A device for sampling an initial volume of a liquid flow is disclosed which comprises an inlet conduit, an outlet conduit, and valve casing. The valve casing has a passageway formed therethrough. A sample outlet extends through the valve casing and into the passageway. A valve structure is arranged for axial movement in the valve casing. A gate of the valve structure obstructs the passageway and prevents an initial volume of the liquid flow from being transferred to the outlet conduit when the valve structure is moved to a sampling position. A stem of the valve structure obstructs the sample outlet without obstructing the passageway when the valve structure is moved to a diverting position. At least one elongated groove is formed in a surface of the gate and extends into the stem such that the initial volume is directed through the sample outlet and towards a receptacle when the valve structure is moved to the sampling position. A lifting member moves the valve structure from the sampling position to the diverting position.

Aspects of the methods include volumetrically imaging testicular tissue by optical coherence tomography to identify a testicular tissue location that is likely to contain sperm; and m-mode scanning using optical coherence tomography the identified testicular location to determine whether sperm are at least likely to be present at the location. Methods may further include harvesting sperm from the location, e.g., for use in in vitro fertilization. Also provided are devices and systems for practicing the methods.

Methods and kits for collecting and verifying a specimen and/or biological information from a person at a first location to be provided to a second location are provided with documentation of chain of custody in order to verify that the person from whom the specimens and data were obtained is the intended person. Methods include internet and/or video communication between the person and a human or software-based verification assistant, confirming identification of the person to the verification assistant through the video communication, obtaining one or more specimens from the person or one or more types of biological information of the person, wherein the obtaining may be recorded through the internet/video communication, and the use and recording of coded tamper-evident packaging to ensure chain of custody before, during and after the internet/video communication.

Multi-layer contact patches, as well as related apparatus, kits, systems, and methods, enable improved allergen testing and diagnosis. Multi-layer contact patches include a shield layer releasably coupled to an adhesive layer. The adhesive layer at least partially defines and is fixably coupled to an allergen complex layer. The allergen complex layer defines a plurality of allergen complex cavities. At least a subset of the allergen complex cavities include an allergen complex positioned therein, each allergen complex comprising an absorbent matrix and an allergen.

Multi-layer contact patches, as well as related apparatus, kits, systems, and methods, enable improved allergen testing and diagnosis. Multi-layer contact patches include a shield layer releasably coupled to an adhesive layer. The adhesive layer at least partially defines and is fixably coupled to an allergen complex layer. The allergen complex layer defines a plurality of allergen complex cavities. At least a subset of the allergen complex cavities include an allergen complex positioned therein, each allergen complex comprising an absorbent matrix and an allergen.

An example angled sampling swab includes: a swab head comprising an absorbent material for specimen sample collection; and a handle. The handle includes: a first handle portion, wherein the swab head is attached to the second handle portion; and a second handle portion comprising a notch enabling separation of part of the second handle portion to enable insertion of the swab head and the first handle portion into a transport vial, the second handle portion arranged at an angle of 80 degrees or greater and less than 170 degrees with respect to the first handle portion, such that the swab head is arranged at the same angle with respect to the first handle portion

An oral assembly (100) for use within a mouth of a user. The oral assembly (100) includes an oral device (104) and a collection device (224). The oral device (104) is configured to be usable within the mouth of the user to provide oral health care treatment. The collection device (224) is coupled to the oral device (104). The collection device (224) is movable between (i) a collection mode wherein the collection device (224) collects saliva from the mouth of the user, and (ii) an expulsion mode wherein the collection device (224) expels a liquid into the mouth of the user. A collection tube (226) can be coupled to the collection device (224). The collection tube (226) can be configured to receive saliva that is collected by the collection device (224) from the mouth of the user.

A sanitary device for the urine glucose test includes a urine container formed on an inner wall of a main body, and a measuring module with an inner space mounted at a bottom of the urine container. Within the inner space, a lens attaches to the bottom of the urine container, a rail faces a bottom surface of the lens, and a driving module moves a light unit shooting a detection beam to a measuring surface of the lens along the rail. The measuring surface contacts urine in the urine container, and reflects the detection beam out of the bottom surface into a sensor. The sensor is electrically connected to a processor. The processor determines a urine glucose level and generates a urine glucose level data instantly from an angle of incidence of the detection beam on the measuring surface and from a beam intensity signal from the sensor.

A syringe-based device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive and isolate a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.

An apparatus includes a transfer adapter, a puncture member, a disinfection member, and a fluid reservoir. The transfer adapter has a proximal end portion and a distal end portion, and defines an inner volume configured to receive the puncture member. The transfer adapter is coupled to the disinfection member. The distal end portion of the transfer adapter includes a port fluidically coupled to the puncture member and configured to be placed in fluid communication with a bodily-fluid of a patient. The proximal end portion is configured to receive a portion of the fluid reservoir to allow the fluid reservoir to be moved within the inner volume between a first position, in which a surface of the fluid reservoir is placed in contact with the disinfection member, and a second position, in which the puncture member punctures the surface to place the puncture member in fluid communication with the fluid reservoir.