The present invention is directed to composite nanoparticles comprising a metal, a rare earth element, and, optionally, a complexing ligand. The invention is also directed to composite nanoparticles having a core-shell structure and to processes for preparation of composite nanoparticles of the invention.

A method of preparing a coated nanoparticle can include decomposing a compound to produce a nanoparticle, oxidizing the nanoparticle to produce an oxidized nanoparticle, and coating the oxidized nanoparticle with a zwitterionic ligand to produce the coated nanoparticle. The coated nanoparticle or the nanoparticle can be used in magnetic resonance imaging.

The present invention relates to MASP-3 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-3 dependent complement activation.

The present invention relates to a method of manufacturing a superparamagnetic nanocomposite and a superparamagnetic nanocomposite manufactured using the same, and more particularly to a method of manufacturing a superparamagnetic nanocomposite suitable for use in magnetic separation for the detection of a target biomaterial and a superparamagnetic nanocomposite manufactured using the same. The method of manufacturing the superparamagnetic nanocomposite according to the present invention has a higher yield and a high rate without complicated processing than a conventional method of manufacturing a magnetic nanoparticle for magnetic separation and is capable of mass production of the superparamagnetic nanocomposite having excellent properties with uniform size and particle size distribution, high aqueous solution dispersibility and high magnetization and being capable of maintaining superparamagnetism.

The disclosure provides improved magnetic glass particles for use in nucleic acid capture, enrichment, analysis, and/or purification. Various modifications to the disclosed compositions and methods of using the same, as well as devices and kits are described.

Composition for making magnetic coverings comprising at least one elastomer, at least one magnetic filler, at least one compatibilizer, wherein the at least one magnetic filler is present in the composition in an amount comprised between 90% and 300% by weight, preferably between 100% and 250% by weight based on the weight of the least one elastomer.

Discrete, individualized carbon nanotubes having targeted, or selective, oxidation levels and/or content on the interior and exterior of the tube walls are claimed. Such carbon nanotubes can have little to no inner tube surface oxidation, or differing amounts and/or types of oxidation between the tubes' inner and outer surfaces. These new discrete carbon nanotubes are useful in treatment compositions for contaminated soil and ground water. Additives such as plasticizers, can be used in compounding and formulation of elastomeric, thermoplastic and thermoset composite for improvement of mechanical, electrical and thermal properties.

The present invention relates to a water-soluble polymer complex that includes a water-soluble block copolymer and a magnetic nanoparticle, wherein the water-soluble polymer complex has a nonzero net magnetic moment in the absence of an applied magnetic field at ambient temperatures. The water-soluble block copolymer is preferably a diblock or triblock copolymer and the magnetic nanoparticle is preferably a ferrimagnetic or ferromagnetic nanoparticle. The water-soluble complexes may be derivatized with reactive groups and conjugated to biomolecules. Exemplary water-soluble polymer complexes covered under the scope of the invention include PEG.sub.112-b-PAA.sub.40 modified CoFe.sub.2O.sub.4; NH.sub.2-PEG.sub.112-b-PAA.sub.40 modified CoFe.sub.2O.sub.4; PNIPAM.sub.68-b-PAA.sub.28 modified CoFe.sub.2O.sub.4; and mPEG-b-PCL-b-PAA modified CoFe.sub.2O.sub.4.

A production method for metal oxide particles includes: obtaining precursor particles of a metal oxide by performing a synthesis reaction of the precursor particles in the presence of an organic compound; and converting the obtained precursor particles into metal oxide particles by heating an aqueous solution containing the precursor particles to 300 C. or higher and pressurizing the aqueous solution at a pressure of 20 MPa or higher.

A chamber (422) for a cryostat (420) includes: first and second annular sections (4221, 4222) separated and spaced apart from each other along a first direction, and a third annular section (4223) extending in the first direction between the first and second annular sections and connecting the first and second annular sections to each other. The first and second annular sections define corresponding first and second internal volumes, the third annular section defines a third internal volume, and the third internal volume is substantially less than the first internal volume and substantially less than the second internal volume.