Magnetic fluidic valves of the present disclosure may include a valve body having at least one cavity therein, a ferromagnetic gate transmission element disposed within the cavity, an inlet port, an outlet port, a permanent magnet configured to bias the gate transmission element to a closed position, and an electromagnetic coil configured to, upon actuation, overcome a magnetic force acting on the gate transmission element from the permanent magnet. The gate transmission element may be configured to move from the closed position blocking the inlet port to an open position unblocking the inlet port upon actuation of the electromagnetic coil. Various other fluidic systems and methods are also disclosed.

Adjustable fluidic oscillators are disclosed. A disclosed example oscillator includes a base having a cavity with a cross-sectional profile defining an oscillatory chamber between an inlet and an outlet of the oscillator, and a plunger to be received by the cavity and movable along a depth of the cavity to vary an aspect ratio of the oscillator.

Adjustable fluidic oscillators are disclosed. A disclosed example oscillator includes a base having a cavity with a cross-sectional profile defining an oscillatory chamber between an inlet and an outlet of the oscillator, and a plunger to be received by the cavity and movable along a depth of the cavity to vary an aspect ratio of the oscillator.

Systems, methods and devices are provided for the automated centrifugal processing of samples. In some embodiments, an integrated fluidic processing cartridge is provided, in which a centrifugation chamber is fluidically interfaced, through a lateral surface thereof, with a microfluidic device, and wherein the integrated fluidic processing cartridge is configured to be inserted into a centrifuge for centrifugation. A cartridge interfacing assembly may be employed to interface with the integrated fluidic processing cartridge for performing various fluidic processing steps, such as controlling the flow of fluids into and out of the centrifugation chamber, and controlling the flow of fluids into the microfluidic device, and optionally for the further fluidic processing of fluids extracted to the microfluidic device. The integrated fluidic processing cartridge may include a supernatant chamber the extraction of a supernatant thereto, and a diluent chamber for diluting a suspension collected in the centrifugation chamber.

Disclosed are techniques such as roll to roll processing to produce membrane valves in microelectromechanical systems that are integrated with micro-pumps that include a pump body having compartmentalized pump chambers. One application of this technology is as a valve assembly for a gas concentrator that includes a first micro pump for feeding an input gas stream, a second micro pump to supplying a vacuum and at least one sieve bed having a zeolite. The gas concentrator uses the valve assembly for controlling entry of gas from the first micro pump into the sieve bed and the second micro pump to vent.

A microvalve comprising a hard base 14, a clamping plate 12, an inlet port 96, 98, an outlet port 96, 98, a membrane 16, a ball bearing 18 and a drive head 20; wherein the hard base comprises a recess over which the membrane is clamped by the clamping plate, the recess defining a cup with a generally spherical cap shaped surface and a perimeter, both of the inlet and outlet ports being in the recess, and at least one of them being in the generally spherical cap shaped surface; wherein the membrane extends across the recess and is clamped thereover, and it is flexible for enabling the unclamped part of it to be flexed into the recess by the ball bearing in the clamping plate on the other side of the membrane to the recess upon actuation by the drive head behind the ball bearing for selective driving of the ball bearing against the membrane to flex the membrane into the recess as the membrane flexes around part of the ball bearing to move the membrane from a condition in which both ports are open to a port closing condition, the port closing condition being where the membrane has been flexed to extend over either one of, or alternatively both of, the input port and the output port, and clamped thereagainst by the ball bearing.

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

A microfluidic valve, includes arranging a substrate of a mechanically inert material to one or more physicochemical properties over time, configuring a structural portion of the valve; additive layer manufacturing to print, a succession of one or more filaments of a material with mechanical response to one or more of said physicochemical properties over time, preferably LCP, configuring a functional portion of the valve; and arranging the succession of filaments on the substrate, configuring a fluid flow rate through the valve using the application of an anti-adhesion treatment on one or more interfaces of said filaments and the substrate.

A three-way (3-way) Micro-Electro-Mechanical Systems (MEMS)-based micro-valve device and method of fabrication for the implementation of a three-way MEMS-based micro-valve which uses a single piezoelectric actuator. The present invention has a wide range of applications including medical, industrial control, aerospace, automotive, consumer electronics and products, as well as any application(s) requiring the use of three-way micro-valves for the control of fluids. The present invention allows for the implementation of a three-way microvalve device and method of fabrication that can be tailored to the requirements of a wide range of applications and fluid types. The microvalve may employ a novel pressure-balancing scheme wherein the fluid pressure balances the actuator mechanism so that only a small amount of actuation pressure (or force) is needed to switch the state of the actuator and device from open to closed, or closed to open.

The present invention generally relates to systems and methods for the control of fluids and, in some cases, to systems and methods for flowing a fluid into and/or out of other fluids. As examples, fluid may be injected into a droplet contained within a fluidic channel, or a fluid may be injected into a fluidic channel to create a droplet. In some embodiments, electrodes may be used to apply an electric field to one or more fluidic channels, e.g., proximate an intersection of at least two fluidic channels. For instance, a first fluid may be urged into and/or out of a second fluid, facilitated by the electric field. The electric field, in some cases, may disrupt an interface between a first fluid and at least one other fluid. Properties such as the volume, flow rate, etc. of a first fluid being urged into and/or out of a second fluid can be controlled by controlling various properties of the fluid and/or a fluidic droplet, for example curvature of the fluidic droplet, and/or controlling the applied electric field.