A peristaltic pump is disclosed that includes a plunger, a spring, an actuator, a position sensor, and a processor. The plunger actuates toward and away from a tube. The spring biases the plunger toward the tube. The actuator actuates the plunger away from the tube and mechanically engages and disengages from the plunger. The position sensor senses a position of the plunger. The processor receives the sensed position of the plunger and estimates fluid flow within the tube using a first position of the plunger when the actuator is engaged with the plunger and a second position of the plunger when the actuator is disengaged from the plunger.

Systems and methods are provided for identifying and rendering content relevant to a user's current mental state and context. In an aspect, a system includes a state component that determines a state of a user during a current session of the user with the media system based on navigation of the media system by the user during the current session, media items provided by the media system that are played for watching by the user during the current session, and a manner via which the user interacts with or reacts to the played media items. In an aspect, the state of the user includes a mood of the user. A selection component then selects a media item provided by the media provider based on the state of the user, and a rendering component effectuates rendering of the media item to the user during the current session.

An at-home medical diagnostic test kit container including a plurality of at-home medical diagnostic test kits is provided herein. In particular, the medical diagnostic test kit container may include a machine-readable code (e.g., QR code) configured to facilitate an augmented reality experience associated with the at-home medical diagnostic test kit container. In some embodiments, a testing and diagnostic platform may facilitate tracking of inventory within the at-home medical diagnostic test kit container and/or may facilitate coordination of prescription medication order fulfillment and delivery upon indication of a medical condition that could benefit from taking prescription medication.

An image generation device derives, for a subject including a specific structure, a subject model representing the subject by deriving each feature amount of the target image having the at least one representation format and combining the feature amounts based on the target image. A latent variable derivation unit derives a latent variable obtained by dimensionally compressing a feature of the subject model according to the target information based on the target information and the subject model. A virtual image derivation unit outputs a virtual image having the representation format represented by the target information based on the target information, the subject model, and the latent variable.

A medication compliance and drug abuse prevention device for use as a cap with conventional medication container. The neck of the cap is adapted for mating with the neck of any conventional medication container. The mating of the cap neck with the container neck forms a seal therebetween and the seal can be maintained in a locked or unlocked state as per requirement. The cap has a weighment module configured to measure a mass of a medicinal substance contained inside the container. A control module determines a difference in the mass of the medicinal substance measured before and after the unlocked state and initiate one or more alert actions if the difference in mass of the medicinal substance is found to be less than or more than a prescribed mass of medicinal substance.

The present disclosure provides systems, apparatuses and methods that provide probe-cavity location and motion data based on probe location and respiration data.

A technique relates to coronary reconstruction. Angiogram data associated with cardiac catheterization of an artery for a subject is received, where a contrasting agent is used during the cardiac catheterization. Frames that match from the angiogram data are selected, the frames being from different views. Two-dimensional ordered point clouds for the frames are formed. A three-dimensional ordered point cloud of a reconstructed coronary artery for the subject from the two-dimensional ordered point clouds of the frames is formed. Observed contrast motion caused by the contrasting agent onto the reconstructed coronary artery is mapped, the reconstructed coronary artery thereby providing a three-dimensional model of the artery of the subject during the cardiac catheterization.

A technique relates to coronary reconstruction. Angiogram data associated with cardiac catheterization of an artery for a subject is received, where a contrasting agent is used during the cardiac catheterization. Frames that match from the angiogram data are selected, the frames being from different views. Two-dimensional ordered point clouds for the frames are formed. A three-dimensional ordered point cloud of a reconstructed coronary artery for the subject from the two-dimensional ordered point clouds of the frames is formed. Observed contrast motion caused by the contrasting agent onto the reconstructed coronary artery is mapped, the reconstructed coronary artery thereby providing a three-dimensional model of the artery of the subject during the cardiac catheterization.

An apparatus and a method for assessing a vasculature is provided in which a time series of diagnostic images is used in combination with at least one boundary parameter associated with said time series to determine a quantitative fluid dynamics parameter indicative of the fluid flow through the vasculature using a trained classifier. By providing both, the time series of diagnostic images and the at least one boundary parameter to the determination, it is ensured that the classifier is provided with consistent data allowing for a more accurate determination of the quantitative fluid dynamics parameter.

Provided herein are methods for classifying how a subject having a cancer will respond to immunotherapeutic (IT) therapy based on the subject's immunosignature or frameshift signature. Also provided herein are methods for classifying a subject having a cancer as having a good prognosis or a poor prognosis based on the subject's immunosignature or frameshift signature.