The present disclosure relates to HIF-2 inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2 scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

Provided are a condensed cyclic compound, a composition including the same, and an organic light-emitting device including a thin film formed from the composition. The condensed cyclic compound is represented by following Formula, has a molecular weight of about 400 to about 10,000, and comprises at least one cross-linkable group:

##STR00001##

Provided are a condensed cyclic compound, a composition including the same, and an organic light-emitting device including a thin film formed from the composition. The condensed cyclic compound is represented by following Formula, has a molecular weight of about 400 to about 10,000, and comprises at least one cross-linkable group:

##STR00001##

The present disclosure relates to HIF-2 inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2 scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

The present disclosure relates to HIF-2 inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2 scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

The present invention relates to compounds according to formula (I) and to heat-curable resin compositions based on polymaleimide resin systems comprising such compounds as co-monomers: wherein R.sup.1 signifies an 1-alkenyl- or 2-alkenyl group with 3 to 6 carbon atoms, wherein R.sup.2 signifies hydrogen or an alkoxy group with up to 2 carbon atoms, wherein R.sup.3 signifies hydrogen or an alkyl group with up to 4 carbon atoms, and wherein R.sup.4 signifies hydrogen or an alkyl group with up to 4 carbon atoms. The present invention also relates to crosslinked resins obtainable by curing such compositions. Compounds of the present invention can be used amongst others in fields like structural adhesives, matrix resins for fiber prepregs, moulding compounds, as well as structural and/or electrical composites.

##STR00001##

The present invention relates to compounds according to formula (I) and to heat-curable resin compositions based on polymaleimide resin systems comprising such compounds as co-monomers: wherein R.sup.1 signifies an 1-alkenyl- or 2-alkenyl group with 3 to 6 carbon atoms, wherein R.sup.2 signifies hydrogen or an alkoxy group with up to 2 carbon atoms, wherein R.sup.3 signifies hydrogen or an alkyl group with up to 4 carbon atoms, and wherein R.sup.4 signifies hydrogen or an alkyl group with up to 4 carbon atoms. The present invention also relates to crosslinked resins obtainable by curing such compositions. Compounds of the present invention can be used amongst others in fields like structural adhesives, matrix resins for fiber prepregs, moulding compounds, as well as structural and/or electrical composites.

##STR00001##

The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.

This disclosure provides low viscosity, low volatility aryl ether compounds represented by formula (1): ##STR00001##
and represented by formula (2): ##STR00002##
wherein R.sub.1 is the same or different and is a linear or branched alkyl group having from 1 to 20 carbon atoms; R.sub.2 is the same or different and is hydrogen or an alkyl group having from 1 to 4 carbon atoms; and n is the same or different and is a value from 0 to 8. This disclosure also provides processes for producing the aryl ether compounds, lubricating oil basestocks and lubricating oils containing one or more of the aryl ether compounds, and a method for improving one or more of solubility and dispersancy of polar additives and/or sludge in a lubricating oil by using as the lubricating oil a formulated oil containing one or more of the aryl ether compounds.