Compositions and methods for treating tar-responsive dermatological disorders are described. In particular, an anhydrous tar composition including a liquid wax and a therapeutically effective amount of tar in an anhydrous solvent, the composition being in liquid form at room temperature is described. The anhydrous tar composition can be topically applied to skin of a subject for treatment of tar-responsive dermatological disorders, such as psoriasis, eczema, atopic dermatitis, seborrheic dermatitis and pruritus.

The present disclosure generally relates to terpene-based compositions for applications in the pharmaceutical and recreational fields. In some embodiments, the compositions are enriched compositions or non-naturally occurring compositions which contain defined concentrations of one or more cannabis-derived chemical compounds, such as terpenes and cannabinoids that have a distinctive characteristic that mimics that of a cannabis plant matter or a product thereof. Also provided in some embodiments of the disclosure are methods for the preparation of the compositions, as well as methods for use thereof.

A composition for sebum control and pore reduction, and its use for controlling sebum and reducing pore of skin are disclosed. The external-use skin preparation composition contains, as an active ingredient, extracts of one or more medicinal herbs selected from the group consisting of Cimicifugae rhizoma, Solani nigri herba, Glycyrrhiza uralensis, Clematis mandshurica, Acanthopanax senticosus, Inulae radix and Dioscorea japonica, and thus it not only can control the production of sebum and alleviate skin troubles, but also provide antioxidant effects, prevent pore enlargement, or prevent occurrence of skin irritation.

Methods of use and compositions useful for moisturizing skin, conditioning skin, reducing lines and wrinkles, evening skin tone, lightening skin tone, increasing skin radiance, elasticity, skin barrier function, and/or skin firmness, reducing photodamage, reducing sagging skin, increasing anti-oxidant capacity in skin, MMP-1, MMP-3, MMP-9, pro-inflammatory cytokines (e.g., lipoxygenase, IL-6, Il-8, TNF-α, or VEGF), and/or elastase expression in skin, and/or increasing collagen expression in skin, elastin expression in skin, laminin expression in skin, and/or fibronectin expression in skin are disclosed herein. The composition includes a combination of one or more of Rosmarinus officianalis leaf extract, Caulerpa lentillifera extract, Morus alba fruit extract, and Porphyridium cruentum extract.

A xanthine oxidase inhibitor and a uric acid-producing inhibitor, each containing an extract from at least one member selected from the group consisting of Zanthoxylum bungeanum, Sorghum nervosum, Cuminum cyminum, Rosa centifolia, Pimenta officinalis, Origanum majorana, Psidium guajava, Pimpinella anisum, Olea europaea, Illicium verum, Canavalia gladiata, Hyssopus officinalis, Ribes nigrum, Vaccinium myrtillus, Artemisia princeps and Haematoxylon campechianum L.

A xanthine oxidase inhibitor and a uric acid-producing inhibitor, each containing an extract from at least one member selected from the group consisting of Zanthoxylum bungeanum, Sorghum nervosum, Cuminum cyminum, Rosa centifolia, Pimenta officinalis, Origanum majorana, Psidium guajava, Pimpinella anisum, Olea europaea, Illicium verum, Canavalia gladiata, Hyssopus officinalis, Ribes nigrum, Vaccinium myrtillus, Artemisia princeps and Haematoxylon campechianum L.

A xanthine oxidase inhibitor and a uric acid-producing inhibitor, each containing an extract from at least one member selected from the group consisting of Zanthoxylum bungeanum, Sorghum nervosum, Cuminum cyminum, Rosa centifolia, Pimenta officinalis, Origanum majorana, Psidium guajava, Pimpinella anisum, Olea europaea, Illicium verum, Canavalia gladiata, Hyssopus officinalis, Ribes nigrum, Vaccinium myrtillus, Artemisia princeps and Haematoxylon campechianum L.

The present invention is drawn to personal care products containing combinations of plant-based glyceride butters and plant-based glyceride oils, and their use in retaining moisture and natural flora in the skin, such as the hands and vaginal lips.

The present invention provides a novel substance that promotes expression of filaggrin gene involved in improvement of the moisture retention function of skin. The inventors of the present invention found that expression of filaggrin gene fluctuates rhythmically over a roughly 24 hour cycle, screened candidate substances based on the time at which expression reaches a maximum following addition of the candidate substance, and identified zanthoxylum extract, 3-(1′-piperidine)propionic acid, geranium oil, cypress oil, rose oil, galvanum oil, pepper oil, basil oil, methyl-o-toluate, methyl anthranilate and dimethyl anthranilate as filaggrin gene expression promoting agents.

A method of obtaining a rutin-rich extract from a plant and a rutin-rich extract of Uncaria elliptica thus obtained.