Compositions, methods and kits are provided for treating complement related disorders in a subject with protein in combination having protein fusions of at least two of a CD46 protein, a CD55 protein and a CD59 protein or with a recombinant chimeric protein having at least two of a CD46 protein, a CD55 protein and a CD59 protein or with nucleic acids encoding these proteins. The composition negatively modulates classical and alternative complement pathways thereby treating complement related disorder such as macular degeneration, age-related macular degeneration, diabetic retinopathy, inflammatory bowel disease, thyroiditis, cryoglobulinaemia, fetal loss, organ graft rejection, cancer, etc.

The foot scrubber shower brush is a personal care implement that may be placed on a floor and may be adapted to clean a foot without requiring a user to bend down. As a non-limiting example, the floor may be the bottom surface of a shower stall. The foot scrubber shower brush is adapted to clean a right foot by placing a left foot on the left side platform to hold the foot scrubber shower brush in place while the right foot is brushed. The foot scrubber shower brush is adapted to clean the left foot by placing the right foot on the right side platform to hold the foot scrubber shower brush in place while the left foot is brushed.

A device may include a handle component that is configured to permit a user to grasp the handle component during a sanitation process of the user wherein the user sanitizes a distal appendage using the device. The device may include a shaft component that extends in a vertical direction and that is configured to connect the handle component and a connection component. The device may include the connection component that is configured to removably adhere to a surface to permit the device to remain substantially stationary during the sanitation process of the user. The device may include a brush component that is configured to permit the user to perform the sanitation process of the user and that is removably connected to the connection component.

An automatic foot cleaner and callus remover is provided. Through the use of multiple flexible cleaning bands configured to scrub the heel and sole of a user's foot, as well as a toe cleaning mechanism, the automatic foot cleaner and callus remover is capable of cleaning the user's foot and removing any calluses on the user's foot. Optionally, the automatic foot cleaner and callus remover is filled with a liquid such as infused water to assist with the cleaning process.

The shower shuffle is a full-size shower mat with enhanced design to include a foot soaking section and a dead skin removal section. The foot soaking section will be of the shower mat and made up of a sponge/luffa material. The remaining of the Shower Shuffle will be made up of pumice stone for shuffling away dead skin. The bottom will have plastic railings under the sponge section to reinforce safety with weight and level it to the pumice stone. The entire bottom will contain rubber suction cups to keep the full mat in place.

Provided is a beauty tool for nail and skin exfoliation, and specifically, a beauty tool for nail and skin exfoliation including a body, a plate which is coupled to the body and is made of a glass material, a plurality of metal protrusions which are disposed on an upper surface of the plate with a predetermined pattern, and a plurality of concave grooves which are defined with a predetermined depth on the upper surface of the plate and are not covered by the plurality of metal protrusions.

An exfoliating mat has a first side with a perimeter of silicone gel defining an interior area and a second side having an attachment means adjacent each interior corner of the mat. The interior area of the first side further comprises regions of high grit pumice and low grit sandpaper bound within artistic shapes. An electrical vibrating mechanism is secured within the mat subjacent the low grit regions.

An exfoliation device for feet for use in a bathtub or shower comprising washable and replaceable parts created specifically for attending to the feet while standing, without the need to bend over structured and arranged to provide a user with an effortless means of exfoliating the feet and removing dead skin, while standing in the shower or bath.

A foot sanitizing device is provided including at least one foot sanitizing unit having a base and a one foot cavity formed on a top side of the base. A fluid reservoir may be provided on the base and may comprise a reservoir interior in fluid communication with the foot cavity and configured to contain a supply of sanitizing fluid. A user-operable pump may be provided on the fluid reservoir and configured to pump the sanitizing fluid from the fluid reservoir into the at least one foot cavity. At least one foot insert is removably attachable to the foot cavity to provide a contact interface for a user's foot to rest on. The user can place the foot on the foot insert and apply sanitizing fluid onto the foot by operating the pump.

An exfoliation device for feet for use in a bathtub or shower comprising washable and replaceable parts created specifically for attending to the feet while standing, without the need to bend over structured and arranged to provide a user with an effortless means of exfoliating the feet and removing dead skin, while standing in the shower or bath.