The present disclose generally provides pharmaceutical semi-solid hydrogels with entrapped calcium phosphate Comparison of Fitted Curves with Log Time for nanoparticles that demonstrate enhanced Preparations Demonstrating Statistical Significance drug release, retention, and esthetic properties. The hydrogels are particularly useful for topical applications of drug molecules. The present disclosure also relates to methods of administering a pharmaceutical agent by providing a pharmaceutical semi-solid hydrogel containing at least one pharmaceutical agent and administering it to a subject in need thereof.

This invention relates to strontium-phosphate microparticles that incorporate radioisotopes for radiation therapy and imaging.

This invention relates to strontium-phosphate microparticles that incorporate radioisotopes for radiation therapy and imaging.

An object of the present invention is to provide anhydrous dibasic calcium phosphate having good powder flowability and good dispersibility in water. An anhydrous dibasic calcium phosphate powder containing agglomerated particles formed by agglomerating anhydrous dibasic calcium phosphate particles having a modal pore diameter/mean particle diameter ratio of 0.2 to 0.34 exhibits good powder flowability and good dispersibility in water.

An object of the present invention is to provide anhydrous dibasic calcium phosphate having good powder flowability and good dispersibility in water. An anhydrous dibasic calcium phosphate powder containing agglomerated particles formed by agglomerating anhydrous dibasic calcium phosphate particles having a modal pore diameter/mean particle diameter ratio of 0.2 to 0.34 exhibits good powder flowability and good dispersibility in water.

Apatite pretreatment methods are provided. The method is applied to the apatite solid surface prior to first chromatographic use. In one embodiment, the method may be achieved by contacting an apatite solid surface with a phosphate buffered solution at a pH of at least about 6.5 and contacting the apatite solid surface with a solution having a hydroxide.

Apatite pretreatment methods are provided. The method is applied to the apatite solid surface prior to first chromatographic use. In one embodiment, the method may be achieved by contacting an apatite solid surface with a phosphate buffered solution at a pH of at least about 6.5 and contacting the apatite solid surface with a solution having a hydroxide.

An adsorption method adsorbs a substance by using a tube-shaped apatite crystal. The apatite crystal may be a monocrystal given by a general formula M.sup.2.sub.5(PO.sub.4).sub.3X (M.sup.2 denotes at least one element selected from the group consisting of divalent alkali earth metal and Eu, and X denotes at least one element or molecule selected from the group consisting of halogen element and OH). The outer form of the apatite crystal may be a hexagonal prism in which the aperture of a hole formed on a top surface or bottom surface of the hexagonal prism may be hexagonal.

An adsorption method adsorbs a substance by using a tube-shaped apatite crystal. The apatite crystal may be a monocrystal given by a general formula M.sup.2.sub.5(PO.sub.4).sub.3X (M.sup.2 denotes at least one element selected from the group consisting of divalent alkali earth metal and Eu, and X denotes at least one element or molecule selected from the group consisting of halogen element and OH). The outer form of the apatite crystal may be a hexagonal prism in which the aperture of a hole formed on a top surface or bottom surface of the hexagonal prism may be hexagonal.

An aqueous solution containing 30 ppm or more of carbon dioxide is brought into contact with a steel-making slag to elute phosphorus and calcium contained in the steel-making slag into the aqueous solution. Subsequently, carbon dioxide is removed from the aqueous solution to precipitate a mixture comprising a phosphorus compound and a calcium compound. In this manner, a mixture comprising a phosphorus compound and a calcium compound and containing phosphorus in an amount of 1% by mass or more in terms of phosphorus atom content can be produced.