A holding arm for holding a surgical mechatronic assistance system or a surgical instrument is described. The holding arm includes a proximal end for attaching the holding arm to a base and a distal end for receiving the surgical mechatronic assistance system or the surgical instrument. The holding arm also includes a first arm segment connected to a first joint and a second arm segment connected to a second joint. The first joint and the second joint are releasable and lockable. The holding arm also includes a switch adapted to release both the first and second joints. The holding arm also includes a first contacting device with two contact elements arranged substantially opposite one another on the first arm segment. The first contacting device is adapted to release the first joint only when both of the two contact elements of the first contacting device are contacted.

Spinal device/implants are provided, comprising a spinal device/implant and a sensor.

Spinal device/implants are provided, comprising a spinal device/implant and a sensor.

An apparatus includes a cylindraceous sleeve body, a navigation sensor, and an interface feature. The cylindraceous sleeve body includes an open proximal end, an open distal end, and a lumen extending from the open proximal end to the open distal end. The lumen is sized and configured to receive a shaft of a medical instrument. The navigation sensor is positioned at the open distal end of the cylindraceous sleeve body. The interface feature is configured to couple the navigation sensor with an image guidance system. The navigation sensor is configured to cooperate with an image guidance system to provide feedback indicating a position of the navigation sensor in three-dimensional space.

The disclosed technology provides a device for sealing an aperture in a tissue of a body lumen. The device comprises a flexible support member having a base having (i) a central portion and (ii) one or more lateral support portions, to engage and/or hold a sealable member of the device against an interior surface of the tissue when the device is in the sealing position. The lateral support portions provide additional support surfaces to engage peripheral portions of the sealable member against the interior surface of the tissue.

A system for preventing relative motion between bones or sections of bone, for example, an ilium and a sacrum. The system includes an insertion tool and an implant. The implant includes a trunk, a distal anchor, a proximal anchor, and a stem coupled to the trunk. A driver of the insertion tool receives an input for a drive shaft of the insertion tool to draw the stem proximally such that the trunk is drawn towards the insertion tool. The drawing of the trunk and engagement of first and second engagement features is configured to deploy the proximal anchor outwardly. The distal anchor may be an expandable member, and the implant may define a bore extending through the proximal anchor for the distal anchor to receive injectable material. The system may be cannulated such that the insertion tool and the implant may be directed over a guidewire to position the implant.

A prosthetic heart valve may include a stent, a valve assembly disposed within the stent, a flange, and a plurality of anchor arms coupled to the stent. The stent may have collapsed and expanded conditions and inflow and outflow ends. The flange may include a plurality of braided wires and may be coupled to the stent and may be positioned adjacent the inflow end of the stent in the expanded condition of the stent. Each anchor arm may have a first end coupled to the stent adjacent the outflow end of the stent, a second end coupled to the stent adjacent the outflow end of the stent, and center portions extending from the first and second ends toward the inflow end of the stent. The center portions may be joined together to form a tip pointing toward the inflow end of the stent in the expanded condition of the stent.

An applicator is provided for a flowable media, particularly an adhesive contained in a container and the applicator includes an elongate body member having an internal cavity that holds the container. The cavity has a distal end with a breaking means that is actuated by an axial force. Various embodiments of the actuator are shown to apply the force, including a wire cracker and a molded integral handle member with a lever linkage that bears against a ram which holds the ampoule and having a spring arm that rides within the cavity to oppose a pivoting force on the handle. These embodiments also enable single handed use.

A mesenchymal stem cell harvesting system and method for increasing the efficiency of collecting and processing physiological fluids containing mesenchymal stem cells from a cavity within a patient’s skeletal system. Microenvironments risk in MSC production and concentration within a cavity, for example the patient’s ilium, are penetrated with a pointed instrument used to create an aperture in the hard cortical bone forming the cavity followed by the insertion of an aspiration device which extracts one or more samples of cancellous bone, bone marrow, bone marrow blood and other aspirated material. The aspirate is rinsed and may be filtered to remove unwanted material and to increase the concentration and purity of the mesenchymal stem cells in the aspirant far beyond levels formerly obtainable for use in autologous treatment of the patient.

An implantable closure device for sealing an opening through a biologic tissue membrane against leakage of biological fluid includes a fluid sealing plug configured to be positioned within the opening. One or more retainer sections are configured to secure the fluid sealing plug within the opening. The retainer sections include at least one of a distal retainer section coupled to a distal end of the fluid sealing plug and configured to be disposed distally on the biologic tissue membrane, or a proximal retainer section coupled to a proximal end of the fluid sealing plug and configured to be disposed proximally on the biologic tissue membrane.