Estimating parental contribution of ancestry includes: obtaining a set of ancestry assignment data associated with an individual's genotype data, at least some of the ancestry assignment data indicating that one or more segments of the individual's genotype data is deemed to be associated with a specific ancestry; determining whether in the individual's genotype data there is at least one confirmed region of overlapping ancestry assignment associated with the specific ancestry; in the event that it is determined that there is at least one confirmed region of overlapping ancestry assignment associated with the specific ancestry: specifying that parental contribution of the specific ancestry is made by both parents of the individual; in the event that it is determined that there is no confirmed region of overlapping ancestry assignment associated with the specific ancestry: statistically determining whether the parental contribution to the specific ancestry is made by only one parent of the individual or by both parents of the individual, the determination being based at least in part on one or more lengths of the one or more segments deemed to be associated with the specific ancestry; and outputting information pertaining to the parental contribution to the specific ancestry.

The invention provides methods of predicting the weight loss propensity of an animal of the genus Equus, through the assessment of various markers in a sample obtained from the animal. Such markers include fermentation products and/or metabolites thereof such as volatile fatty acids, indicators of bacterial population diversity, and the abundance/relative abundance of specific bacterial taxa.

The invention provides methods of predicting the weight loss propensity of an animal of the genus Equus, through the assessment of various markers in a sample obtained from the animal. Such markers include fermentation products and/or metabolites thereof such as volatile fatty acids, indicators of bacterial population diversity, and the abundance/relative abundance of specific bacterial taxa.

The invention provides an analysis method and a device for determining a haplotype of a descendant object. Particularly, the invention provides a data analysis method for determining a haplotype genetic flow, comprising the following steps: (a) providing data sets for the analysis, the data sets being data sets related to genome information; (b) performing molecular marker genotyping in the upstream and downstream regions of Y1 target sites in each of the data sets, thereby obtaining molecular marker genotyping data, wherein Y1 is a positive integer greater than or equal to 1; (c) constructing a binary genetic vector of (0, 1) for each molecular marker site upstream and downstream of each target site in each of the data sets; (d) determining a maximum likelihood estimation value L using a Hidden Markov model for each target site; (e) determining a haplotype genetic flow direction of the descendant object and the family members through a Viterbi dynamic programming algorithm.

The present disclosure provides compositions and methods, as well as combinations, kits, and systems that include the compositions and methods, for amplification, detection, characterization, assessment, profiling and/or measurement of nucleic acids in samples, particularly biological samples. Compositions and methods provided herein include combinations of microbial species target-specific nucleic acid primers for selective amplification and/or combinations of primers for amplification of nucleic acids from a large group of taxonomically related microorganisms. In one aspect, amplified nucleic acids obtained using the compositions and methods can be used in various processes including nucleic acid sequencing and used to detect the presence of microbial species and assess microbial populations in a variety of samples. In accordance with the teachings and principles, new methods, systems and non-transitory machine-readable storage medium are provided to compress reference sequence databases used in mapping sequence reads for analysis and profiling of microbial populations.

Techniques are described that facilitate determining potential cancer gene therapy targets by joint modeling of cancer survival events. In one embodiment, a computer-implemented comprises employing, by a device operatively coupled to a processor, a multi-task learning model to determine active genetic factors respectively associated with different types of cancer based on cancer survival data and patient genomic data for groups of patients that respectively survived the different types of cancer. The computer-implemented method further comprises, determining, by the device, common active genetic factors of the active genetic factors that are shared between two or more types of cancer of the different types of cancer.

Methods for non-invasive prenatal paternity testing are disclosed herein. The method uses genetic measurements made on plasma taken from a pregnant mother, along with genetic measurements of the alleged father, and genetic measurements of the mother, to determine whether or not the alleged father is the biological father of the fetus. This is accomplished by way of an informatics based method that can compare the genetic fingerprint of the fetal DNA found in maternal plasma to the genetic fingerprint of the alleged father.

Methods for non-invasive prenatal paternity testing are disclosed herein. The method uses genetic measurements made on plasma taken from a pregnant mother, along with genetic measurements of the alleged father, and genetic measurements of the mother, to determine whether or not the alleged father is the biological father of the fetus. This is accomplished by way of an informatics based method that can compare the genetic fingerprint of the fetal DNA found in maternal plasma to the genetic fingerprint of the alleged father.

The present disclosure provides methods for trait introgression involving crossing a donor plant comprising a trait of interest to an intermediate recurrent parent plant followed by crossing of the intermediate recurrent parent plant to one or more recipient parent plants. The present method may be used to introgression a desired trait of interest into the genome of an elite cultivar in fewer backcross generations, thereby accelerating new line production and reducing costs.

The invention(s) include systems and methods for receiving and processing agriculture-associated samples with sample processing architecture structured to rapidly return outputs characterizing effects of agriculture inputs and practices over time. Control instructions based upon outputs of the systems and methods are then executed for maintaining or improving performance of crops and agriculture sites (e.g., in relation to yield, in relation to nutrient characteristics) in a sustainable manner (e.g., environmentally sustainable manner). System and method outputs can further be used to affect modifications to product treatments generated by associated manufacturers.