A thermal module for pre-heating liquid flowing into a liquid chromatography column, includes a trough compartment with two ends, one of the two ends having an electrical socket, a first fluidic assembly, a second fluidic assembly, and a clamp assembly. The clamp assembly includes a rail configured to receive the first fluidic assembly. The clamp assembly includes a carriage slidably mounted to the rail and configured to receive the second fluidic assembly. The carriage is operable to establish a first fluid tight seal between the first fluidic assembly and a chromatography column received within the clamp assembly, and to establish a second fluid tight seal between the second fluidic assembly and the chromatography column. The clamp assembly is disposed within the trough compartment, and the first fluidic assembly is plugged into the electrical socket at the one end of the trough compartment.

A tube fitting including a sleeve member having a circumferential collar portion, the circumferential collar portion including a first tapered surface, a first coupling member having a circumferential engagement flange portion configured to couple with the circumferential collar portion of the sleeve member, and a second coupling member that includes a longitudinally extended sealing portion. The longitudinally extended sealing portion includes a second tapered surface that couples with the first tapered surface so as to circumferentially expand the longitudinally extended sealing portion, when the first tapered surface and the second tapered surface are coupled to each other, and form a fluid seal between the second coupling member and the sleeve member.

A tool and methods of use is described. The tool tightens or loosens a fit of torque-limited fittings to respective ports of a fluid-handling device. The tool includes a torque application assembly disposed within a fitting receiving end of a tool body to receive a fitting. The tool body includes a slit between ends to receive a fitting tube. The torque application assembly includes an internal feature and a notch to align with the slit and receive the tube. In both a compressive direction of rotation under a threshold torque and an opposite, decompressive direction of rotation, the internal feature is configured for engagement with a resilient feature of the fitting such that rotation of the torque application assembly causes a fitting rotation. In a compressive direction of rotation at or above the threshold torque, rotation of the torque application assembly fails to cause a fitting rotation.

A tool and methods of use is described. The tool tightens or loosens a fit of torque-limited fittings to respective ports of a fluid-handling device. The tool includes a torque application assembly disposed within a fitting receiving end of a tool body to receive a fitting. The tool body includes a slit between ends to receive a fitting tube. The torque application assembly includes an internal feature and a notch to align with the slit and receive the tube. In both a compressive direction of rotation under a threshold torque and an opposite, decompressive direction of rotation, the internal feature is configured for engagement with a resilient feature of the fitting such that rotation of the torque application assembly causes a fitting rotation. In a compressive direction of rotation at or above the threshold torque, rotation of the torque application assembly fails to cause a fitting rotation.

The present disclosure relates to purification cassettes that have reinforcing features. One embodiment relates to a purification cassette with tensions members. A purification system may include a removable cassette defining a media cavity. A set of tension members may span between a first sidewall and second sidewall. The set of tension members can divide the media cavity into a plurality of lanes.

A screwed end connector assembly includes a threaded connector having a conical end portion for the reception of a mating hose fitting. The connector has a flange which includes at least one arcuate, circumferentially extending slot. A nut for threaded engagement with the connector, for securing a hose end fitting to the conical portion of the connector, has a polygonal exterior. A member has an aperture for fitment over and irrotational engagement with the exterior of the nut and includes at least one hole positionable in axial register with the said slot.

An adapter for selectively providing fluid to a device from one of multiple fluid sources has a body with a first inlet for connecting a first one of the multiple fluid sources to the device and a second inlet for connecting a second one of the multiple fluid sources to the device. The adapter also includes a handle that is movably coupled to the body and includes an access control element. The handle is configured to secure the body to a device when the adapter is in either of a first position or a second position that is rotated relative to the first configuration. The access control element obstructs access to the second inlet when the adapter is secured to the device in the first position and the access control element obstructs access to the first inlet when the adapter is secured to the device in the second position.

A housing component includes a line segment of a hydraulic line. The line segment has at least one channel that opens into a widening. The widening extends to outside of the housing component. A spatially limited sealing surface enclosing the channel is provided in the widening. A seal comprising an adhesive is joined to the sealing surface at least adhesively. A method for manufacturing such a housing component includes layered manufacture of the sealing surfaces.

A housing component includes a line segment of a hydraulic line. The line segment has at least one channel that opens into a widening. The widening extends to outside of the housing component. A spatially limited sealing surface enclosing the channel is provided in the widening. A seal comprising an adhesive is joined to the sealing surface at least adhesively. A method for manufacturing such a housing component includes layered manufacture of the sealing surfaces.

A swage visual indicator for a fluid coupling is disclosed and related methods. The swage visual indicator is achieved by a non-destructive visual indication of a swaging process by one or more swage apertures formed through a flange filled with an indicator material. The swage apertures communicate with swaging grooves of the fluid conveying components being joined. As the swaging process is conducted, the swaging grooves are filled with material from one of the fluid conveying components, and the indicator material within the aperture(s) is therefore displaced in a direction toward the exposed exterior surface of the flange. According to a successful swaging process, the indicator material is displaced to a degree such that the indicator material is visible by the unaided eye of an inspector.