outward movement of the piston allowing air to be removed from the chambers.