Among other things, sound records captured from a subject by auscultation at sound capture points on the subject are classified among sound classes. Respiratory conditions can be inferred from the sound records and other information. Information about the respiratory conditions can be presented to the subject or to a healthcare provider for purposes of managing the respiratory conditions.

Cough is a common experience and the most frequent reason why an individual seeks a visit to a physician. The prevalence of cough is about 10+% of the population. Cough is a manifestation of many aerodigestive tract disorders and especially consequential for serious lower airway diseases such as respiratory infections, chronic obstructive pulmonary disease (COPD) and asthma because increased coughing leads to emergency room visits and hospitalization. There is a need for methods to oversee coughing frequency in certain patients. Traditionally, all automated cough monitors have used cough sound as the signal for the measurement of cough. In the present invention movements of the diaphragm muscle, recorded by a motion sensor placed above the xiphoid process, are used for counting coughs. A device for such recordings is described and data were collected. This method is validated by using citric acid spray to trigger cough sounds and to show that the provoked acoustic signal is matched by the electronic signals from the movement sensors. The xiphoid process is a unique anatomical landmark for the non-acoustic detection of cough.

Embodiments disclosed herein improve digital stethoscopes and their application and operation. A first method detects of a respiratory abnormality using a convolution. A second method counts coughs for a patient. A third method predicts a respiratory event based on a detected trend. A fourth method forecasts characteristics of a future respiratory event. In a fifth embodiment, a base station is provided for a digital stethoscope.

Technologies are described to control and optimize a delivery timing and dosage of agents, such as nootropics, in an individually tailored manner. Nootropics enhance cognitive functions, including executive functions, memory, creativity and/or motivation. Typically, nootropic regimes require a person to orally take multiple different agents at different dosages and at different times of the day. Embodiments are directed to instructing a delivery device to deliver an agent at a predefined time and dosage to an individual, receiving an input associated with parameters related to a physiological function and/or a cognitive function of the individual, and processing the input to analyze an efficacy of the agent. The predefined time and/or dosage for delivery of the agent to the individual may then be adjusted based on the analysis. The delivery device may be a standalone device or may be integrated with various other items.

Technologies are described to control and optimize a delivery timing and dosage of agents, such as nootropics, in an individually tailored manner. Nootropics enhance cognitive functions, including executive functions, memory, creativity and/or motivation. Typically, nootropic regimes require a person to orally take multiple different agents at different dosages and at different times of the day. Embodiments are directed to instructing a delivery device to deliver an agent at a predefined time and dosage to an individual, receiving an input associated with parameters related to a physiological function and/or a cognitive function of the individual, and processing the input to analyze an efficacy of the agent. The predefined time and/or dosage for delivery of the agent to the individual may then be adjusted based on the analysis. The delivery device may be a standalone device or may be integrated with various other items.

An acoustic system can track gas emissions by exploiting the nostril-accessible nasal pathways of an animal. Actuators and microphones used in the apparatus can be similar to those currently found in cell phones, which in turn make the acoustic apparatus small and rugged. The nostril geometry can be mapped using sound waves, similar to the mapping done by an acoustic rhinometer. Where acoustic rhinometers assume a constant speed of sound to measure changes in geometry, acoustic approaches as disclosed herein can assume constant geometry to measure changes in the speed of sound. Approaches disclosed here are particularly useful with any gas, such as (for example) methane, hydrogen, helium, etc. that has a speed of sound higher than other typical gaseous components of exhaled air, such as nitrogen, carbon-dioxide, oxygen, etc.

A medical device (20) includes a case (32), having a front surface that is configured to be brought into contact with a body of the living subject (24). A microphone (34) is contained in the case and configured to sense acoustic waves emitted from the body and to output an acoustic signal in response thereto. A proximity sensor (56) is configured to output a proximity signal indicative of contact between the front surface and the body. At least one speaker (49) is configured to output audible sounds. Processing circuitry (50) is coupled to detect, in response to the proximity signal, that the front surface is in contact with the body, and in response to the detected contact, to process the acoustic signal so as to generate an audio output and to convey the audio output to the at least one speaker.

Disclosed is a multi-channel digital stethoscopy system. The present invention can provide accurate and detailed medical examination information by separating and filtering stethoscopy sounds received from a plurality of transmission units by frequency in a single reception terminal, dividing the filtered stethoscopy sounds into cardiac sounds and lung sounds, and then outputting the same.

An overdose of opioids can cause the user to stop breathing, resulting in death. A physiological monitoring system packaged as a kit includes a sensor assembly including a sensor that is configured to sense the at least one physiological parameter, a base station that includes a processor and memory storing instructions that when executed cause the processor to process data from the sensor to provide the at least one physiological parameter and to determine an opioid overdose event based on the at least one physiological parameter, a self-administrating medication applicator having an injector and a dose of an opioid receptor antagonist, and a tray having molded depressions to hold the base station, the sensor assembly, and the self-administrating medication applicator.

A method includes receiving sensor data associated with respiration of a user at a first electronic device. The method also includes extracting features specific to paradoxical vocal cord motion (PVCM) from the sensor data, the extracted features comprising a cough wetness level and a respiration phase difficulty level. The method also includes calculating a PVCM score based on the extracted features using a predetermined model, wherein the predetermined model allocates weights to the extracted features based on respective importance to PVCM determination. The method also includes presenting an indicator on a display of the first electronic device for use by the user or a medical provider, the indicator representing the PVCM score.