A microsurgical instrument having one or more distance indication members is provided. In a particular embodiment, the microsurgical instrument comprises a microsurgical tool and a first distance indication member coupled to, and extending beyond a distal end of, the microsurgical tool. A distal portion of the first distance indication member may be configured to deflect when in contact with a tissue surface, without causing damage to the tissue surface, to give a visual indication that the distal end of the microsurgical tool is in proximity to the tissue surface. The distal portion of the distance indication member can be further configured to return to a non-deflected configuration when no longer in contact with the tissue surface.

Disclosed herein are sealing devices configured for improving sealing functionality with an engaged extension member of an apparatus. More specifically, disclosed herein are trocar sealing devices configured for improving insufflation gas containment in relation to trocars (and/or other related type of devices) that are used for enabling a surgical instrument such, for example, a laparoscope, to gain access to an abdominal cavity (or other body cavity). By providing for such improved insufflation gas containment, sealing devices as disclosed herein are particularly advantageous, desirable and useful in view of long-standing reasons for limiting insufflation gas leakage and in view of newly recognized reasons stemming from outbreak of COVID-19 disease for limiting insufflation gas leakage.

Disclosed is a fixing bone plate, which comprises a plate body. The plate body is provided with a plate main part and a locking portion passing through the plate body. The plate main part is connected to the locking portion at the corresponding two ends of the plate body. The fixing bone plate also comprises an attachment portion. The attachment portion is provided with a bone attachment surface. The attachment portion is disposed on the other side of the locking portion. The plate body can be manufactured by using a metal laser additive manufacturing technique or a 3D metal printing technique. The fixing bone plate can be accurately positioned and stably combined with a human bone according to morphological characteristics of bones.

Disclosed is a fixing bone plate, which comprises a plate body. The plate body is provided with a plate main part and a locking portion passing through the plate body. The plate main part is connected to the locking portion at the corresponding two ends of the plate body. The fixing bone plate also comprises an attachment portion. The attachment portion is provided with a bone attachment surface. The attachment portion is disposed on the other side of the locking portion. The plate body can be manufactured by using a metal laser additive manufacturing technique or a 3D metal printing technique. The fixing bone plate can be accurately positioned and stably combined with a human bone according to morphological characteristics of bones.

The present invention provides for implant device delivery apparatuses and related methods of use. The delivery systems of the present invention incorporate a stretch resistant tube that advantageously makes the implant device, such as an embolic coil, stretch resistant while a delivery system is being used to position the implant device at a desired target site.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (c) analysing said spectrometric data in order to identify and/or characterise said target cell population or one or more cells and/or compounds present in said target cell population.

A tool for cleaning a vertebral disc includes an elongated hollow shaft including a proximal end and a distal end; a first drum rotatably disposed in a housing secured to the proximal end of the shaft, the first drum having a first axis; a second drum rotatably disposed proximate the distal end of the shaft, the second drum having a second axis parallel to the first axis; and a belt extending through the hollow shaft and operatively coupled to the first drum and the second drum, the belt comprising a plurality of teeth configured to cut anatomical tissue, each tooth of the plurality of teeth remaining flush with an outer surface of the belt when a section of the belt comprising the tooth is substantially straight, and projecting beyond the outer surface when the section of the belt bends around the first drum or the second drum.

A catheter assembly includes a catheter comprising a flexible elongated member including a distal portion that includes a tubular body defining an inner lumen and a plurality of body apertures that extend through a sidewall of the tubular body into the inner lumen, and a plurality of primary electrodes positioned along the tubular body. The catheter assembly includes a wire defining at least one secondary electrode, the wire being configured to be slidably moved through the inner lumen of the tubular body, where the wire and the plurality of primary electrodes are configured to electrically couple to an energy source that delivers an electrical pulse to a fluid in contact with the plurality of primary electrodes and the at least one secondary electrode to cause the fluid to undergo cavitation to generate a pressure pulse wave within the fluid.

A holding arm for holding a surgical mechatronic assistance system or a surgical instrument is described. The holding arm includes a proximal end for attaching the holding arm to a base and a distal end for receiving the surgical mechatronic assistance system or the surgical instrument. The holding arm also includes a first arm segment connected to a first joint and a second arm segment connected to a second joint. The first joint and the second joint are releasable and lockable. The holding arm also includes a switch adapted to release both the first and second joints. The holding arm also includes a first contacting device with two contact elements arranged substantially opposite one another on the first arm segment. The first contacting device is adapted to release the first joint only when both of the two contact elements of the first contacting device are contacted.