The present invention relates to a composition for epimerization of a non-phosphorylated hexose, comprising sugar epimerases derived from thermophiles, and a method for preparing a non-phosphorylated hexose epimer using the composition. The sugar epimerases derived from thermophiles according to the present invention can effectively catalyze an epimerization reaction of a non-phosphorylated hexose and can easily produce an epimer form of the non-phosphorylated hexose, in particular a rare sugar hexose, and thus can be usefully utilized in the pharmaceutical and food industry.

Mammalian milk oligosaccharides (MMO) are produced in plants engineered to express recombinant MMO biosynthetic pathways.

The present invention relates to primarily genetically modified microorganisms for in vivo synthesis of lacto-N-tetrose (LNT) and lacto-N-neotetrose (LNnT), and their fucosylated derivatives, and to uses of such microorganisms in methods of producing lacto-N-tetrose and lacto-N-neotetrose, and their fucosylated derivatives.

Disclosed are genetically engineered microbial cells for the production of oligosaccharides comprising a galactose-1,4-glucose moiety at their reducing end, wherein said microbial cells are able to produce said oligosaccharides in the absence of exogenously added lactose, and a method of producing said oligosaccharides using said microbial cells.

The present invention relates to a method for producing lacto-N-tetraose (LNT) and lacto-N-neotetraose (LNnT) using Corynebacterium glutamicum, and more specifically to: recombinant Corynebacterium glutamicum transformed such that, in order to increase productivity of LNT and LNnT, genes introduced from outside are expressed in Corynebacterium glutamicum, and genes inherent in Corynebacterium glutamicum are overexpressed; and a method for producing LNT and LNnT using same. Accordingly, the present invention uses Corynebacterium glutamicum so as to enable producing LNT and LNnT in a safe manner and in high concentration, high yield, high productivity, compared to when using conventional Escherichia coli.