C07C43/202

METHOD FOR PRODUCING 1,1'-BINAPHTHYL DERIVATIVES AND 1,1'-BINAPHTHYL DERIVATIVES
20190062246 · 2019-02-28 ·

In a production method of the present disclosure, a 1,1-binaphthyl precursor derivative, an organic acid, and an iodinating or brominating agent are mixed. The 1,1-binaphthyl precursor derivative has a 1,1-binaphthyl skeleton and has an electron-donating group at the 2-position of the 1,1-binaphthyl skeleton and at the 2-position of the 1,1-binaphthyl skeleton, and the electron-donating group contains an oxygen atom directly bonded to the skeleton. With the production method of the present disclosure, a 1,1-binaphthyl derivative having a substituent introduced at the 8-position and/or 8-position of the 1,1-binaphthyl skeleton can be obtained. The 1,1-binaphthyl derivative obtained by the production method of the present disclosure can be a compound further having a substituent introduced at at least one position selected from the 4-position, 4-position, 5-position, 5-position, 6-position, and 6-position of the 1,1-binaphthyl skeleton.

Ion channel antagonists/blockers and uses thereof

Provided are ion channel antagonists/blockers and uses thereof. Specifically, it provides the compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates or prodrugs, preparation method therefor and application thereof. Definition of each group in the formula can be found in the specification for details. Provided is also pharmaceutical composition useful for treatment of heart disease and other ion channel related diseases. ##STR00001##

Low viscosity low volatility lubricating oil base stocks and processes for preparing same

A composition that includes one or more compounds represented by the formula
R.sub.1OR.sub.2
wherein R.sub.1 is a substituted or unsubstituted aryl or polyaryl group having from about 4 to about 40 carbon atoms, and R.sub.2 is a substituted or unsubstituted, linear or branched, alkyl group having from about 4 to about 40 carbon atoms. The composition has a viscosity (Kv.sub.100) from about 1 to about 10 cSt at 100 C. as determined by ASTM D-445, a viscosity index (VI) from about 100 to about 300 as determined by ASTM D-2270, and a Noack volatility of no greater than 50 percent as determined by ASTM D-5800. The disclosure also relates to a process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method of reducing boundary friction and improving dispersancy of polar additives of a lubricating oil by using as the lubricating oil a formulated oil containing the composition.

LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME

A composition that includes one or more compounds represented by the formula


R.sub.1OR.sub.2

wherein R.sub.1 is a substituted or unsubstituted aryl or polyaryl group having from about 4 to about 40 carbon atoms, and R.sub.2 is a substituted or unsubstituted, linear or branched, alkyl group having from about 4 to about 40 carbon atoms. The composition has a viscosity (Kv.sub.100) from about 1 to about 10 cSt at 100 C. as determined by ASTM D-445, a viscosity index (VI) from about 100 to about 300 as determined by ASTM D-2270, and a Noack volatility of no greater than 50 percent as determined by ASTM D-5800. The disclosure also relates to a process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method of reducing boundary friction and improving dispersancy of polar additives of a lubricating oil by using as the lubricating oil a formulated oil containing the composition.

THERMOPLASTIC RESIN, METHOD FOR MANUFACTURING SAME, AND OPTICAL LENS

Provided is a thermoplastic resin including constituent units represented by general formula (1). (In formula (1), R.sub.1 and R.sub.2 each independently represents: a hydrogen atom; a fluorine atom; a chlorine atom; a bromine atom; an iodine atom; a C1-6 alkyl group; a monocyclic or polycyclic C6-36 aryl group; a monocyclic or polycyclic heteroaryl group having 5-36 ring atoms, 1, 2, 3, or 4 of the ring atoms being selected from nitrogen, sulfur, and oxygen, and the other ring atoms being carbon in the heteroaryl group; a C2-6 alkenyl group; a C1-6 alkoxy group; or a C7-17 aralkyl group. In formula (1), X, a, and b are each as described in the present specification.)

##STR00001##

Thermoplastic resin, method for manufacturing same, and optical lens

Provided is a thermoplastic resin including constituent units represented by general formula (1). (In formula (1), R1 and R2 each independently represent: a hydrogen atom; a fluorine atom; a chlorine atom; a bromine atom; an iodine atom; a C1-6 alkyl group; a monocyclic or polycyclic C6-36 aryl group; a monocyclic or polycyclic heteroaryl group having 5-36 ring atoms, 1, 2, 3, or 4 of the ring atoms being selected from nitrogen, sulfur, and oxygen, and the other ring atoms being carbon in the heteroaryl group; a C2-6 alkenyl group; a C1-6 alkoxy group; or a C7-17 aralkyl group. In formula (1), X, a, and bare each as described in the present specification.) ##STR00001##

Method of manufacturing crystalline and amorphous forms of 6,6′-diphenyl-2,2′-bis(2-hydroxyethoxy)-1,1′-binaphthyl and thermoplastic resin therefrom

Methods for forming a crystalline form or an amorphous form of 6,6-diphenyl-2,2-bis(2-hydroxyethoxy)-1,1-binaphthyl and thermoplastic resin therefrom. According to one embodiment, a crystal solvate form of 6,6-diphenyl-2,2-bis(2-hydroxyethoxy)-1,1-binaphthyl, which contains in its crystals from 0.3 to 1.2 mol of an organic solvent per 1 mol of 6,6-diphenyl-2,2-bis(2-hydroxyethoxy)-1,1-binaphthyl, where the organic solvent is selected from the group consisting of methanol, toluene, and methyl ethyl ketone.

Light emitting element

A light emitting element includes a first electrode, a second electrode disposed on the first electrode, and an emission part disposed between the first electrode and the second electrode and including a first emission layer and a second emission layer disposed on the first emission layer, the first emission layer may include a first host, and a first dopant, and the second emission layer may include a hole transport host different from the first host, an electron transport host, and a second dopant. A first hole mobility of the first host may be in a range of about 5.010.sup.6 cm.sup.2/Vs to about 1.010.sup.3 cm.sup.2/Vs, a second hole mobility of a host mixture including the hole transport host and the electron transport host may be in a range of about 1.010.sup.6 cm.sup.2/Vs to about 1.010.sup.4 cm.sup.2/Vs, and the first hole mobility may be larger than the second hole mobility.