The ophthalmologic microscope has an illumination device for projecting light onto an eye to be observed and a microscope device with a camera to view the eye. The illumination device generates pulsed light. The light is pulsed at least at twice the frame rate of the camera to reduce flicker. The illumination device uses an array of micro-mirrors as spatial light modulator, and the mirrors are controlled for a balanced deflection over the frame cycles, which allows to increase the service life of the microscope.

A vision screening device for administering vision screening tests, and in particular a color vision screening test, to a patient is described herein. The vision screening device may include associated methods and systems configured to perform the operations of the vision screening tests. The device may include a first radiation source configured to generate color stimuli, a second radiation source separate from the first radiation source configured to emit near-infrared radiation, and a sensor configured to capture the near-infrared radiation emitted by the second radiation source, and reflected by an eye of a patient. The device may also be configured to cause color stimulus to be displayed to the patient, and determine measurement(s) of the eye of the patient in response to the color stimulus. The device may be further configured to analyze the measurements to generate a recommendation and/or diagnosis associated with the vision of the patient. The device may also be configured to display the recommendation and/or the measurements, along with additional screening data, to an operator conducting the vision test.

Provided herein are systems, devices and methods for monitoring the progression of, determining and/or assessing brain related conditions in a subject based on pupil light responses (PLRs) to focal central and peripheral chromatic light stimuli, in particular, by classifying the PLR based on one or more PLR parameter values, wherein the classifying allows monitoring the progression of, determining and/or assessing the brain related condition

A mobile communication device-based corneal topography system includes an illumination system, an imaging system, a topography processor, an image sensor, and a mobile communication device. The illumination system is configured to generate an illumination pattern reflected off a cornea of a subject. The imaging system is coupled to an image sensor to capture an image of the reflected illumination pattern. A topography processor is coupled to the image sensor to process the image of the reflected illumination pattern. The mobile communications device includes a display, the mobile communications device is operatively coupled to the image sensor. The mobile communications device includes a mobile communications device (MCD) processor. A housing at least partially encloses one or more of the illumination system, the imaging system, or the topography processor.

In some embodiments, a microsurgical instrument includes a trocar having a rigid, hollow shaft formed with a lumen extending from a proximal end to a distal end of the shaft. The distal end of the shaft may be shaped for tissue penetration. The instrument may further include a composite microcannula slidably engaged with the trocar in the lumen. The microcannula includes a light guide and a flexible hollow tube having an outer diameter less than an inner diameter of the lumen in the trocar. Other embodiments include placing the microcannula in the lumen of the trocar, illuminating the end of the trocar by illuminating the end of the microcannula, advancing the trocar from a selected entry point on an eye into a selected structure in the eye, and extending the illuminated end of the microcannula from the trocar into the selected structure.

Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

Methods and devices determine an eye strain indicator. In one aspect, an augmented reality (AR) device wearable by a user includes an image sensor and a processor coupled to the image sensor. The processor receives image data from the image sensor, determine that a display is within a field of view (FOV) of the AR device, determine an eye strain indicator based on the determination that the display is within the FOV of the AR device, and provide the eye strain indicator to the user.

Systems and methods are provided for measuring the mechanical properties of ocular tissue, such as the lens or corneal tissue, for diagnosis as well as treatment monitoring purposes. A laser locking feedback system is provided to achieve frequency accuracy and sensitivity that facilitates operations and diagnosis with great sensitivity and accuracy. Differential comparisons between eye tissue regions of a patient, either on the same eye or a fellow eye, can further facilitate early diagnosis and monitoring.

A hand-held sized ocular and neurological screening device, system and method, the screening device comprising an eyepiece and a hand-held housing, the housing comprising a tubular stimulus chamber defining a light stimulus channel, wherein an illumination source is configured to provide light stimulus towards an opening through the light stimulus channel and an operational chamber comprising an infrared camera positioned outside the stimulus channel and inclined towards the opening, the infrared camera is configured to capture images of the pupils and eye movements through the opening without interfering with the light stimulus and a controller configured to receive the captured images from the infrared camera. The hand-held sized device can include a clip-on fixture for fixing the device onto a table, a desktop, or any portable ophthalmic apparatus.

In some embodiments, an ophthalmic laser system may be provided that does not include a traditional laser console. Instead, the treatment device may be configured to house the treatment light source within the device handle. Additionally, in some embodiments, the handheld treatment device may include a user interface, such as dials and buttons, for adjusting various parameters of the therapeutic light. With certain embodiments, the self-contained handheld treatment device may be operated independent of an AC power source. For example, in some embodiments, the handheld treatment device may be battery powered. Additionally, the handheld treatment device may be disposable or may utilize replaceable distal tips in certain embodiments. Certain embodiments may be particularly designed for transscleral cyclophotocoagulation. Also, treatment guides are provided that may be configured to couple with a treatment device to align the device with a target tissue of the eye.