In accordance with certain embodiments, detection of a fire event via detection of scattered light of at least two wavelengths is initiated only after a signal from a light detector and/or a sensor for detecting one or more fire signatures other than smoke exceeds a triggering threshold.

A portable in-vitro (PIV) diagnostic detector operable to perform a fluorescence assay on a sample in one or more detection chambers of a cartridge is provided. The PIV diagnostic detector comprises a first optical module which includes (i) an LED light source for emitting substantially monochromatic light to illuminate a detection zone associated with at least one detection chamber; (ii) an excitation filter interposed between said light source and said detection zone; (iii) a light detector operable to detect fluorescent light emitted by an excited fluorescent label associated with the sample and to measure an intensity of the fluoresced light; and (iv) an emission filter interposed between said light detector and said detection zone. The (PIV) diagnostic detector further comprises a microprocessor operable to process the measured intensity of the fluoresced light to determine whether an analyte is present in the sample; wherein the first optical module is configured such that a longitudinal axis of the light source extends at an oblique angle with respect to a longitudinal axis of the light detector.

Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member.

This disclosure describes various system and methods for monitoring photons emitted by a heat source of an additive manufacturing device. Sensor data recorded while monitoring the photons can be used to predict metallurgical, mechanical and geometrical properties of a part produced during an additive manufacturing operation. In some embodiments, a test pattern can be used to calibrate an additive manufacturing device.

This disclosure describes various system and methods for monitoring photons emitted by a heat source of an additive manufacturing device. Sensor data recorded while monitoring the photons can be used to predict metallurgical, mechanical and geometrical properties of a part produced during an additive manufacturing operation. In some embodiments, a test pattern can be used to calibrate an additive manufacturing device.

The disclosure provides for structured illumination microscopy (SIM) imaging systems. In one set of implementations, a SIM imaging system may be implemented as a multi-arm SIM imaging system, whereby each arm of the system includes a light emitter and a beam splitter (e.g., a transmissive diffraction grating) having a specific, fixed orientation with respect to the system's optical axis. In a second set of implementations, a SIM imaging system may be implemented as a multiple beam splitter slide SIM imaging system, where one linear motion stage is mounted with multiple beam splitters having a corresponding, fixed orientation with respect to the system's optical axis. In a third set of implementations, a SIM imaging system may be implemented as a pattern angle spatial selection SIM imaging system, whereby a fixed two-dimensional diffraction grating is used in combination with a spatial filter wheel to project one-dimensional fringe patterns on a sample.

The present invention relates to enhancement of detectable emissions from carbon nanodots or variants thereof by using the techniques of MEF to further enhance carbon nanodot brightness, photostability, and thus, potentially detectability in biological imaging applications by using plasmon supporting materials, such as silver island films and positioning of the carbon nanodots an optimal distance from the plasmon supporting materials.

A spectrophotometer includes: a sample-chamber lid capable of opening and closing an opening portion of a sample chamber for setting a sample and a reference sample; and sample-chamber lid opening-closing detecting means for detecting an opening-closing state of the sample-chamber lid, and the spectrophotometer is capable of controlling a measurement of a xenon flash tube as a light source, a spectroscope, a detector, an amplifier, an AD converter, a processor, a storage device, and a data display part. In the spectrophotometer, the light source is turned on after a state of the lid changing from an opening state to a closing state is detected in a sample-setting instruction state by the sample-chamber lid opening-closing detecting means; absorbancy, transmissivity, reflectivity, a sample-side energy value, or a reference-side energy value is measured; and a measurement result is displayed on the data display part.

Distributions of a Brillouin frequency shift and a Rayleigh frequency shift in optical fibers set up in a material are measured from scattered waves of pulse laser light entered into the optical fibers, and distributions of pressure, temperature, and strain of the material along the optical fibers at a measurement time point are analyzed using coefficients that are inherent to the set up optical fibers and correlate pressure, temperature, and strain of material with the Brillouin frequency shift and the Rayleigh frequency shift.

A cytometer includes an avalanche photodiode, a switching power supply, a filter, and voltage adjustment circuitry. The switching power supply includes a feedback loop. The filter is electrically connected between the switching power supply and the avalanche photodiode. The voltage adjustment circuitry adjusts a voltage on the feedback loop based at least in part on a voltage measured between the filter and the avalanche photodiode.