The invention provides compositions and methods for the convenient compounding of pharmaceuticals. Single and multiple unit of use kits are provided which contain all the necessary components required for preparing a compounded pharmaceutical. The kits of the invention include a first container having a first active agent and a second container having at least one second inactive agent. The kits of the invention are also useful for compounding veterinary pharmaceuticals.

Disclosed herein are methods for preparing and/or dispensing lyospheres of pharmaceutical compositions of biologics (e.g., vaccines, therapeutic proteins such as monoclonal antibodies) or small molecules (e.g., chemical compounds). Also described are assemblies and systems for preparing and/or dispensing the lyospheres.

Disclosed herein are methods for preparing and/or dispensing lyospheres of pharmaceutical compositions of biologics (e.g., vaccines, therapeutic proteins such as monoclonal antibodies) or small molecules (e.g., chemical compounds). Also described are assemblies and systems for preparing and/or dispensing the lyospheres.

Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a backpack for management of tubing to couple the cartridge to a receiving container. A disposable waste container is contained by the cartridge and the backpack. A syringe holder is provided for use of a syringe as a receiving container to receive a compounded medication.

A method includes micro-machining a cavity within a substrate, filling the cavity with a medication, forming a sealing layer over the cavity, micro-machining a cantilevered beam from a layer of material, the cantilevered beam comprising a tip for puncturing the sealing layer, and attaching the cantilevered beam to the substrate such that moving the cantilevered beam toward the substrate enables the tip to puncture the sealing layer. A computer program product corresponding to the method is also disclosed. An apparatus includes a substrate having a cavity micro-machined therein, a sealing layer formed over the cavity, a medication disposed within the cavity, a cantilevered beam micro-machined from a layer of material, the cantilevered beam comprising a tip for puncturing the sealing layer, and the cantilevered beam attached to the substrate and disposed to enable the tip to puncture the sealing layer when the cantilevered beam is moved towards the substrate.

A method includes micro-machining a cavity within a substrate, filling the cavity with a medication, forming a sealing layer over the cavity, micro-machining a cantilevered beam from a layer of material, the cantilevered beam comprising a tip for puncturing the sealing layer, and attaching the cantilevered beam to the substrate such that moving the cantilevered beam toward the substrate enables the tip to puncture the sealing layer. A computer program product corresponding to the method is also disclosed. An apparatus includes a substrate having a cavity micro-machined therein, a sealing layer formed over the cavity, a medication disposed within the cavity, a cantilevered beam micro-machined from a layer of material, the cantilevered beam comprising a tip for puncturing the sealing layer, and the cantilevered beam attached to the substrate and disposed to enable the tip to puncture the sealing layer when the cantilevered beam is moved towards the substrate.

The present application provides a co-infusion apparatus and a co-infusion method which can photograph an image suitable for inspecting whether or not a co-infusion process in the co-infusion apparatus is properly carried out.

A vial puck configured for attachment to a vial containing a drug is provided. The vial puck includes various features for facilitating uniform control of vials of various sizes in an automatic compounder system. The vial puck features may include a vial recess for receiving a vial of a particular size and securing the vial within the vial recess. The features may also include a cylindrical central portion, perpendicular extensions that extend from a top of the cylindrical central portion, a gear extending from the cylindrical central portion, and a sealing member disposed in the cylindrical central portion. The vial puck may include a cylindrical protrusion configured to press against a septum of the vial to form a seal between the vial puck and the vial. The sealing member may be configured to receive a needle of the compounder system therethrough to allow access to the vial.

Systems and methods for preventing a container from being replenished with the wrong medicine are described. This is achieved by the following process: first, a user places a container on a placement unit and reads a symbol attached to a bottle. Then, a determination is made so as to whether the medicine in the bottle is the correct medicine. If the medicine is incorrect, a message indicating the medicine is incorrect is displayed. If the medicine is correct, a camera records video of the medicine replenishment operation. Once the medicine replenishment is completed, a photographed image of the medicine inside the container and an image of the correct medicine for replenishing the container are displayed. Then, the user views these images and confirms whether the medicine used to replenish the container was correct. If this confirmation is not completed, the medicine dispensing device will not dispense medicine from the container.

Systems and methods for preventing a container from being replenished with the wrong medicine are described. This is achieved by the following process: first, a user places a container on a placement unit and reads a symbol attached to a bottle. Then, a determination is made so as to whether the medicine in the bottle is the correct medicine. If the medicine is incorrect, a message indicating the medicine is incorrect is displayed. If the medicine is correct, a camera records video of the medicine replenishment operation. Once the medicine replenishment is completed, a photographed image of the medicine inside the container and an image of the correct medicine for replenishing the container are displayed. Then, the user views these images and confirms whether the medicine used to replenish the container was correct. If this confirmation is not completed, the medicine dispensing device will not dispense medicine from the container.