Methods and systems for treating skin, such as stretch marks through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a shallow tissue region, such as a region comprising an epidermis, a dermis or a deep dermis. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth with a conformal selective deposition of ultrasound energy without damaging an intervening tissue. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.

Embodiments of the present disclosure are directed to methods of inducing therapeutic adipose tissue inflammation using high frequency pressure waves (e.g. high frequency shockwaves) wherein the inflammation results in a reduction in the volume of subcutaneous adipose tissue. Embodiments include applying electrohydraulic generated shockwaves at a rate of between 10 Hz and 100 Hz to reduce the appearance of cellulite or the volume of subcutaneous fat in a treatment area.

Methods and systems for treating skin, such as stretch marks through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a shallow tissue region, such as a region comprising an epidermis, a dermis or a deep dermis. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth with a conformal selective deposition of ultrasound energy without damaging an intervening tissue. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.

Provided in the present invention is a handpiece (300) for a treatment device with improved stability and hygiene function by being configured so as to freely adjust the angle of a vacuum cap depending on a treatment site and to attach/detach the vacuum cap to/from the handpiece (300). The handpiece (300) capable of attaching/detaching a vacuum cap and adjusting an angle of the vacuum cap comprises: a vacuum cap (310) having an open lower surface and a hollow part formed therein; a body part (410) configured to attach/detach the vacuum cap (310) thereto/therefrom; a vacuum device (350) for providing a reference negative pressure to the vacuum cap so that a target site of the skin can be adhered toward the hollow part of the vacuum cap; a reference negative pressure variable device (360) for varying the reference negative pressure in a pulse form under the condition in which the hollow part of the vacuum cap (310) maintains the negative pressure; RF electrodes (320, 321) configured to be exposed to the inside wall of the vacuum cap (310) so that, when the target site of the skin has been adhered toward the hollow part of the vacuum cap (310), the skin adhered toward the hollow part comes into contact with the inside of the hollow part of the vacuum cap (310); and a control unit (380) for controlling driving of the vacuum device (350), the reference negative pressure variable device (360), and the RF electrodes (320, 321). The driving of the reference negative pressure variable device (360) and the RF electrodes (320, 321) for treating the target site of the skin is controlled so as to select any one of single driving, simultaneous driving, and alternating driving. The attachment/detachment of the vacuum cap (310) to/from the body part (410) is made by simultaneous coupling or simultaneous separation of a vacuum cap connection unit (430) that consists of a vacuum tube coupler (432) configured at an end of the body part (410), power supply connectors (433, 434), and a clip (435).

Disclosed are methods and devices suitable for transdermally killing adipocytes in a subcutaneous fat layer of a human subject.

A method and a system for skin treatment are presented. A muscle stimulating element is configured to provide muscle stimulation to a muscle layer located below the skin tissue, at least one pressure application element is configured to apply pressure on the skin tissue, a handheld applicator is configured to be placed in vicinity of the skin tissue to deliver said muscle stimulation from said muscle stimulating element and said pressure from said at least one pressure application element to one or more muscles in the muscle layer located below the skin tissue; and a control board is configured and operable to activate the muscle stimulating element and the at least one pressure application element according to one or more activation patterns adapted to provide one or more treatments to the skin tissue.

Embodiments of the present disclosure are directed to methods of inducing therapeutic adipose tissue inflammation using high frequency pressure waves (e.g. high frequency shockwaves) wherein the inflammation results in a reduction in the volume of subcutaneous adipose tissue. Embodiments include applying electrohydraulic generated shockwaves at a rate of between 10 Hz and 1000 Hz to reduce the appearance of cellulite or the volume of subcutaneous fat in a treatment area.

A method and a system for treating skin tissue are provided. At least one heat generating element is configured to modify temperature of the skin tissue, a muscle stimulating element is configured to provide muscle stimulation to a muscle layer located below the skin tissue, a handheld applicator is configured to be placed in vicinity of the skin tissue to deliver said temperature modification from said at least one heat generating element to the skin tissue and said muscle stimulation from said muscle stimulating element to the muscle layer located below the skin tissue; and a control board configured and operable to activate the at least one heat generating element and the muscle stimulating element according to respective activation patterns; thereby providing one or more treatments to the skin tissue.

A system and method for skin tightening are presented. A muscle stimulating element is configured to provide muscle stimulation to a muscle layer located below the skin tissue, a handheld applicator is configured to be placed in vicinity of the skin tissue to deliver said muscle stimulation from said muscle stimulating element to the muscle layer located below the skin tissue; and a control board is configured and operable to activate the muscle stimulating element according to one or more activation patterns adapted to provide one or more treatments to the skin tissue, the one or more treatments comprising skin tightening.

A method and system for treating skin tissue are presented. A muscle stimulating element is configured to provide muscle stimulation to a muscle layer located below the skin tissue, a handheld applicator configured to be placed in vicinity of the skin tissue to deliver said muscle stimulation from said muscle stimulating element to the muscle layer located below the skin tissue, one or more sensors configured to provide measurements indicative of the muscle stimulation; and a control board configured and operable to activate the handheld applicator according to respective activation patterns; thereby providing one or more treatments to the skin tissue.