A cardiac valve delivery system includes a lead configured to be inserted through a venous system to a heart, the lead having a distal end with a myocardial attachment apparatus, and a transcatheter prosthesis element configured to be delivered along the lead. The transcatheter prosthesis is configured with an anchoring element located on the outside rim of the prosthesis, configured to fix the transcatheter prosthesis in place along the lead. The prosthesis is also movable along the lead and steerable towards the appropriate angulation with the lead.

The present invention relates to a stent for splinting a nasal passage. The stent consists of a braided tubular support body which, in unloaded state, has a diameter of at least 4 mm and a length in the range of 25 to 120 mm and particularly of 25 to 100 mm. The stent may have a widened section at the proximal end for splinting of the nasal alar. It may alternatively or in combination have a fixation section at the proximal end of the stent for fixation of the stent in a nasal passage of a user. When fixed the fixation section protrudes from the nostril of the user and can be fixed outside of the nose.

The present invention relates to an intraocular lens comprising: a primary lens (1000) having a first focal length, a first surface, and a second surface; a secondary lens (2000) having at least two focal lengths, a first surface (2100), and a second surface (2200), wherein the second surface (2200) of the secondary lens (2000) conforms to the first surface of the primary lens (1000), while the secondary lens (2000) is attached to the primary lens (1000) by peelable adhesive forces over substantially its second surface (2200).

Transluminally implantable cardiac valves configured for use in cardiac valve replacement and/or cardiac valve exclusion that are capable of percutaneous delivery on low-profile catheters having 15 French size or less. The implantable cardiac valves are fabricated of from a unitary metal material to form a lattice frame support having a main body portion and valve leaflet portion, and a plurality of elongate biasing arm members. A polymer coating or covering is disposed on the valve leaflet portion and the elongate biasing arm members and subtends space between adjacent pairs of elongate biasing arm members to form valve leaflet portions in which the elongate biasing arms and the polymer coating operate to share a mechanical load thereupon.

A tibial trial insert system includes a bearing component having a superior articulating surface for articulation with a distal femoral surface, a plate component having an inferior fixation surface for fixation to a proximal tibia, and an adjustment arrangement for adjusting a proximal/distal spacing between the bearing component and the plate component. The adjustment arrangement includes an adjustment device having a superior connector element that engages an inferior surface of the bearing component, an inferior base element adapted to be placed upon a superior surface of the plate component, and a telescopic mechanism coupled to the connector element and the base element. The telescopic mechanism can adjust a thickness of the adjustment device. At least one shim is insertable between the superior surface of the plate component and an inferior surface of the base element for adjusting a height level of the adjustment device relative to the plate component.

An IOL system includes a capsular ring having a concave exterior surface extending around its circumference that is configured, upon insertion into a capsular bag of a patient's eye, to engage an equatorial region of the capsular bag. The concave exterior surface extends between an anterior surface and a posterior surface of the capsular ring. A first one or more flaps are arranged on the anterior surface such that at least a portion of each of the first one or more flaps, upon insertion into the capsular bag of a patient's eye, engages an anterior portion of the capsular bag. Similarly, a second one or more flaps are arranged on the posterior surface such that at least a portion of each of the second one or more flaps, upon insertion into a capsular bag of a patient's eye, engages a posterior portion of the capsular bag.

Arthroplasty implants replace an articulating surface of a bone joint such as bone joints of the foot, and is characterized by a three-component device comprising a bone screw, a button, and a cap. The button incorporates knurling on its distal end to fixate onto bone, a center hole, a spherical pocket to mate with the bone screw for stabilization, and a proximal retention structure to mate with the cap. The bone screw incorporates distal bone (cortical) threads or threading, a spherical head, and a drive structure used to insert the bone screw through the hole of the button and into the bone (e.g. a distal segment of the first metatarsal). The cap incorporates a distal mating structure that retains the cap onto the button, a proximal smooth spherical head that mates with the distal surface of the bone (e.g. a phalange bone), and a tang that prevents rotation after implantation.

Devices for encapsulating biological entities (e.g., cells) where the encapsulating devices are implanted into a tissue bed of a patient to provide biological therapy are disclosed. The encapsulation device includes a inactive region (e.g., weld area) located around the periphery of the device. The inactive region is non-porous and prevents cellular ingrowth and/or vascularization therein. An anchor region containing an ingrowth layer and a bonding layer may be attached or otherwise affixed to the inactive region. The open microstructure of the ingrowth layer permits for rapid cellular and/or vascular ingrowth to stabilize the encapsulation device within the host tissue. In some embodiments, inactive regions can be formed in location(s) on the cell retaining region of the encapsulation device.

An implant configured to control travel of a leaflet of a heart valve, the implant comprising a first implant member, the first implant member having a first implant member first fastener, a first implant member second fastener, a tether connecting the first implant member first fastener and the first implant member second fastener and a first implant member connector slidably disposed on the tether; a second implant member, the second implant member having a second implant member connector and a second implant member anchor; wherein the first implant member connector and the second implant member connector are magnetically couplable, and wherein at least one of the first implant member connector and the second implant member connector comprises a permanent magnet.