G01N15/00

Microorganism evaluation system
11454585 · 2022-09-27 · ·

A microorganism evaluation system comprising a viewing section for image acquisition, the viewing section comprising a viewing port configured to accommodate a fluid flow, at least one independently controlled imaging light source operably installed in the viewing section and configured to selectively illuminate the viewing port, and at least one independently controlled light stimulation device operably installed in the viewing section and configured to selectively emit light for invoking a motile response in a microorganism within the fluid flow in the viewing port, whereby the system synchronizes illumination of the at least one imaging light source and the at least one light stimulation device of the viewing section.

Cell capture system and method of use
11237096 · 2022-02-01 · ·

A cell capture system including an array, an inlet manifold, and an outlet manifold. The array includes a plurality of parallel pores, each pore including a chamber and a pore channel, an inlet channel fluidly connected to the chambers of the pores; an outlet channel fluidly connected to the pore channels of the pores. The inlet manifold is fluidly connected to the inlet channel, and the outlet channel is fluidly connected to the outlet channel. A cell removal tool is also disclosed, wherein the cell removal tool is configured to remove a captured cell from a pore chamber.

Field-array free flow fractionation

An example includes a field-flow fractionation device for the continuous separation of sample components including a channel comprising a sample inlet and a plurality of sample outlets, the channel being for coupling to a flow generator for translocating the sample components along the channel in a first direction from the sample inlet to the plurality of sample outlets, an actuator, which is not the flow generator, coupled to the channel, for translocating the sample components in a second direction, at a first angle with the first direction, an array of electrodes for connection to an AC power source, being in a path taken by the sample components in the channel, arranged in a plurality of rows, and in such a way that adjacent rows can be set at different potentials and every other row can be set at the same potential.

Evaluation of focusing performance in an assay analysis system
09719855 · 2017-08-01 · ·

Methods, storage mediums and systems (MS&S) are provided which successively image an imaging region of an assay analysis system (AAS) as particles are loaded into the imaging region, generate a frequency spectrum of each image via a discrete Fourier transform, integrate a same coordinate portion of each frequency spectrum and terminate the loading of particles upon computing an integral which meets preset criterion. In addition, MS&S are provided which send a signal indicative of whether enough particles are in an imaging region for further processes by an AAS based on the magnitude of integral calculated from an image's frequency spectrum. MM&S are also provided such that the steps of generating a frequency spectrum of each image and integrating a portion of each frequency spectrum are replaced by generating a convolved spatial image with a filter kernel and integrating a same coordinate portion of each convolved spatial image.

Particulate detection system

A particulate detection system (1) for detecting the quantity of particulates S in a gas under measurement EG, including a detection section (10), a drive circuit (210, 240), and a control section (230, 202). The detection section (10) has an ion source (11) and a particulate electrification section (12). The drive circuit (210) includes an ion source drive circuit (210) for performing constant current control. The control section (230, 202) includes current convergence determination means S2-S3, S5-S6, and detection start means S8 for starting detection of the quantity of the particulates S using the signal Is, detected by a detection circuit (230), after the gaseous discharge current Id has converged to an allowable range IR.

Cell observation device, and cell observation method

A cell observation system 1, for measuring fluorescence emitted from a cell held by a microplate 20 having a plurality of wells 21, comprises a microplate holder 11 for mounting the microplate 20, an electrical stimulator 16 arranged with a plurality of electrode pairs 17 including positive and negative electrodes 17b, 17a, a position controller 30 for controlling a position of the electrical stimulator 16 so as to place the electrode pairs 17 within the wells 21, a moving image acquisition unit 40 for detecting the fluorescence from the sample S within the wells 21, and a data analyzer 50 for setting a part of a region facing the positive electrode 17b on the well 21 as an analysis region and analyzing an optical intensity in the analysis region so as to acquire analysis information concerning the sample S.

LIQUID-SAMPLE COMPONENT ANALYSIS METHOD
20170269071 · 2017-09-21 · ·

A liquid-sample component analysis method includes a dripping step of dripping a liquid sample onto a flat horizontal surface, a drying step of drying a liquid droplet of the liquid sample formed on the horizontal surface while keeping the liquid droplet still so as to obtain a plurality of concentrically-arranged ring-shaped deposits formed on the horizontal surface and composed of components having different particle diameters, and a measuring step of measuring a vibrational spectrum in each region including only one of the deposits so as to individually acquire vibrational spectra of the plurality of deposits.

Recycle Diluent For Wellbore Fluid Sampling System

A wellbore fluid sampling system and method of operation are provided. A wellbore fluid sampling system may comprise a mixing system coupled to a wellbore sample supply and a recycled diluent supply, a fluid analysis system coupled to the mixing system, and a diluent recycle system coupled to the fluid analysis system and the mixing system, wherein the diluent recycle system comprises an evaporator and a condenser. A method for recycling diluent may comprise combining a wellbore fluid sample with a diluent to form a diluted wellbore fluid sample, analyzing the diluted wellbore fluid sample to determine one or more fluid properties, separating at least a portion of the diluent from the wellbore fluid sample in the diluted wellbore fluid sample, and recycling the separated portion of the diluent for re-use.

Basophil analysis system and method

Provided herein are systems and methods for analyzing blood samples, and more specifically for performing a basophil analysis. In one embodiment, the systems and methods include: (a) staining a blood sample with an exclusive cell membrane permeable fluorescent dye; and then (b) using measurements of light scatter and fluorescence emission to distinguish basophils from other WBC sub-populations. In one embodiment, the systems and methods include performing a basophil cluster analysis of the blood sample, based on the combination of light scatter and fluorescence measurements.

ANALYSIS METHOD, ANALYSIS DEVICE, AND PROGRAM
20220228962 · 2022-07-21 ·

An analysis method of analyzing a behavior of a particle system that includes a plurality of particles forming a flow field by using a renormalized molecular dynamics method, includes: performing renormalization on the particle system according to a degree of renormalization determined for each of three orthogonal directions according to a shape of the flow field; and numerically solving a motion equation governing a motion of the particle system with respect to the particle system after the renormalization, in which in the performing of renormalization, the number of particles is reduced according to the degree of renormalization, and the mass of each particle is increased according to the degree of renormalization without changing the shape and volume of the flow field before and after the renormalization, and an interaction potential between the particles is transformed according to the degree of renormalization in each of the three directions.