In some embodiments, the presently disclosed subject matter provides a method of delivering a bioactive composition to ceca of a bird. In some embodiments, the method comprises (a) providing a bioactive composition; (b) delivering a treatment effective amount of the bioactive composition to a cloaca of the bird; and (c) providing stimulation to a vent of the bird; whereby delivery of the bioactive composition to the ceca of the bird is accomplished.

In some embodiments, the presently disclosed subject matter provides a method of delivering a bioactive composition to ceca of a bird. In some embodiments, the method comprises (a) providing a bioactive composition; (b) delivering a treatment effective amount of the bioactive composition to a cloaca of the bird; and (c) providing stimulation to a vent of the bird; whereby delivery of the bioactive composition to the ceca of the bird is accomplished.

A hypodermic interface assembly is disclosed. The hypodermic interface assembly includes a hub, a cannula, and a cannula carrier. The cannula carrier is non-removably-connected to the cannula. The cannula carrier is controllably separable from the hub.

For fixedly implanting a device for material or signal delivery or acquisition or a part of such a device in a human or animal body, an opening is provided in hard tissue of the body, the opening reaching through a hard tissue layer, e.g. through a cortical bone layer into cancellous bone underneath. The device includes a plug portion and/or a cover portion which includes a ring of a material having thermoplastic properties extending around the plug portion or on a tissue facing surface of the cover portion. The opening provided in the hard tissue has a cross section at least in the area of its mouth that is adapted to the plug or cover portion such that the plug portion can be introduced through the mouth of the opening or the cover portion can be positioned over the mouth of the opening such that the ring extends around the opening, along its wall and/or on the hard tissue surface around its mouth.

For fixedly implanting a device for material or signal delivery or acquisition or a part of such a device in a human or animal body, an opening is provided in hard tissue of the body, the opening reaching through a hard tissue layer, e.g. through a cortical bone layer into cancellous bone underneath. The device includes a plug portion and/or a cover portion which includes a ring of a material having thermoplastic properties extending around the plug portion or on a tissue facing surface of the cover portion. The opening provided in the hard tissue has a cross section at least in the area of its mouth that is adapted to the plug or cover portion such that the plug portion can be introduced through the mouth of the opening or the cover portion can be positioned over the mouth of the opening such that the ring extends around the opening, along its wall and/or on the hard tissue surface around its mouth.

An arrangement for delivery of a substance to an animal and a method of protection of a winged capsule. The arrangement may include a winged capsule including a capsule and wings, the capsule being adapted to deliver the substance to the animal, and the wings affixed to the capsule and operable to fold for insertion into the animal and to expand after insertion. The arrangement may include a wing protector including a slot sized and configured to receive at least a portion of each of the wings and removably attach the winged capsule to the wing protector. The method may include removably attaching the winged capsule to the wing protector to form a protected winged capsule; inserting a plurality of the protected winged capsule into a bag; removing one of the protected winged capsule from the bag; and removing the wing protector from the protected winged capsule.

An arrangement for delivery of a substance to an animal and a method of protection of a winged capsule. The arrangement may include a winged capsule including a capsule and wings, the capsule being adapted to deliver the substance to the animal, and the wings affixed to the capsule and operable to fold for insertion into the animal and to expand after insertion. The arrangement may include a wing protector including a slot sized and configured to receive at least a portion of each of the wings and removably attach the winged capsule to the wing protector. The method may include removably attaching the winged capsule to the wing protector to form a protected winged capsule; inserting a plurality of the protected winged capsule into a bag; removing one of the protected winged capsule from the bag; and removing the wing protector from the protected winged capsule.

An applicator for external action formulations is shown, and in particular a disposable applicator for formulations combatting ectoparasites of humans and animals is shown, including at least one formulation container (2) provided with a dispensing outlet (21). In order to protect the patient against possible injury during the application of the formulation, the applicator (1) also includes a plastic cap (3) having a form of a convex solid shell provided with a domed tip end (31) with a dispensing opening (32) which in the working mode of the applicator (1w) surrounds the dispensing outlet (21) of the formulation container (2), and connecting means (23, 34) which in the working mode of the applicator (1w) secure the cap (3) on the formulation container (2).

An applicator for external action formulations is shown, and in particular a disposable applicator for formulations combatting ectoparasites of humans and animals is shown, including at least one formulation container (2) provided with a dispensing outlet (21). In order to protect the patient against possible injury during the application of the formulation, the applicator (1) also includes a plastic cap (3) having a form of a convex solid shell provided with a domed tip end (31) with a dispensing opening (32) which in the working mode of the applicator (1w) surrounds the dispensing outlet (21) of the formulation container (2), and connecting means (23, 34) which in the working mode of the applicator (1w) secure the cap (3) on the formulation container (2).

A process of making a composition of matter with emollient properties. The composition takes the physical form of an oil base homogenized into water, making it suitable for dispensation in large quantities with a spray bottle or a continuous flow. Preparation begins with refinement of MCT coconut oil to remove lauric acid. The coconut oil is mixed with arnica oil, castor oil, and CBD oil to form the oil base. Ideal proportions for the oil base are approximately 1:4:1:4 arnica:castor:CBD:coconut. The oil base is then heated and homogenized into alkaline water by blending. Ideal parameters are approximately 11.5 pH water, a ratio of approximately 7:93 oil:water, and ten minutes of blending. Suitable variations on the ideal parameters are disclosed below.