Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12Y
ENZYMES
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304/00
Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
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C12Y304/21
Serine endopeptidases (3.4.21)
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C12Y304/21034
Plasma kallikrein (3.4.21.34)
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C12Y304/21034

Modulation of prekallikrein (PKK) expression
12595485 · 2026-04-07 · ·

Disclosed herein are antisense compounds and methods for decreasing PKK mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate PKK-associated diseases, disorders, and conditions.