A device for the detection of a food allergen includes a sensor having a printed circuit board and a chip comprising a molecularly imprinted polymer (MIP) and a non-imprinted polymer (NIP); a reservoir comprising a liquid; and a chamber for mixing the liquid with a food.

Disclosed is a FRET based assay and related products. The assay employs molecular imprinted polymers having a very high affinity for their target.

In a first aspect, the present disclosure relates to a method for immobilizing a molecularly imprinted polymer onto a substrate, comprising providing a substrate having an amorphous carbon surface; and grafting the molecularly imprinted polymer onto the amorphous carbon surface.

A polymer-based sensor for detecting agricultural analytes is disclosed, including stable polymer-based sensing films such as molecular imprinted polymers (MIPs) that can be incorporated in sensors for detecting herbicides and pesticides, as well as methods of making the sensing films.

A device for the detection of a food allergen includes a sensor having a printed circuit board and a chip comprising a molecularly imprinted polymer (MIP) and a non-imprinted polymer (NIP); a reservoir comprising a liquid; and a chamber for mixing the liquid with a food.

A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a photonic structure integrated with a receptor, wherein the photonic structure may be configured such that, when an analyte contacts the receptor within the photonic structure, a refractive property of the photonic structure changes thereby to cause a detectable color change in the photonic structure. The photonic structure may comprise an optical absorber indicator, wherein the receptor may be associated with the optical absorber indicator, such that, when the analyte contacts the receptor, the analyte causes a color change of the optical absorber indicator via a photo-induced electron transfer mechanism. The optical absorber indicator may comprise the photo-induced electron transfer mechanism.

The present disclosure provides new approaches in developing templated polymer-based chemical receptors. At least some embodiments of the invention use a stimuli-responsive polymer [e.g., poly-Nisopropylacrylamide (pNIPAM)] as a polymer backbone with the incorporation of functional monomers (for analyte recognition). In at least some embodiments of the invention, vinylferrocene may be used as a redox-active label for electrochemical transduction.

A composition of matter has a molecularly imprinted polymer having templated pores, and a reactive material occupying a portion of each pore, the reactive material selected to react when an analyte material for which the cavities are templated enters the cavities. A method of synthesizing a molecularly imprinted polymer includes arranging monomers around a template molecule having a reactive component and an analyte component, polymerizing the monomers, removing the template molecule, and reintroducing the reactive component of the template molecule. A method of detecting an analyte includes exposing a molecularly imprinted polymer to a fluid, the polymer having templated pores containing a detector material that is reactive to an analyte.

Molecularly Imprinted Polymers (MIPs) are utilized to detect diseases and minimize false negative/positive scenarios. MIPs are implemented on a nano-electric circuit in a biochip where interactions of MIPs and an Antigen/Antibody (AG/AB) are detected, and disease specific biomarkers diagnosed. Biomarker detection is achieved with interdigitated gold electrodes in a biochip's microchannel. Capacitance changes due to biomarker interaction with AG/AB electrode coating diagnose diseases in a microfluidic environment. Biofluid passes through the microchannel and exposed to the nanocircuit to generate a capacitance difference and diagnose any specific disease in the biofluid sample. Blood capillary flow in a microchannel curved section experience centrifugal forces that separate liquid from solid. Various blood densities and segments experience different centrifugal effects while flowing through the curved section so serum is separated from various solid matter without using external devices.

A polymer-based sensor for detecting agricultural analytes is disclosed, including stable polymer-based sensing films such as molecular imprinted polymers (MIPs) that can be incorporated in sensors for detecting herbicides and pesticides, as well as methods of making the sensing films.