A system for providing structural variation or phasing information is provided. The system accesses a nucleic acid sequence dataset corresponding to a target nucleic acid in a sample. The dataset comprises a header, synopsis, and data section. The data section comprises a plurality of sequencing reads. Each sequencing read comprises a first portion corresponding to a subset of the target nucleic acid and a second portion that encodes an identifier for the sequencing read from a plurality of identifiers. One or more programs in the memory of the system use a microprocessor of the system to provide a haplotype visualization tool that receives a request for structural variation or phasing information from the dataset. The request is evaluated against the synopsis thereby identifying portions of the data section. Structural variation or phasing information is formatted for display in the haplotype visualization tool using the identified portions of the data section.

A system for providing structural variation or phasing information is provided. The system accesses a nucleic acid sequence dataset corresponding to a target nucleic acid in a sample. The dataset comprises a header, synopsis, and data section. The data section comprises a plurality of sequencing reads. Each sequencing read comprises a first portion corresponding to a subset of the target nucleic acid and a second portion that encodes an identifier for the sequencing read from a plurality of identifiers. One or more programs in the memory of the system use a microprocessor of the system to provide a haplotype visualization tool that receives a request for structural variation or phasing information from the dataset. The request is evaluated against the synopsis thereby identifying portions of the data section. Structural variation or phasing information is formatted for display in the haplotype visualization tool using the identified portions of the data section.

A system and method to a power production cycle optimized for combusting fractionated solid biomass such that the fractionated solid biomass is transported in a solvent that is utilized in a solvent-enhanced biomass liquefaction conversion process and the solvent is subsequently fractionated from the fractionated solid biomass for direct use as a liquid fuel for transport vehicles to maximize energy density and total system energy efficiency. Utilizing the solvent as a waste heat recovery method prior to combustion by the transport vehicle increases the total system energy efficiency and maximizes biomass value creation.

A system and method to a power production cycle optimized for combusting fractionated solid biomass such that the fractionated solid biomass is transported in a solvent that is utilized in a solvent-enhanced biomass liquefaction conversion process and the solvent is subsequently fractionated from the fractionated solid biomass for direct use as a liquid fuel for transport vehicles to maximize energy density and total system energy efficiency. Utilizing the solvent as a waste heat recovery method prior to combustion by the transport vehicle increases the total system energy efficiency and maximizes biomass value creation.

A device for compressing subject data, the device comprises a communication link, the communication link capable of receiving a set of subject data; a compression module, the compression module configured to apply a compression algorithm to the set of subject data, the compression algorithm compressing the set of subject data using a reference string of subject data; and a transmission module, the transmission module configured to transmit the compressed subject data. The device further comprising an encryption module for encrypting the subject data.

A device for compressing subject data, the device comprises a communication link, the communication link capable of receiving a set of subject data; a compression module, the compression module configured to apply a compression algorithm to the set of subject data, the compression algorithm compressing the set of subject data using a reference string of subject data; and a transmission module, the transmission module configured to transmit the compressed subject data. The device further comprising an encryption module for encrypting the subject data.

A method includes generating a faulted point cloud representing a faulted geological formation including a first fault block having a first surface, a second fault block having a second surface, and a fault formed therebetween and having a fault surface, generating a first fault trace from an intersection of the first surface and the fault surface and a second fault trace from an intersection of the second surface and the fault surface, generating a first fault polygon using the first and second fault traces, generating a center polyline, generating third and fourth fault traces separated from the first and second fault traces, respectively, generating a second fault polygon using the third and fourth fault traces, expanding a first area including the first and third fault traces, expanding a second area including the second and fourth fault traces, and generating an unfaulted point cloud representing an unfaulted geological formation.

The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X.sup.1 represents NH or CH, X.sup.2 represents CH or N, R.sup.1 and R.sup.2 each represent a C.sub.1 to C.sub.6 alkoxy group or the like, R.sup.3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R.sup.4 represents a C.sub.1 to C.sub.6 alkylthio group or a C.sub.2 to C.sub.6 alkenyl group (the C.sub.1 to C.sub.6 alkylthio group and the C.sub.2 to C.sub.6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like. ##STR00001##

The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X.sup.1 represents NH or CH, X.sup.2 represents CH or N, R.sup.1 and R.sup.2 each represent a C.sub.1 to C.sub.6 alkoxy group or the like, R.sup.3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R.sup.4 represents a C.sub.1 to C.sub.6 alkylthio group or a C.sub.2 to C.sub.6 alkenyl group (the C.sub.1 to C.sub.6 alkylthio group and the C.sub.2 to C.sub.6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like. ##STR00001##

This document describes, among other things, a computer-implemented method for displaying and analyzing sequenced genome data. The method can include obtaining, at a computing system, genomic data for a plurality of organisms. A graphical representation can of the genomic data can be generated by the computing system based at least on the genomic data for the plurality of organisms, and the graphical representation can include a plurality of tracks that are arranged to show one or more features of the genomic data for different ones of the plurality of organisms. The graphical representation can be output for display by the computing system.