The present invention relates to detection systems for detecting an opioid compound by use of pyrolysis, as well as methods thereof. In particular, the systems are configured to detect the presence of a backbone fragment indicative of a class of opioid compounds, including opioid analogues.

The present disclosure describes a method, a system, and a computer program product of performing a separation on a field flow fractionator. In an embodiment, the method, the system, and the computer program product include executing, by a computer system, a set of logical operations measuring a mass flow control valve position of a control valve connected to a mass flow controller coupled to a field flow fractionator and a pressure control valve position of a control valve connected to a pressure controller coupled to the field fold fractionator in an optimal stability state, storing, by the computer system, the valve positions to a data store as preset values, and executing, by the computer system, a set of logical operations retrieving the preset values from the data store and setting initial conditions for the controllers corresponding to the preset values, resulting in a switch mode of the field flow fractionator.

Enantiomers may be analyzed by: (1) reacting a mixture of a first compound and a second compound that are a pair of enantiomers with an axially chiral compound that is one of a pair of axially chiral isomers, to generate a derivative mixture containing a first derivative obtained by a reaction of the first compound with the axially chiral compound and a second derivative obtained by a reaction of the second compound with the axially chiral compound; (2) separating the first derivative and the second derivative in the derivative mixture; and (3) detecting the separated first derivative and second derivative by mass spectrometry.

Methods include treating a portion of a sample composition to be tested for presence of an analyte by depleting or blocking the target analyte. The treated composition may be used to equilibrate an acoustic wave sensor prior to exposing the sensor to the untreated sample composition for analysis. By using the treated sample composition, in which the analyte is depleted or blocked, to equilibrate the sensor, the sensor may be equilibrated with a composition having a similar viscosity and non-specific binding characteristics to the untreated sample composition, which should result in improved accuracy when analyzing the analyte in the untreated sample composition.

A method for separating diastereomers of pristane. A pristane sample is prepared, and then injected into a chromatographic instrument equipped with a chiral chromatographic column, where a stationary phase of the chiral chromatographic column has a preset pore size. The pristane diastereomers in the pristane sample are separated by the chiral chromatographic column, and the components produced by the separation of the pristane diastereomers sequentially enter a mass spectrometer for detection and analysis.

The present disclosure describes a field flow fractionator including (a) a top plate assembly including a top electrically conductive electrode, (b) an o-ring, (c) an electrically insulating frit, (d) an electrically insulating spacer between a bottom surface of the top electrode and the o-ring and the frit, (e) a membrane between the spacer and the frit, and (f) a bottom plate assembly including a bottom electrically conductive electrode.

An object of the disclosure is to determine the remaining saturation of existing fluids in naturally fractured and/or homogeneous reservoirs, considering an unconventional tracer test, using the double tracer test method with pressure monitoring (PDTcMP®), which also integrates unused technical elements, in order to estimate more accurately the value of the remaining oil saturation (ROS) in naturally fractured reservoirs, unlike conventional methods used most commonly in homogeneous media. The disclosure substantially modifies the conventional tracer test, as it uses innovative technical elements, which reduce the uncertainty and/or ambiguity associated with conventional tracer tests, when they are applied in naturally fractured reservoirs.

An object of the disclosure is to determine the remaining saturation of existing fluids in naturally fractured and/or homogeneous reservoirs, considering an unconventional tracer test, using the double tracer test method with pressure monitoring (PDTcMP®), which also integrates unused technical elements, in order to estimate more accurately the value of the remaining oil saturation (ROS) in naturally fractured reservoirs, unlike conventional methods used most commonly in homogeneous media. The disclosure substantially modifies the conventional tracer test, as it uses innovative technical elements, which reduce the uncertainty and/or ambiguity associated with conventional tracer tests, when they are applied in naturally fractured reservoirs.

The present disclosure describes a method, a system, and a computer program product of analyzing data collected by analytical instruments. In an embodiment, the method, the system, and the computer program product include receiving set-up information, running at least one incomplete analytical method on at least one known sample on at least one analytical instrument with respect to the set-up information, resulting in known sample data, processing the at least one incomplete analytical method with respect to the known sample data, resulting in at least one validated analytical method, and running the at least one validated analytical method on at least one unknown sample on the at least one analytical instrument with respect to the set-up information, resulting in analyzed sample data.

Disclosed are fibers which contain identification fibers. The identification fibers can comprise one or more chemical markers, or taggants, which may vary among the fibers or be incorporated throughout all of the fibers. The disclosure also relates to the method for making and characterizing the fibers. Characterization of the fibers can include identifying chemical markers and correlating the chemical markers and a taggant chemical marker amounts of at least one of the chemical markers to manufacturer-specific taggants to determine supply chain information. The supply chain information can be used to track the fibers from manufacturing through intermediaries, conversion to final product, and/or the consumer.