A cytometer includes an avalanche photodiode, a switching power supply, a filter, and voltage adjustment circuitry. The switching power supply includes a feedback loop. The filter is electrically connected between the switching power supply and the avalanche photodiode. The voltage adjustment circuitry adjusts a voltage on the feedback loop based at least in part on a voltage measured between the filter and the avalanche photodiode.

A transmission spectroscopy device can direct light into a sample, and determine properties of the sample based on how much light emerges from the sample. The device can use a cell to contain the sample, so that the size of the cell defines the optical path length traversed by light in the sample. To ensure accuracy in the measurements, it is beneficial to calibrate the device by measuring the size of the cell periodically or as needed. To measure the size of the cell, the device can perform a transmission spectroscopy measurement of a known substance, such as pure water, to produce a measured absorbance spectrum of the known substance. The device can subtract a known absorbance spectrum of the known substance from the measured absorbance spectrum to form an oscillatory fringe pattern. The device can determine the size of the cell from a period of the fringe pattern.

An instrument is provided that can monitor nucleic acid sequence amplification reactions, for example, PCR amplification of DNA and DNA fragments. The instrument includes a multi-notch filter disposed along one or both of an excitation beam path and an emission beam path. Methods are also provided for monitoring nucleic acid sequence amplifications using an instrument that includes a multi-notch filter disposed along a beam path.

The present invention relates to an inspection device and particularly to a device using an array of light sources and photo-detection devices to evaluate threaded workpieces for conformance to spatial form criteria. The invention provides for improved identification of flaws in threaded components to identify the conformance of parts.

The present invention relates to the use of a substrate for enhancing the fluorescence of a fluorescent molecule, wherein the substrate comprises a solid polymer carrier having a plurality of recesses separated from each other and wherein the solid carrier is coated at least in part by a metal.

The disclosed techniques include obtaining a first signal generated by an electrochemical glucose sensor and a second signal generated by an optical glucose sensor, and obtaining a glucose value indicative of a user's blood glucose level, where the glucose value and the second signal are obtained at different times. The disclosed techniques further cause calculating a mapped value for the second signal based on the first signal, and calibrating the mapped value of the second signal based on the glucose value.

The disclosed techniques include obtaining a first signal generated by an electrochemical glucose sensor and a second signal generated by an optical glucose sensor, and obtaining a glucose value indicative of a user's blood glucose level, where the glucose value and the second signal are obtained at different times. The disclosed techniques further cause calculating a mapped value for the second signal based on the first signal, and calibrating the mapped value of the second signal based on the glucose value.

Methods of detecting a non-explosive analyte can include exposing a sensor compound to a non-explosive analyte and displaying a change in the sensor compound upon exposure of the sensor compound to the non-explosive analyte. A variety of sensor compounds for detecting a target analyte, including both explosive and non-explosive analytes, is also described. Sensor devices for detecting a target analyte can include a substrate and a sensor compound positioned on the substrate in a plurality of detection zones.

A photo-thermal speckle spectroscopy device having an infrared laser, a visible laser, a foam, and a camera. The infrared and visible lasers are focused on the foam, which causes the visible laser to scatter. A camera records the speckle pattern, which shifts when the IR laser is turned on. The related method of photo-thermal speckle spectroscopy is also disclosed.

Disclosed is a connecting device for connecting a gas sensor to a gas leak detector. The gas sensor includes an elongate sensor housing. The gas leak detector includes at least one gas connector adapted to be connected to the gas sensor. A guide rail connects to the gas leak detector, engaging with the sensor housing such that the gas connectors engage with at least one complementary second gas connector. A fastening claw includes two elastic spring legs arranged at one of the sensor housing and the gas leak detector. Each of the two spring legs includes a latching boss engaging the frontal end of the gas sensor opposite the second gas connector and a spreading element having two retaining arms. Each retaining arm includes a pulling edge, an inclined insertion portion along which the latching boss grips and pivots the spring leg, and an inclined disengagement portion.