The invention relates to a method of separation by fractionalization of the antioxidant active ingredients of Rosemary plant, which are the diterpenes Carnosic acid and Camosol and the phenolic acid Rosmarinic Acid, through column chromatography method. The production process involves the passage of rosemary extract, which is obtained in/with a proper solvent, through a column packed with a suitable packing material, the separation of the part rich in carnosic acid and carnosol, and the obtainment of a deodorized product in powder form after drying. During the process, another extract containing rosmarinic acid with high antioxidant activity is also obtained. The invention thus allows the use of an extract rich in carnosic acid and carnosol and another extract containing rosmarinic acid—which are obtained at once with no need for additional processes like acidification, precipitation, membrane filtration or deodorization—in food, pharmaceutical and cosmetic sector applications.

A composition for treating respiratory diseases and strengthening the immune system is provided including a synergic mixture of a) oil extracted from seeds of the plant Nigella sativa diluted in propylene glycol with b) an alcoholic extract with ethanol obtained from aerial parts of the plant Asclepias curassavica. The composition is prepared by (a) extracting seed oil from the Nigella sativa plant, adding the extracted seed oil to propylene glycol; (b) macerating aerial parts of Asclepias curassavica plants in ethanol with a resting time if subjected to a water bath or another resting time without the water bath, straining and filtering; c) mixing a volume of the alcoholic extract of Asclepias curassavica with a volume of oil extracted from the seeds of the Nigella sativa plant diluted in propylene glycol; d) shaking and letting it rest.

Provided is a pharmaceutical composition for preventing, alleviating or treating coronavirus infection, containing an Elaeocarpus sylvestris leaf extract as an active ingredient, and a food composition for preventing or alleviating coronavirus infection. Since the Elaeocarpus sylvestris leaf extract exhibits excellent anti-viral activity against coronavirus which is a virus causing a respiratory disease, a digestive disease, a liver disease or a brain disease in a mammal, particularly, the corona-19 virus, it may be effectively used in medicines and food for preventing, alleviating or treating a disease caused by coronavirus infection.

A Camellia extract obtained by extracting by ultrasound a powder of Camellia japonica flowers, the powder being impregnated with a fatty substance or a mixture of fatty substances, with a hydroalcoholic solvent, and a cosmetic composition including such an extract having in particular a soothing effect for the skin. Also, a non-therapeutic use thereof for soothing the skin.

The invention relates to an extract of Ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of Ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The disclosure also provides a method of improving bioactivity of withanolide glycosides even at lower doses, by the administration of an enteric coated formulation of extract of Ashwagandha to humans. The enteric coating protects the composition from hydrolysis in the acidic environment of the stomach to release the withanolide glycoside in neutral/alkaline pH in gastrointestinal tract (GIT) thus enhancing the absorption. Further the process of preparation of the extract of Ashwagandha enriched with withanolide glycosides and saponins are disclosed along with various formulations.

Composition for modulation/regulation ncRNAs, Lymphocytes, Neutrophils, Inflammasomes and p53 for prevention, treatment and management of immune dysregulation, inflammation dysregulation and energy dysregulation, caused by respiratory viruses (COVID19, Influenza etc), or leading to Acute Respiratory Distress Syndrome (ARDS), Sepsis and Long Covid, immune senescence.

The present invention relates to a method for preparation of soybean leaves having a high content of an isoflavone derivative in a dark condition and soybean leaves having a high content of an isoflavone derivative prepared thereby. Specifically, treatment of a soybean plant 20 days to 60 days after seeding with a predetermined concentration of ethylene in a dark condition was found to accumulate higher concentrations of isoflavone derivatives in soybean leaves than treatment with ethephon in a light condition, which requires a high level of energy. Therefore, when used, the method of the present invention can economically and quickly prepare soybean leaves having a very high content of isoflavones, and the soybean leaves having a high content of isoflavone derivatives, an extract of the soybean leaves, and a fraction of the extract can be advantageously used as a food and medicine material against diseases caused by estrogen unbalance and deficient antioxidant activity.

The present patent application relates to a lyophilisation process of Annatto Bixa Orellana L. powder having a tocotrienol content >35% (w/w), comprising a pre-freezing step and a freeze-drying step, in which the Annatto powder resulting from the freeze-drying step (c) has a tocotrienol content >39% (w/w). The invention also relates to pharmaceutical compositions comprising lyophilised

Annatto powder obtained with the process of the invention and therapeutic uses of such compositions, in particular to support cancer therapy.

This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.

The invention relates to an extract of Moringa peregrina seeds rich in the compound 2,5-diformylfuran, more specifically an extract of the cake of said seeds, and to a process for extracting the extract. The invention also relates to cosmetic or nutricosmetic compositions comprising said extract and to the use of said compositions for improving the appearance of the skin, mucous membranes or the integuments, for relaxing, soothing and destressing the skin and for preventing and/or combating the signs of aging and/or photoaging of the skin, and for preventing age spots.