Limit size lipid nanoparticles, methods for using the lipid nanoparticles, and methods and systems for making limit size lipid nanoparticles.

Limit size lipid nanoparticles, methods for using the lipid nanoparticles, and methods and systems for making limit size lipid nanoparticles.

The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.

An exemplary compounding system and method can include a transfer set that includes a manifold for assisting in transferring a plurality of ingredients from supply container(s) to a final container. The manifold can include a first channel in fluid communication with at least one primary ingredient, and a second channel in fluid communication with a plurality of secondary ingredients. The first channel and second channel can be in fluid isolation from each other such that the at least one primary ingredient does not mix with the plurality of secondary ingredients within the manifold. The transfer set can include a plurality of inlet lines in fluid communication with the manifold and two outlet lines configured for connection to two separate pumps and eventually being in fluid communication with the final container.

A method of forming bundles of glass articles is provided. The method includes transporting individual glass articles to an insert building station using a conveying system. The glass articles are individually located within article receiving slots of a layer separation insert using the conveying system. Each slot of the layer separation insert receives a single glass article forming a glass article layer of side-by-side glass articles. Multiple glass article layers including layer separation inserts are stacked using the conveying system forming a bundle. The layer separation inserts provide a barrier between adjacent glass articles of each of the glass article layers to inhibit glass-to-glass contact.

A method of forming bundles of glass articles is provided. The method includes transporting individual glass articles to an insert building station using a conveying system. The glass articles are individually located within article receiving slots of a layer separation insert using the conveying system. Each slot of the layer separation insert receives a single glass article forming a glass article layer of side-by-side glass articles. Multiple glass article layers including layer separation inserts are stacked using the conveying system forming a bundle. The layer separation inserts provide a barrier between adjacent glass articles of each of the glass article layers to inhibit glass-to-glass contact.

A drug list display method includes: obtaining a first image of drugs captured from one side of the drugs; clipping from the first image, areas where the respective drugs are displayed to obtain first clipped images; displaying the first clipped images in a list form in a certain order in a first area on a display in such a manner that one or more of the first clipped images may be designated; determining correct drugs for first clipped images designated by a user; and displaying information on the correct drugs determined for the respective first clipped images in a second area on the display different from the first area, wherein the first clipped images and the corresponding information on the correct drugs are displayed in association with each other.

Devices and methods for mixing and preparing therapeutic pellets are described. In one aspect, the present disclosure may include a medical device for mixing and preparing pharmaceuticals. The medical device may include a body sized and shaped to be supported by a human hand. The body may be elastically flexible between a relaxed shape and a flexed shape. In the relaxed shape, the body may form a basin and may be shaped and sized to receive a vessel for mixing or forming the therapeutic pellets. In the flexed shape, the bowl may be configured for controlled pouring of the therapeutic pellets.

Devices and methods for mixing and preparing therapeutic pellets are described. In one aspect, the present disclosure may include a medical device for mixing and preparing pharmaceuticals. The medical device may include a body sized and shaped to be supported by a human hand. The body may be elastically flexible between a relaxed shape and a flexed shape. In the relaxed shape, the body may form a basin and may be shaped and sized to receive a vessel for mixing or forming the therapeutic pellets. In the flexed shape, the bowl may be configured for controlled pouring of the therapeutic pellets.

A method for the preparation of pharmaceutical products is provided that utilizes a machine having a containing liner, a dosing chamber for preparing at least one pharmaceutical product accommodated within the containing liner, and a pneumatic ventilation device for feeding two air flows through the dosing chamber and through the containing liner, respectively. Operation of the pneumatic ventilation device is selectively controlled so that the containing liner has inside a pressure lower than a pressure existing within the dosing chamber and than a pressure existing in the environment outside the containing liner itself.