A biodegradable lens-shaped patch useful for healing and treatment of ocular conditions is disclosed. The patch is formed from a biodegradable carrier which carries amniotic extract and/or placental extract. The lens-shaped patch may be shaped in the form of a conventional contact lens and it is applied to a corneal surface to enhance healing thereof. After a certain period of time, the patch dissolves on its own and it need not be removed from the eye by a clinician. In an embodiment, the patch includes a clear central section that may be refractory, and a biodegradable peripheral section.

An applicator for ophthalmic solutions in single-dose containers includes a structure, an oval rim, a container attachment portion, a hollow and flat support base, and additional features. The structure with open spaces is for inserting, removing, and pressing the single-dose container and allowing the label and the contents of the container to be viewed. The oval rim has a concave upper lip and a concave lower lip to facilitate the positioning of the applicator at an angle between 30 and 60° with respect to a horizontal plane. The features of the applicator enable the device to be used easily, ergonomically, comfortably, and ensure a safe use of the single-dose container in applications after the first use.

An eye treatment device includes the following: a goggle frame, having at least one cavity, configured to surround and be spaced from an eye; a corrective lens along a face of the goggle frame; and an inlet formed in an upper portion of the goggle frame, the inlet fluidly communicating the cavity to an external environment; further including: a sealing material along a perimeter of the goggle frame for forming a hermetical seal against skin around a socket of the eye, wherein the sealing material is a portion of a suction cup; and further including a tapered stopper for fluidly sealing the inlet, wherein the corrective lens is made from gas permeable material.

A laser system calibration method and system are provided. In some methods, a calibration plate may be used to calibrate a video camera of the laser system. The video camera pixel locations may be mapped to the physical space. A xy-scan device of the laser system may be calibrated by defining control parameters for actuating components of the xy-scan device to scan a beam to a series of locations. Optionally, the beam may be scanned to a series of locations on a fluorescent plate. The video camera may be used to capture reflected light from the fluorescent plate. The xy-scan device may then be calibrated by mapping the xy-scan device control parameters to physical locations. A desired z-depth focus may be determined by defining control parameters for focusing a beam to different depths. The video camera or a confocal detector may be used to detect the scanned depths.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

A collagen cross-linking system for treating a tissue of a patient, the system including: a catheter having a flexible shaft and a conforming member, the flexible shaft having distal and proximal ends, a shaft body extending between the distal end and the proximal end, the shaft body defining a lumen, the conforming member being fixed to the catheter shaft near the distal end, the conforming member comprising a membrane defining a cavity in fluid communication with the lumen; a fluid source coupled to the proximal end of the catheter, the flexible shaft of the catheter being configured so that a flow of photosensitizing fluid provided by the fluid source flows through the membrane of the conforming member; and a light source coupled to the proximal end of the catheter, the catheter being configured so that photo-activating light generated by the light source passes through the membrane of the conforming member.

A method of performing laser surgery in a patient's eye includes generating a light beam, deflecting the light beam using a scanner to form an enclosed treatment pattern that is configured to form an enclosed capsulorhexis incision that includes a registration feature, and delivering the enclosed treatment pattern to target tissue in the patient's eye to form in an anterior lens capsule of the patient's eye the enclosed capsulorhexis incision that includes the registration feature. The registration feature is configured so that an edge of the target tissue formed by the enclosed capsulorhexis incision mates with an intraocular lens registration feature on an intraocular lens so as to rotationally register the intraocular lens relative to the registration feature.

A liquid formulation of an ophthalmic drug in a pharmaceutical package, for example a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer.

Various embodiments of the present disclosure provide systems and methods for managing medication usage. The method performed by a server system includes receiving a plurality of user inputs from a medication monitoring application available in a user device associated with a user. The plurality of user inputs includes an initial medication volume present in a medication dispenser associated with the user, a medication regimen, and dosage schedules of the medication. The method includes tracking a medication usage of the user through the medication dispenser based at least on the plurality of user inputs. The method further includes transmitting an alert message to the user and at least one authorized user of the medication monitoring application to whom the user authorized to share information related to the medication usage based at least on detection of a plurality of medication dispensing events.