The present invention provides transseptal puncture devices configured to access structures on the left side of the heart from the right side of the heart without requiring open-heart surgery. The devices have adjustable stiffness to enter the vasculature in a flexible, atraumatic fashion, then become rigid once in place to provide a stable platform for penetration of the fossa ovalis. The devices are further configured to controllably and stably extend a needle to puncture the FO. The devices include an indwelling blunt stylus that can extend perpendicularly from the device to increase the accuracy of placement near the fossa ovalis.

The present invention relates to a pathology treatment apparatus comprising: an ultrasound generator device (1), a remote control unit (2) for delivering electricity to the device (1) during at least an activation cycle and determining and controlling the operating parameters thereof, each activation cycle (50) being preceded by a standby cycle, means (31, 32) of electrical connection between the device (1) and the control unit (2), notable in that the control unit (2) is programmed to detect a fault with the electrical connection between the device (1) and the said control unit (2) during at least a standby cycle.

The present invention relates to a pathology treatment apparatus comprising: an ultrasound generator device (1), a remote control unit (2) for delivering electricity to the device (1) during at least an activation cycle and determining and controlling the operating parameters thereof, each activation cycle (50) being preceded by a standby cycle, means (31, 32) of electrical connection between the device (1) and the control unit (2), notable in that the control unit (2) is programmed to detect a fault with the electrical connection between the device (1) and the said control unit (2) during at least a standby cycle.

A vibration transmitter includes: a proximal end extending portion; a supported portion; a distal end extending portion; a first relay unit provided between the supported portion and the proximal end extending portion; and a second relay unit provided between the supported portion and the distal end extending portion. The second relay unit includes a horn that is constructed such that an outer diameter at a position continuously adjacent to the supported portion is larger than: (i) an outer diameter of the first relay unit at a position continuously adjacent to the supported portion, and (ii) the outer diameter of the distal end extending portion. The horn expands amplitude of vibration output from a distal end of the distal end extending portion to be larger than a maximum amplitude at an antinode of vibration in the first relay unit or the proximal end extending portion.

A vibration transmitter includes: a proximal end extending portion; a supported portion; a distal end extending portion; a first relay unit provided between the supported portion and the proximal end extending portion; and a second relay unit provided between the supported portion and the distal end extending portion. The second relay unit includes a horn that is constructed such that an outer diameter at a position continuously adjacent to the supported portion is larger than: (i) an outer diameter of the first relay unit at a position continuously adjacent to the supported portion, and (ii) the outer diameter of the distal end extending portion. The horn expands amplitude of vibration output from a distal end of the distal end extending portion to be larger than a maximum amplitude at an antinode of vibration in the first relay unit or the proximal end extending portion.

A medical probe includes a shaft for navigation in a patient body, and first and second deflection mechanisms. The shaft ends with a flexible section and a spring, followed by a rigid distal tip having one or more medical devices coupled thereto. The first deflection mechanism is configured to deflect the flexible section relative to the shaft. The second deflection mechanism is configured to deflect the distal tip relative to the first flexible section by using the spring.

Sphincterotomes and methods for making and using sphincterotomes are disclosed. An example sphincterotome may include an elongate shaft having an outer surface and a distal end region. The sphincterotome may also include a sphincterotome wire assembly having a distal end coupled to the distal end region of the elongate shaft and a body portion extending along the outer surface of the elongate shaft. The sphincterotome wire assembly may be designed to shift the distal end region of the elongate shaft between a first configuration and a curved configuration. The body portion of the sphincterotome wire assembly may include a cutting region and a non-conductive region.

The device includes an outer conductor and an inner conductor arranged approximately coaxial with each other. The outer conductor surrounds the inner conductor. The outer conductor and the inner conductor are arranged and configured to generate an electromagnetic field with lines of force extending from a front surface of the inner conductor to a front surface of the outer conductor. The device further includes an energy delivery window arranged in front of the outer conductor and the inner conductor.

There is provided a phototherapy apparatus, in which the therapeutic light is delivered through one or more massage components. The massage component provides mechanical massage to the subject biological tissue and modifies the properties of the subject tissue in thickness, density, etc. to facilitate the absorption of the therapeutic light and enhance the effect of the phototherapy procedure. The light source of the phototherapy apparatus is actively cooled by a synthetic jet cooler.

Devices, systems, and methods for the localization of body lumen junctions and other intraluminal structure are disclosed. Various embodiments permit clinicians to identify the locations of intraluminal structures and medical devices during non-surgical medical techniques, by determining the conductance and/or cross-sectional area at a plurality of locations within the body lumen.