Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “η” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

In one embodiment, the present invention provides an intrauterine device (IUD) comprising an oval shape, wherein the device comprises a core of magnetic material, an inert material or copper coating the core, wherein the coating comprises a pharmaceutical agent, copper or a combination thereof. Another embodiment provides a method to suppress estrus in a subject comprising inserting an intrauterine device (IUD) comprising an oval shape, wherein the device comprises a core of magnetic material and an inert material or copper coating the core.

In one embodiment, the present invention provides an intrauterine device (IUD) comprising an oval shape, wherein the device comprises a core of magnetic material, an inert material or copper coating the core, wherein the coating comprises a pharmaceutical agent, copper or a combination thereof. Another embodiment provides a method to suppress estrus in a subject comprising inserting an intrauterine device (IUD) comprising an oval shape, wherein the device comprises a core of magnetic material and an inert material or copper coating the core.

The invention relates to a method for providing control data for an eye surgical laser of a treatment apparatus for the removal of a tissue from a human or animal cornea. The method includes ascertaining a temperature distribution, which is expected in the cornea per laser pulse, determining a laser pulse sequence of a preset laser pulse distribution for removing the tissue by means of a temperature model of the cornea, wherein a respective laser pulse position in the cornea is preset by the laser pulse distribution and wherein it is preset by the laser pulse sequence, in which order the preset laser pulse positions are irradiated with the respective laser pulses, wherein a temperature profile of the cornea is calculated by means of cumulated temperature distributions of the laser pulses in the temperature model and a difference profile to a preset limit temperature profile is determined, and wherein the order of the laser pulses is ascertained depending on the difference profile for determining the laser pulse sequence, and providing control data for controlling the eye surgical laser, which uses the laser pulse sequence for removing the tissue.

The invention relates to a method for providing control data for an eye surgical laser of a treatment apparatus for the removal of a tissue from a human or animal cornea. The method includes ascertaining a temperature distribution, which is expected in the cornea per laser pulse, determining a laser pulse sequence of a preset laser pulse distribution for removing the tissue by means of a temperature model of the cornea, wherein a respective laser pulse position in the cornea is preset by the laser pulse distribution and wherein it is preset by the laser pulse sequence, in which order the preset laser pulse positions are irradiated with the respective laser pulses, wherein a temperature profile of the cornea is calculated by means of cumulated temperature distributions of the laser pulses in the temperature model and a difference profile to a preset limit temperature profile is determined, and wherein the order of the laser pulses is ascertained depending on the difference profile for determining the laser pulse sequence, and providing control data for controlling the eye surgical laser, which uses the laser pulse sequence for removing the tissue.

A gas mixture apparatus includes a measurement control system, an activation system, a pressurized chamber with one or more gases, and a mixing chamber. A filter can be preattached to the outlet of the mixture apparatus, allowing excess gas to be discharged therethrough and then atmospheric air to be drawn into the mixture apparatus through the filter for creating a therapeutic gas mixture.

A gas mixture apparatus includes a measurement control system, an activation system, a pressurized chamber with one or more gases, and a mixing chamber. A filter can be preattached to the outlet of the mixture apparatus, allowing excess gas to be discharged therethrough and then atmospheric air to be drawn into the mixture apparatus through the filter for creating a therapeutic gas mixture.

Disclosed are methods, materials and devices for approximation of blood volume in a fluid, such as in a biological fluid collected during a surgical procedure. The method and devices include the use of a RBC flocculant, such as polyDADMAC, and an approximate blood hematocrit for the type of animal, as well as a calculated RBC packing ratio corresponding to the collection device being used. Also provided is a Blood Indicator Panel (BIP), comprising a series of markings calculated from an observed red blood settlement volume, the average animal type hematocrit, and a calculated RBC packing ratio “η” value for the collection device. Pediatric (about 200 ml or 250 ml size container), adult human (about 1,000 ml-1,500 ml) and veterinary (about 500 ml-2,500 ml) collection containers are also disclosed, that include a RBC flocculant, for use in approximating blood volume in a fluid.

A dental instrument is configured to reduce user discomfort and increase control over the surgical edge of the instrument. The invention further discloses a dental instrument having a replaceable blade.

It is disclosed a System for sampling tissue from an ear of an animal including: —a male component (2) including a detachable sample collecting part (2b), comprising a cavity (2c) for collecting the sample and a cutting edge (2a) at an aperture of the cavity (2c) for cutting the sample from the animal ear; and —a tissue sample container (3) including a container component (30) for receiving the sample collecting part (2b) and the tissue sampled, the container component (30) having an opening (30b) closed by a sealed membrane or a cover (30d).

The tissue sample container (3) includes —a ring (31) comprising a peripheral flange (31a), a protrusion (31b) and radial portions (31c), the radial portions (31c) supporting the protrusion (31b) in the middle of the peripheral flange (31a) of the ring (31); —a moulded portion (32) around the peripheral edge (31a) of the ring (31) and the container component (30), to embed the ring (31) and the container component (30) above the sealed membrane or cover (30d), preventing detachment thereof, wherein the protrusion (31b) projects from the middle of the ring (31) in a direction opposite with respect to the container component (30) and wherein a length of the protrusion (31b) is equal to or minor than a depth of the cavity (2c) of the sample collecting part (2b) to enter entirely the cavity (2c) through the aperture thereof so as the cutting edge (2a) contacts the radial portions (31c) for cutting them at a predetermined portion (31cc) during use, when the sample collecting part (2b) is moved in a same axis along which the protrusion (31b) is arranged.