Methods are provided for coating particles characterised by the addition of a powdered excipient, typically during coating. Typically, the coating method comprises Wurster fluidized bed coating. The method provides for coating particles in a coater comprising a coating processing chamber, wherein the particles comprise an active pharmaceutical ingredient. The coated particles are preferably for use in a method of administering an active pharmaceutical ingredient or for use in a method of treating or preventing a disease or condition. The invention further provides a pharmaceutical composition comprising coated particles obtainable by the method of the invention, preferably as part of a liquid formulation for oral administration.

Dentifrice compositions comprising zinc lactate, glycine, and fluoride ion are provided for treating dental plaque biofilm.

An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.

A denture containing a henna powder or a henna extract, each of which comes from pulverized henna leaves and may include any of lawsone, tannic acid, and 2-methoxy-1,4-napthoquinone and a denture fabrication material. A denture containing at least one first antimicrobial ingredient selected from the group consisting of henna powder or a henna extract, lawsone, tannic acid, and 2-methoxy-1,4-napthoquinone, and a second antimicrobial ingredient, and optionally, a biocompatible gel and an odor neutralizer.

An example article may include a dental surface, a hydrophobic coating on the dental surface, and a restorative layer on the hydrophobic coating. An example technique may include applying, on a dental surface, a hydrophobic coating comprising an amphiphilic agent. The hydrophobic coating may provide a water contact angle of greater than or equal to about 50° on the dental surface. The example technique may include applying a restorative layer to the hydrophobic coating. An example kit may include a dental restorative composition and a hydrophobic coating composition. The hydrophobic coating composition may include an amphiphilic agent. The hydrophobic coating composition may be configured to provide a water contact angle of greater than or equal to about 50° on a dental surface.

The present invention relates to intranasally administered pharmaceutical compositions administered for use in anesthesia. Such pharmaceutical compositions comprise benzyl alcohol. The invention also relates to methods for anesthetizing the maxillary dental arch using these pharmaceutical compositions.

An oral care composition which is a liquid at or below room temperature and which forms a two-phase cloudy system at body temperature and wherein the composition comprises a water-soluble non-ionic polymer, such as HPC, having a cloud point in the composition at a temperature no higher than about 38° C., for combating (i.e. helping to prevent, inhibit and/or treat) dentinal hypersensitivity.

A composition and method for use in a dental treatment, such as root canal. The composition eliminates the need for uncomfortable and time-consuming needle injections before application of prep composition. The composition is a mixture of a lubricant, a disinfecting agent, a chelating agent and an anesthetic, preferably articaine, and may also include epinephrine. A method for preparing an area of the patient's mouth for the dental treatment, such as a root canal, is achieved by preparing the disclosed composition and administering it to the area of the patient's mouth to be treated. The composition provides simultaneous antibacterial action and numbing action with a one-step application.

A single and dual component dental composite restorative featuring anti-microbial and low Coefficient of Thermal Expansion (CTE) compounds is disclosed. The exemplary anti-microbial compound is zinc oxide. The CTE of the dental composite restorative is the same as, or substantially similar, to that of dentin. By maintaining a CTE substantially similar to that of dentin, the Margin Percolation phenomenon is minimized, which decreases the incidence of secondary caries.

The present invention relates to a kit for indirect production of composite inlays, comprising a polymerizable material for production of a dental model, a polymerizable material for production of an inlay, a polymerizable material for luting of a crosslinked and non-sand-blasted, non-silanized, non-etched, non-primed and non-roughened composite inlay, the surfaces of which have been fully polymerized, in the cavity. Also disclosed is a polymerizable material for increasing the bond strength between the polymerizable material for luting of a crosslinked non-sand-blasted, non-silanized, non-etched, non-primed and non-roughened composite inlay, the surfaces of which have been fully polymerized, in the cavity, and the hard substance of the tooth, and an acid solution for surface etching of the hard substance of the tooth. The invention further relates to methods for producing a composite inlay.