A cooling radiofrequency ablation probe for delivering electrical and thermal energy to tissue of a patient's body is provided. The probe comprises a handle having an upper portion, a lower portion, and a Luer connector. The probe further comprises an extended electrocap assembly interfacing with one end of the handle, and a cable-tubing assembly interfacing with another end of the handle. The cable-tubing assembly includes an electrical cable that terminates at an electrical connector and a dual-lumen fluid tubing that terminates at inlet and outlet fluid connectors. An active tip of the extended electrocap assembly is configured to deliver the electrical and thermal energy to the tissue of the patient's body.

An ultrasonic surgical instrument and method of deflecting an end effector include an acoustic waveguide with a proximal waveguide body portion defining a longitudinal axis, a distal waveguide body portion having an ultrasonic blade distally projecting therefrom, and an articulation body portion extending between the proximal and distal waveguide body portions. The articulation body portion of the acoustic waveguide is configured to flex a first direction to thereby deflect the ultrasonic blade relative to the longitudinal axis and through a first plane. In addition, the articulation body portion of the acoustic waveguide is further configured to flex a second direction to thereby deflect the ultrasonic blade relative to the longitudinal axis and through a second plane. The second direction is different than the first direction such that the second plane is different than the first plane for multiplanar deflection of the ultrasonic blade relative to the longitudinal axis.

The device comprises an outer conductor (7) and an inner conductor (9) arranged approximately coaxial with each other. The outer conductor surrounds the inner conductor. The outer conductor (7) and the inner conductor (9) are arranged and configured to generate an electromagnetic field with lines of force extending from a front surface (9A) of the inner conductor (9) to a front surface (7C) of the outer conductor (7). The device further comprises an energy delivery window (13) arranged in front of the outer conductor and the inner conductor.

The present disclosure relates to methods, devices, kits and systems for enhancing the efficacy and longevity of denervation procedures.

Embodiments discussed herein facilitate generation of a prognosis for recurrence or non-recurrence of atrial fibrillation (AF) after pulmonary vein isolation (PVI). A first set of embodiments discussed herein relates to training of a machine learning classifier to determine a prognosis for AF after PVI based on radiographic images, alone or in combination with clinical features. A second set of embodiments discussed herein relates to determination of a prognosis for a patient for AF after PVI based on radiographic images, alone or in combination with clinical features.

A microwave ablation system and method include an elongate microwave ablation probe. The probe has a radiating portion for performing microwave ablation. The probe includes a first electrode and a second electrode located along the probe body. A radiofrequency energy source is connected to the first and second electrodes. An impedance of tissue is measured using the first and second electrodes. The impedance is used to detect a change in tissue due to microwave ablation of the tissue. Therapy parameters for the microwave ablation procedure can be adjusted in response to the measured impedance. In some examples, one of the electrodes is proximal and one electrode is distal to the radiating portion.

A surgical device including a handle assembly, an elongated portion, an end effector, a drive shaft, and a wick is disclosed. The wick is disposed within an outer sleeve of the elongated portion and is made from a fibrous material. The wick is configured to transfer moisture from a first portion of the wick to a second portion of the wick.

A surgical smoke evacuation system includes a smoke evacuator, a suction instrument, a suction conduit, and a disinfecting device. The smoke evacuator includes a suction generator configured to create a vacuum force. The suction instrument is configured to couple to the smoke evacuator via the suction conduit. The disinfecting device is operably coupled to the suction conduit or the smoke evacuator. The disinfecting device includes a housing defining an inner chamber, an inlet extending from a distal end of the housing and in fluid communication with the inner chamber, an outlet extending from a proximal end of the housing and in fluid communication with the inner chamber, and an ultraviolet light emitting diode board. The ultraviolet light emitting diode board includes at least one ultraviolet-c light emitting diode disposed in the inner chamber and configured to disinfect surgical smoke within the inner chamber.

A surgical smoke evacuation system includes a smoke evacuator, a suction instrument, a suction conduit, and a disinfecting device. The smoke evacuator includes a suction generator configured to create a vacuum force. The suction instrument is configured to couple to the smoke evacuator via the suction conduit. The disinfecting device is operably coupled to the suction conduit or the smoke evacuator. The disinfecting device includes a housing defining an inner chamber, an inlet extending from a distal end of the housing and in fluid communication with the inner chamber, an outlet extending from a proximal end of the housing and in fluid communication with the inner chamber, and an ultraviolet light emitting diode board. The ultraviolet light emitting diode board includes at least one ultraviolet-c light emitting diode disposed in the inner chamber and configured to disinfect surgical smoke within the inner chamber.

Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.