It is disclosed a System for sampling tissue from an ear of an animal including: —a male component (2) including a detachable sample collecting part (2b), comprising a cavity (2c) for collecting the sample and a cutting edge (2a) at an aperture of the cavity (2c) for cutting the sample from the animal ear; and —a tissue sample container (3) including a container component (30) for receiving the sample collecting part (2b) and the tissue sampled, the container component (30) having an opening (30b) closed by a sealed membrane or a cover (30d).

The tissue sample container (3) includes —a ring (31) comprising a peripheral flange (31a), a protrusion (31b) and radial portions (31c), the radial portions (31c) supporting the protrusion (31b) in the middle of the peripheral flange (31a) of the ring (31); —a moulded portion (32) around the peripheral edge (31a) of the ring (31) and the container component (30), to embed the ring (31) and the container component (30) above the sealed membrane or cover (30d), preventing detachment thereof, wherein the protrusion (31b) projects from the middle of the ring (31) in a direction opposite with respect to the container component (30) and wherein a length of the protrusion (31b) is equal to or minor than a depth of the cavity (2c) of the sample collecting part (2b) to enter entirely the cavity (2c) through the aperture thereof so as the cutting edge (2a) contacts the radial portions (31c) for cutting them at a predetermined portion (31cc) during use, when the sample collecting part (2b) is moved in a same axis along which the protrusion (31b) is arranged.

It is disclosed a system (1) for sampling tissue from an ear of an animal including: —a male component (2) including an engagement profile (2c) and a detachable sample collecting part (2b) with a cutting edge (2a); —a female component including a hole (4b) and retaining means (4a) for retaining the engagement profile (2c) of the male component (2), once the engagement profile (2c) has passed the hole (4b); —a tissue sample container (3) including an opening (3b) arranged below the hole (4b) of the female component (4b), for receiving the sample collecting part (2b) and the tissue sampled, the opening (3b) being closed by a sealed membrane or a cover (3d). The tissue sample container (3) includes a protrusion (3c) arranged at least in part in the hole (4b) of the female component (4).

An energy delivery system includes an RF synthesizer circuit configured to generate an RF electric signal and a preamplification stage operably coupled to the RF synthesizer circuit. The preamplification stage has at least one attenuator. A board controller is operably coupled to the attenuator of the preamplification stage that is configured to modify a gain setting of the attenuator. An output connection is configured to provide a low-power signal or a high-power signal based on at least the RF electric signal and the gain setting. The low-power signal or high-power signal is provided to an RF applicator configured to couple an alternating RF electric field to animal tissue.

Canalicular occlusion devices are described comprising an occlusive element and a memory frame comprising a memory material. The occlusive element is configured to substantially prevent fluid from flowing through portions of the canaliculus. Also disclosed are methods of occluding a canalicular system with the devices of the present invention.

The present invention is directed to guides for use in anastomotic procedures, and in particular in small intestine anastomosis. An anastomotic guide of the invention preferably comprises a tubular body comprising a wall having an abluminal surface, a luminal surface and two ends; the wall comprising at least one sheet of a biocompatible material in a laminate structure having two or more layers, the layers of the laminate structure being joined by a water soluble adhesive polymer, the tubular body being insertable into the lumen of an organ having a luminal surface so that the abluminal surface of the anastomotic guide contacts the luminal surface of the organ.

A device and method for perforating a dense bone layer. The device includes a vibration generator for generating mechanical vibration, in particular ultrasonic vibration, and an instrument with an elongated shaft and a distal end piece including a perforator. The distal end piece is arranged at a distal end of the shaft and the proximal end of the shaft is connected or connectable to the vibration generator. The perforator has the form of a solid or a hollow cylinder. The vibration generator, the shaft and the distal end piece are adapted to each other for the shaft to transmit, when connected to the activated vibration generator, mechanical vibration from the vibration generator to the distal end piece and for vibrating the perforator in a direction parallel to its cylinder axis.

A method of treating a non-human animal subject includes irradiating, one or more times, light having a peak wavelength in a range of 315-335 nm to an affected area of the animal subject.

A device, which may be a veterinary Foley-type urinary catheter for use with feline patients, and more specifically, male feline patients is described herein. The device is of sufficient size to pass through a male feline's urethra and without the need to be sutured in place to secure to the patient. The catheter may include a proximal portion configured to engage accessories, tools and instruments that may pass through the proximal portion into the catheter portion of the device. The proximal portion may include two separate tubular arms that may engage these accessories to allow fluid passage easily through the device as well as the tools and instruments. The catheter portion may be approximately 3 to 5 Fr in diameter and may further include a balloon residing at the distal portion of the catheter. The entire length of the catheter portion may be approximately 22 cm to 36 cm and include a taper toward a distal tip.

Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices may include the use of an RBC flocculant, for example polyDADMAC, and an approximate blood hematocrit from the type of animal blood being evaluated, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal blood hematocrit, and a calculated RBC packing ratio value for the collection device. A collection device with a BIP is disclosed. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

A method for creating an animal model of traumatic optic nerve injury, including fully exposing an internal segment of an optic canal as well as adjacent anterior skull base, posterior ethmoid sinus and lateral sphenoid sinus walls through an ethmoid sinus-sphenoid sinus operation pathway under an endoscope, and impacting different sites of the internal segment of the optic canal with controllable impact force to cause optic nerve injury so as to prepare a controllable and quantifiable TONI bionic elastic injury animal model reflecting contusion to an internal segment of an optic canal in a human TONI clinical injury state. With less intracranial combined injury to the animal, the survival rate is high. Different sites of the optic canal are impacted with quantifiable elastic force for the quantitative and qualitative purposes with respect to the injured parts and the injury degree.